생체모방형 무릎 관절모델의 압축력 측정
Measurement of the compressive Force on the Biomimetic Knee Joint Model
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Articular cartilage in the human body plays an important role in protecting the bones from a variety of physical stress when the body is walking or moving. A specific mechanical stimulation may be a key factor of cartilage tissue regeneration in vitro in tissue engineering. While the biomechanics of the human knee has been studied extensively, less is known about the experimental measurement of knee joint. Therefore, a custom-made bioreactor was developed to apply CPM mechanism. As a results, the compressive force on a femur is different value about not only each Zone of biomimetic knee joint model and also lateral and medial part. This study is an initial biomechanical assessment of the differences in human knee joint and biomimetic knee joint model to know the optimal condition of regeneration cartilage tissue in bioreactor.
Abstract
Articular cartilage in the human body plays an important role in protecting the bones from a variety of physical stress when the body is walking or moving. A specific mechanical stimulation may be a key factor of cartilage tissue regeneration in vitro in tissue engineering. While the biomechanics of the human knee has been studied extensively, less is known about the experimental measurement of knee joint. Therefore, a custom-made bioreactor was developed to apply CPM mechanism. As a results, the compressive force on a femur is different value about not only each Zone of biomimetic knee joint model and also lateral and medial part. This study is an initial biomechanical assessment of the differences in human knee joint and biomimetic knee joint model to know the optimal condition of regeneration cartilage tissue in bioreactor.
참고문헌 (13)
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