본문 바로가기
KERD
논문KCI 등재

Photobacterium damselae의 디스크 확산법 결과에 대한 Epidemiological Cut-off Value의 결정

Epidemiological Cut-off Values Generated for Disc Diffusion Data from Photobacterium damselae

0

조회

0

다운로드

3

인용

0

참고문헌

키워드

주제분류수산학

초록

In this study, epidemiological cut-off values were estimated for 44 Photobacterium damselae isolates, since clinical breakpoints have not been established for this pathogenic bacterium. The susceptibility of the isolates to 10 antibiotics was evaluated using internationally standardized disc diffusion protocols. Normalized resistance interpretation was used to generate statistically valid epidemiological cut-off values for the susceptibility data. There were not enough strains exhibiting full sensitivity to ampicillin and amoxicillin to allow analysis of these antibiotics. Because there were only a marginally sufficient number of strains exhibiting full sensitivity to oxytetracycline, the cut-off value generated provided only a provisional estimate. The valid wild-type cut-off values were <13, 13, 9, 22, 25, 27, and 28 mm for gentamicin, cephalexin, erythromycin, oxolinic acid, flumequine, florfenicol, and sulfamethoxazole/ trimethoprim, respectively. The application of these cut-off values should greatly facilitate the rational selection of antibiotics for use in commercial fish farms.

Abstract

In this study, epidemiological cut-off values were estimated for 44 Photobacterium damselae isolates, since clinical breakpoints have not been established for this pathogenic bacterium. The susceptibility of the isolates to 10 antibiotics was evaluated using internationally standardized disc diffusion protocols. Normalized resistance interpretation was used to generate statistically valid epidemiological cut-off values for the susceptibility data. There were not enough strains exhibiting full sensitivity to ampicillin and amoxicillin to allow analysis of these antibiotics. Because there were only a marginally sufficient number of strains exhibiting full sensitivity to oxytetracycline, the cut-off value generated provided only a provisional estimate. The valid wild-type cut-off values were <13, 13, 9, 22, 25, 27, and 28 mm for gentamicin, cephalexin, erythromycin, oxolinic acid, flumequine, florfenicol, and sulfamethoxazole/ trimethoprim, respectively. The application of these cut-off values should greatly facilitate the rational selection of antibiotics for use in commercial fish farms.

참고문헌 (23)

  1. Ruben Avendaño-Herrera, "Estimation of epidemiological cut-off values for disk diffusion susceptibility test data for Streptococcus phocae", Aquaculture, 314(1-4), pp.44~48 (2011), Elsevier BV[DOI]
  2. 조영아, "우리나라 양식 강도다리, Platichthys stellatus에서 분리된 Photobacterium damselae subsp. piscicida의 특성", 한국어병학회지, 26(2), pp.77~88 (2013), 한국어병학회[DOI]
  3. T.-H. Chiu, "Antibiotic resistance and molecular typing of Photobacterium damselae subsp. damselae, isolated from seafood", Journal of Applied Microbiology, 114(4), pp.1184~1192 (2013), Wiley-Blackwell[DOI]
  4. Methods for Antimicrobial Disk Susceptibility Testing of Bacteria Isolated From Aquatic Animals; Approved Guideline, "CLSI.", Clinical and Laboratory Standards Institute, ~, pp.CLSI document M42-A (2006)
  5. Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement, "CLSI.", Clinical and Laboratory Standards Institute, ~, pp.CLSI document M100-S20 (2010)
  6. Generation, presentation and application of antimicrobial susceptibility test data for bacteria of animal origin: a report, "CLSI.", Clinical and Laboratory Standards Institute, ~, pp.Clinical and laboratory standards institute document VET05-R (2011)
  7. Performance standards for antimicrobial susceptibility testing of bacteria isolated from aquatic animals; Second informational supplement, "CLSI.", Clinical and Laboratory Standards Institute, ~, pp.CLSI document VET03 (2014), VET04-S2
  8. "Definition of clinical breakpoints and epidemiological cut off values" (2016)[URL]
  9. "EUCAST Disk Diffusion Test Reading guide, Version 4.0" (2016)[URL]
  10. M. Kawanishi, "Drug resistance and random amplified polymorphic DNA analysis of Photobacterium damselae ssp. piscicida isolates from cultured Seriola (yellowtail, amberjack and kingfish) in Japan", Letters in Applied Microbiology, 42(0), pp.648~653 (2006), Wiley-Blackwell[DOI]
  11. Göran Kronvall, "Determination of the real standard distribution of susceptible strains in zone histograms", International Journal of Antimicrobial Agents, 22(1), pp.7~13 (2003), Elsevier BV[DOI]
  12. 권문경, "넙치, Paralichthys olivaceus에서 병원성 Photobacterium damselae subsp. damselae의 분리", 한국어병학회지, 18(3), pp.205~214 (2005), 한국어병학회
  13. Labella A, "Recent Advances in Fish Farms", pp.135~152 (2011), InTech
  14. Yun-Jin Lim, "Epidemiological cut-off values for disc diffusion data generated by standard test protocols from Edwardsiella tarda and Vibrio harveyi", Aquaculture International, 24(4), pp.1153~1161 (2016), Springer Nature[DOI]
  15. Ron A. Miller, "Epidemiological cut-off values for antimicrobial agents against Aeromonas salmonicida isolates determined by frequency distributions of minimal inhibitory concentration and diameter of zone of inhibition data", American Journal of Veterinary Research, 67(11), pp.1837~1843 (2006), American Veterinary Medical Association (AVMA)[DOI]
  16. Lisa Nonaka, "Novel Conjugative Transferable Multiple Drug Resistance Plasmid pAQU1 from Photobacterium damselae subsp. damselae Isolated from Marine Aquaculture Environment", Microbes and Environments, 27(3), pp.263~272 (2012), Japanese Society of Microbial Ecology[DOI]
  17. Neil M. Ruane, "Application of normalised resistance interpretation to disc diffusion data on the susceptibility of Aeromonas salmonicida to three quinolone agents", Aquaculture, 272(1-4), pp.156~167 (2007), Elsevier BV[DOI]
  18. Pete Smith, "Impact of inter-lab variation on the estimation of epidemiological cut-off values for disc diffusion susceptibility test data for Aeromonas salmonicida", Aquaculture, 272(1-4), pp.168~179 (2007), Elsevier BV[DOI]
  19. Smith P, "Antimicrobial resistance in aquaculture, Changing trends in managing aquatic animal disease emergencies", Review Scientifique et Technique Office International des Epizooties, 27, pp.243~264 (2008)
  20. Smith P., "Improving biosecurity through prudent and responsible use of veterinary medicines in aquatic food production", pp.99~118 (2012), FAO Fisheries and Aquaculture Technical Paper
  21. P Smith, "Effect of incubation temperature and time on the precision of data generated by antibiotic disc diffusion assays", Journal of Fish Diseases, 38(7), pp.629~636 (2015), Wiley-Blackwell[DOI]
  22. A. Thyssen, "In vitro antimicrobial susceptibility of Photobacterium damselae subsp. piscicida to 15 different antimicrobial agents", Aquaculture, 200(3-4), pp.259~269 (2001), Elsevier BV[DOI]
  23. Norio YASUNAGA, "Therapeutic effect of florfenicol on experimentally induced pseudotuberculosis in yellowtail.", Fish Pathology, 23(1), pp.1~5 (1988), The Japanese Society of Fish Pathology[DOI]

관련 논문AI추천

Streptococcus parauberis의 디스크 확산법 결과에 대한 Epidemiological Cut-off Value의 설정권문경, 김남은, 김도형, 김아란, 김윤재, 노형진, 서정수, 이윤항, 이지훈, 천원경한국수산과학회 · 한국수산과학회지2019 · 제52권 제4호아미노글리코사이드 계열 항생제의 Edwardsiella piscicida에 대한 내성 검출 기준 설정 및 유효성 평가권문경, 김도형, 김민교, 김주성, 박지연, 서정수, 신초윤, 이지훈, 정지민, Cahyani Fortunitawanli수산생명의학회 · 한국어병학회지2025 · 제38권 제1호Determination of epidemiological tetracycline MIC cut-off value for Vibrio ichthyoenteri김도형, 김진우, 원경미, 이덕찬, 이순정, 조미영, 지보영, 한현자수산생명의학회 · 한국어병학회지2011 · 제24권 제2호양식 넙치 (Paralichthys olivaceus)에서 분리된 Edwardsiella tarda에 대한 항균제 MIC 값 분포김명석, 박명애, 서정수, 정승희, 조지영, 최혜승수산생명의학회 · 한국어병학회지2012 · 제25권 제3호어류 병원성 세균의 MIC 결정을 위한 MIC Panel의 최적화 배양 조건 확립강미래, 김명석, 김예지, 우수지, 이다원, 전려진, 정준범한국수산과학회 · 한국수산과학회지2020 · 제53권 제3호양식 넙치에서 분리한 어병세균의 lincomycin에 대한 내성 유전자의 분포고예진, 김성현, 김예지, 이영준, 전려진, 정준범, 한소리수산생명의학회 · 한국어병학회지2022 · 제35권 제1호

이 간행물의 다른 논문 (22건)