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2004년 진주지역 Streptococcus pyogenes의 T 항원과 emm 유전자형 분포

Distribution of T types and emm Genotypes of Streptococcus pyogenes in Jinju, 2004

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참고문헌

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초록

배경 : Streptococcus pyogenes의 역학조사를 위해 T 항원형과emm 유전자형이 이용된다. 진주에서 10년 동안 3회에 걸쳐 대규모로 인두배양을 시행하여 S. pyogenes의 역학적 특성을 살펴보았다. 방법 : 2004년 경남 진주지역 초등학생에서 분리된 S. pyogenes328균주를 대상으로 슬라이드 응집법으로 T항원형 검사를 시행하였고, 유전자 증폭 및 염기서열 분석법으로 emm 유전자형을 조사하였다. 동정된 T 항원형과 emm 유전자형 분포를 이전 결과와비교하였다.결과 : S. pyogenes 328균주의 T 항원형 분포를 살펴보면 T5/27/44가 29.6%로 가장 흔하였고 T12와 T6이 각각 13.4%와 10.7%이었다. 동정되지 않는 T nontypeable이 3.4%이었다. emm 유전자형 조사에서는 emm44/61이 29.3%로 가장 흔하였고 emm6과 emm1이 각 11.6%와 9.8%로 그 다음을 차지하였다.

참고문헌 (21)

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