본문 바로가기
KERD
논문KCI 등재

Organ-specific antigens of Clonorchis sinensis

홍성태|최민호|정병석|Shunyu Li
대한기생충학ㆍ열대의학회 (The Korean Society For Parasitology and Tropical Medicine)|2004.12|Parasites, Hosts and Diseases|제42권 제4호|pp. 169-174

2

조회

0

다운로드

1

인용

0

참고문헌

주제분류예방의학/직업환경의학

초록

Abstract

This study intended to find out specific proteins from different organs of Clonorchis sinensis. Crude extract, organ-specific antigens and excretory-secretory (ES) antigen were analyzed by immunoblot with infected human sera. The bands of 7- and 17-kDa were main component of intestinal fluid and ES protein but commonly found in all organ-specific antigens. The protein of 17 kDa was observed from ES antigen, intestinal fluid, eggs and sperms, 26- and 28-kDa bands were from the uterus, vitellaria, and ovary, and 34-, 37-, 43- and 50-kDa bands were mainly from the testis and sperms. Serum of mice immunized with sperms reacted to the 50-kDa band by immunoblotting. Immunohistochemical staining with the immune serum showed a positive reaction exclusively at the seminal receptacle. The present results showed that the 7-kDa protein is a common antigen of every part or organ of C. sinensis, but different organs express their specific antigenic protein bands.

참고문헌 (18)

  1. "Excretory-secretory antigen is better than crude antigen forthe serodiagnosis of clonorchiasis by ELISA", 41, pp.35~39 (2003)
  2. "Specific and common antigens of Clonorchis sinensis and Opisthorchis viverrini (Opisthorchidae, Trematoda)", 41, pp.155~163 (2003)
  3. "Characterization of partially purified 8 kDa antigenic protein of Clonorchis sinensis", 40, pp.83~88 (2002)
  4. "Molecular cloning and immunolocalization of the 17 kDa myoglobin of Clonorchis sinensis", pp.365~368 (2003)
  5. "Antigenic profile and localization of Clonorchis sinensis proteins in the course of infection", 39, pp.307~312 (2001)
  6. "Molecular cloning and immunological characterization of phosphoglycerate kinase from Clonorchis sinensis", 108, pp.207~216 (2000)
  7. "Clonorchis sinensis. International Handbook of Foodborne Pathogens", pp.581~592 (2003), Marcel & Dekker
  8. "Immunoblot patterns of clonorchiasis", 35, pp.87~93 (1997)
  9. "Clonorchis sinensis: Molecular cloning and characterization of 28-kDa glutathione S-transferase", 97, pp.186~195 (2001)
  10. "Immune reactions between excretory-secretory antigens and specific antibodies of Clonorchis sinensis before and after praziquantel treatment in experimentally infected rabbits. Korean J Parasitol 32", pp.35~42 (1994)
  11. "A Clonorchis sinensis-specific antigen that detects active human clonorchiasis", 36, pp.37~45 (1998)
  12. "Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227", pp.680~685 (1970)
  13. "The identification of a Clonorchis sinensis gene encoding an antigenic egg protein" (2004), Parasitol Res (in press).
  14. "Prevalence of intestinal parasitic infection in Korea", pp.20~48 (1997), Ministry of Health and Welfare and Korea Association of Health
  15. "The current pathobiology and chemotherapy of clonorchiasis", 24, pp.5~141 (1986)
  16. "Cloning and characterization of Clonorchis sinensis myoglobin using immune sera against excretory-secretory antigens", 91, pp.338~343 (2003)
  17. "localization and partial characterization of tubulin. Parasitol Res 78", pp.103~107 (1992)
  18. "Analysis of Clonorchis sinensis antigens and diagnosis of clonorchiasis using monoclonal antibodies. Korean J Parasitol 29", pp.293~310 (1991)

관련 논문AI추천

Specific and common antigens of Clonorchis sinensis and Opisthorchis viverrini (Opisthorchidae, Trematoda)류진숙, 이미정, 이순옥, 채종일, 최민호, 홍성태, Byung-SukCHUNG, PaiboonSITHITHAWORN, SmarnTESANA대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2003 · 제41권 제3호Development of resistance to reinfection by Clonorchis sinensis in rats이매정, 전동규, 정병석, 최민호, 홍성태, Hongman Zhang, Shunyu Li대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2004 · 제42권 제1호Characterization of partially purified 8 kDa antigenic protein of Clonorchis sinensis이미정, 정영배, 홍성태, Byung-SukCHUNG, Hyun-JongYANG, Min-hoCHOI, Shun-YuLEE대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2002 · 제40권 제2호Excretory-secretory antigen is better than crude antigen for the serodiagnosis of clonorchiasis by ELISA이순옥, 최민호, 홍성태대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2003 · 제41권 제1호Susceptibility of experimental animals to reinfection with Clonorchis sinensis손운목, 최민호, 홍성태, Hongman Zhang대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2006 · 제44권 제2호Metacercarial proteins interacting with WD40-repeat protein of Clonorchis sinensis김태임, 정용제, 조표연, 최민호, 홍성종, 홍성태, Shunyu Li대한기생충학ㆍ열대의학회 · Parasites, Hosts and Diseases2007 · 제45권 제3호

이 간행물의 다른 논문 (7건)

Developmental surface ultrastructure of Macroorchis spinulosus in albino rats우호춘, 홍성종, 권오실pp. 151-157Codon usage and bias in mitochondrial genomes of parasitic platyhelminthesDavid Blair, Le Thanh Hoa, Donald Peter McManuspp. 159-167Effects of iNOS inhibitor on IFN-gamma production and apoptosis of splenocytes in genetically different strains of mice infected with Toxoplasma gondii이계성, 이영하, 최인욱, 신대환, 강기만, 이재호pp. 175-183Influence of calcium ion on host cell invasion and intracellular replication by Toxoplasma gondii이영하, 민득영, 송현욱, 안명희, 류재숙, 주경환pp. 185-193Immunization effect of recombinant P27/30 protein expressed in Escherichia coli against the hard tick Haemaphysalis longicornis (Acari: Ixodidae) in rabbits유명조pp. 195-200
원문 보기