In vitro screening of extracts from 38 marine animal resources for novel cosmeceutical activities
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Marine resources have various biological activities and their constituents are more novel than those of land organisms. Several biologically active constituents have been found in marine organisms. Recently, many studies have reported that marine animals (MAs) can be used as functional ingredients in functional foods or nutraceutical due to their health benefits. However, no studies have extensively investigated the cosmeceutical activities of MAs extracts. Here, 70% ethanol extracts of 38 MAs were investigated for their activities of whitening and anti-aging properties for use as materials in novel cosmeceuticals. Anti-aging activities were determined by skin aging-related enzyme activities (anti-collagenase, anti-elastase, anti-hyaluronidase) and whitening activities (anti-tyrosinase, anti-3,4-dihydroxyl-L-phenylalanine [DOPA] oxidation) evaluated by colorimetric method. Among the 38 MAs, we found that Urechis unicinctus and Petrosia corticata extracts showed the strongest inhibitory effects against tyrosinase and DOPA oxidation, respectively. Our results additionally showed that Protankyra bidentata extract might provide a major source of anti-hyaluronidase and anti-elastase; meanwhile, anti-collagenase effects were similar in most MAs. Overall, these results suggest that extracts of marine animals have potential as a tyrosinase, collagenase, elastase, and hyaluronidase inhibitors. Taken together, MA resources could be considered as a novel cosmeceutical agent to be applied in cosmetic industry.
Abstract
Marine resources have various biological activities and their constituents are more novel than those of land organisms. Several biologically active constituents have been found in marine organisms. Recently, many studies have reported that marine animals (MAs) can be used as functional ingredients in functional foods or nutraceutical due to their health benefits. However, no studies have extensively investigated the cosmeceutical activities of MAs extracts. Here, 70% ethanol extracts of 38 MAs were investigated for their activities of whitening and anti-aging properties for use as materials in novel cosmeceuticals. Anti-aging activities were determined by skin aging-related enzyme activities (anti-collagenase, anti-elastase, anti-hyaluronidase) and whitening activities (anti-tyrosinase, anti-3,4-dihydroxyl-L-phenylalanine [DOPA] oxidation) evaluated by colorimetric method. Among the 38 MAs, we found that Urechis unicinctus and Petrosia corticata extracts showed the strongest inhibitory effects against tyrosinase and DOPA oxidation, respectively. Our results additionally showed that Protankyra bidentata extract might provide a major source of anti-hyaluronidase and anti-elastase; meanwhile, anti-collagenase effects were similar in most MAs. Overall, these results suggest that extracts of marine animals have potential as a tyrosinase, collagenase, elastase, and hyaluronidase inhibitors. Taken together, MA resources could be considered as a novel cosmeceutical agent to be applied in cosmetic industry.
참고문헌 (30)
- Bi Q, "Antithrombotic effects of a newly purified fibrinolytic protease from Urechis unicinctus", Thromb Res, 132, pp.E135~44 (2013)
- Bravo K, "Fruits of selected wild and cultivated Andean plants as sources of potential compounds with antioxidant and anti-aging activity", Ind Crops Prod, 85, pp.341~352 (2016)
- Bukhari SNA, "Hyaluronic acid, a promising skin rejuvenating biomedicine : a review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects", Int J Biol Macromol, 120, pp.1682~1695 (2018)
- Chan YY, "Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells", J Ethnopharmacol, 137, pp.1183~1188 (2011)
- Ding Y, "Hyaluronidase inhibitory and antioxidant activities of enzymatic hydrolysate from Jeju island red sea cucumber(Stichopus japonicus)for novel anti-aging cosmeceuticals", J Mar Biosci Biotechnol, 10, pp.62~72 (2018)
- Ebada SS, "Methods for isolation, purification and structural elucidation of bioactive secondary metabolites from marine invertebrates", Nat Protoc, 3, pp.1820~1831 (2008)
- Ferreres F, "Phlorotannin extracts from fucales characterized by HPLC-DAD-ESI-MSn : approaches to hyaluronidase inhibitory capacity and antioxidant properties", Mar Drugs, 10, pp.2766~2781 (2012)
- Gam DH, "Skin-whitening and anti-wrinkle effects of bioactive compounds isolated from peanut shell using ultrasound-assisted extraction", Molecules, 26, pp.1231~ (2021)
- Gupta P, "Screening of antiangiogenic potential of twenty two marine invertebrate extracts of phylum Mollusca from South East coast of India", Asian Pac J Trop Biomed, 1, pp.S129~38 (2014)
- Kyung Hoan Im, "Antioxidant, Anti-Melanogenic and Anti-Wrinkle Effects of Phellinus vaninii", Mycobiology, 47(4), pp.494~505 (2019), 한국균학회[DOI]
- Chanipa Jiratchayamaethasakul, "In vitro screening of elastase, collagenase, hyaluronidase, and tyrosinase inhibitory and antioxidant activities of 22 halophyte plant extracts for novel cosmeceuticals", Fisheries and Aquatic Sciences, 23(1), pp.1~9 (2020), 한국수산과학회[DOI]
- 김인덕, "한방원료의 초임계 추출을 이용한 항노화 및 주름개선 효과", KSBB Journal, 23(6), pp.529~534 (2008), 한국생물공학회
- Kim SK, "Marine cosmeceuticals", J Cosmet Dermatol, 13, pp.56~67 (2014)
- 김세권, "Prospective of the Cosmeceuticals Derived from Marine Organisms", Biotechnology and Bioprocess Engineering, 13(5), pp.511~523 (2008), 한국생물공학회
- Li X, "The efficient enrichment of marine peptides from the protein hydrolysate of the marine worm Urechis unicinctus by using mesoporous materials MCM-41, SBA-15 and CMK-3", Anal Methods, 13, pp.2405~2414 (2021)
- Lin RD, "New whitening constituents from Taiwan-native Pyracantha koidzumii : structures and tyrosinase inhibitory analysis in human epidermal melanocytes", Int J Mol Sci, 16, pp.28598~28613 (2015)
- Martins A, "Marketed marine natural products in the pharmaceutical and cosmeceutical industries : tips for success", Mar Drugs, 12, pp.1066~1101 (2014)
- Momtaz S, "Inhibitory activities of mushroom tyrosine and DOPA oxidation by plant extracts", S Afr J Bot, 74, pp.577~582 (2008)
- Mukherjee PK, "Bioactive compounds from natural resources against skin aging", Phytomedicine, 19, pp.64~73 (2011)
- Ndlovu G, "In vitro determination of the anti-aging potential of four southern African medicinal plants", BMC Complement Altern Med, 13, pp.304~ (2013)
- Oh HY, "Isolation of an invertebrate-type lysozyme from the nephridia of the echiura, Urechis unicinctus, and its recombinant production and activities", Fish Shellfish Immunol, 79, pp.351~362 (2018)
- 박원민, "Anti-Melanogenesis and Anti-Wrinkle Effects of Sargassum micracanthum Extracts", 한국미생물·생명공학회지, 44(1), pp.19~25 (2016), 한국미생물·생명공학회[DOI]
- Peres PS, "Photoaging and chronological aging profile : understanding oxidation of the skin", J Photochem Photobiol B, 103, pp.93~97 (2011)
- Shen X, "Purification and antitumor effect evaluation of Protankyra bidentata antitumor factor", Chin J Marine Drugs, 32, pp.1~6 (2013)
- Shirzad M, "Anti-elastase and anti-collagenase potential of Lactobacilli exopolysaccharides on human fibroblast", Artif Cells Nanomed Biotechnol, 46(Suppl 1), pp.1051~1061 (2018)
- Sung WS, "Antimicrobial effect and membrane-active mechanism of Urechistachykinins, neuropeptides derived from Urechis unicinctus", FEBS Lett, 582, pp.2463~2466 (2008)
- Thring TSA, "Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants", BMC Complement Altern Med, 9, pp.27~ (2009)
- Tischler D, "A perspective on enzyme inhibitors from marine organisms", Mar Drugs, 18, pp.431~ (2020)
- Wahab NA, "Assessment of antioxidant capacity, anti-collagenase and anti-elastase assays of Malaysian unfermented cocoa bean for cosmetic application", Nat Prod Chem Res, 2, pp.132~ (2014)
- Wang L, "Protective effect of green tea catechin against urban fine dust particle-induced skin aging by regulation of NF-κB, AP-1, and MAPKs signaling pathways", Environ Pollut, 252, pp.1318~1324 (2019)