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Susceptibility of experimental animals to reinfection with Clonorchis sinensis

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Abstract

The present study observed the resistance to reinfection with Clonorchis sinensis in various experimentaltion in rats, mice, hamsters, guinea pigs, rabbits, and dogs were 79.7%, 58.0%, -12.6%, 54.8%, 62.6%, and 6.0%,respectively. Worms recovered from reinfected rats and mice were immature, and significantly smaller than thosefrom the primarily infected (P < 0.01), whereas those from other animals were fully matured to adults. These findingsindicate that the protective response against reinfection with is prominent in rats and mice, and that theymay be a good animal model to investigate the mechanism of resistance to reinfection with C. sinensis.

참고문헌 (9)

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  2. "Cytokine responses in mice infectedwith Clonorchis sinensis", 91, pp.87~93 (2003)
  3. "Development of resistance to reinfection byClonorchis sinensisin rats", 42, pp.19~26 (2004)
  4. "The immune response and the evaluation of acquired immunity against gastroin-testinal nematodes in cattle: a review", 120, pp.25~42 (2000)
  5. "Resistance of the ratto reinfection with Fasciola hepaticaand the possibleinvolvement of intestinal eosinophil leucocytes", pp.41~44 (1978)
  6. "Acquired resistance to Opisthorchis viverriniin the hamster", pp.800~802 (1982)
  7. "partial success in adoptively transferringimmunity with spleen cells and serum in the hamster"
  8. "Resistance to reinfection with Schistosoma japon-icum in the mouse", pp.133~139 (1983)
  9. "Eggpositive rates of Clonorchis sinensisand intestinalhelminths among residents in Kagye-ri" (1994)

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