특발성 망막전막에서 유리체절제술 전후 미세시야계를 이용한 구조와 기능의 상관관계 분석
Morphologic and Functional Evaluation before and after Vitrectomy in Idiopathic Epiretinal Membrane Patients Using Microperimetry
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
목적: 특발성 망막전막으로 유리체절제술과 막제거술을 시행한 환자에서 빛간섭단층촬영과 미세시야계 검사를 사용하여 시세포 접합부 구조와 망막민감도의 관계를 알아보고자 한다. 대상과 방법: 특발성 망막전막에 대한 수술을 받은 환자 20명 20안을 대상으로 술 전과 술 후 빛간섭단층촬영과 미세시야계 검사를시행하였다. 시세포 접합부의 구조, 시력, 망막민감도, 주시안정도를 측정하였으며 각 인자간에 유의한 관련이 있는지 알아보았다. 결과: 수술 후 망막민감도는 유의하게 증가하였으며(p˂0.001), 시세포 접합부 결손범위는 변화가 없었다. 술 전 시세포 접합부 결손범위는 술 전, 후 망막민감도와 유의한 상관관계를 보였으나(p=0.035, p=0.006), 주시안정도와는 유의한 상관관계를 보이지 않았다. 결론: 망막민감도는 시세포 접합부 결손 범위와 유의한 상관관계를 보였으며, 구조변화에 따른 망막의 기능을 객관적으로 정량화할수 있을 것으로 생각한다.
Abstract
Purpose: To investigate the relationship between photoreceptor inner/outer segment (IS/OS) integrity and macular sensitivity after epiretinal membrane (ERM) surgery using spectral-domain optical coherence tomography combined with microperimetry. Methods: 20 eyes of 20 patients with idiopathic ERM who underwent pars plana vitrectomy for ERM removal were prospectively reviewed. The IS/OS defect diameter, BCVA, macular sensitivity, and fixation stability were measured using spectral-domain optical coherence tomography combined with microperimetry. The correlation of these factors was analyzed. Results: The macular sensitivity improved after successful ERM surgery (p < 0.001), but the IS/OS defect diameter has not improved. The preoperative and postoperative macular sensitivity were negatively correlated with preoperative IS/OS defect diameter (p = 0.035, p = 0.006). The fixation stability was not correlated with preoperative IS/OS defect diameter. Conclusions: Macular sensitivity showed significant correlation with IS/OS defect diameter. Macular sensitivity is vital functional parameter allows subjective quantification of the retinal function and reflects morphologic changes.
참고문헌 (38)
- McDonald HR, "Surgical management of idiopathic epiretinal membranes", Ophthalmology, 93, pp.978~983 (1986)
- Choi YK, "Result of surgery for epiretinal membrane and their recurrence", J Korean Ophthalmol Soc, 41, pp.2357~2362 (2000)
- Margherio RR, "Removal of epimacular membranes", Ophthalmology, 92, pp.1075~1083 (1985)
- 권순일, "The Clinical Course of the Idiopathic Epiretinal Membrane After Surgery", Korean Journal of Ophthalmology, 23(4), pp.249~252 (2009), 대한안과학회
- Rice TA, "Prognostic factors in vitrectomy for epiretinal membranes of the macula", Ophthalmology, 93, pp.602~610 (1986)
- Vujosevic S, "Diabetic macular edema: correlation between microperimetry and optical coherence tomography findings", Invest Ophthalmol Vis Sci, 47, pp.3044~3051 (2006)
- 황덕진, "특발성 망막전막의 유리체 절제술 후 시력과 망막두께의 장기변화 관찰", 대한안과학회지, 53(3), pp.434~439 (2012), 대한안과학회
- van Velthoven ME, "Recent developments in optical coherence tomography for imaging the retina", Prog Retin Eye Res, 26, pp.57~77 (2007)
- Ko TH, "Comparison of ultrahighand standard-resolution optical coherence tomography for imaging macular pathology", Ophthalmology, 112(1922), pp.e1~e15 (2005)
- Schmidt-Erfurth U, "Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases", Invest Ophthalmol Vis Sci, 46, pp.3393~3402 (2005)
- Karacorlu M, "Correlation of retinal sensitivity with visual acuity and macular thickness in eyes with idiopathic epimacular membrane", Int Ophthalmol, 30, pp.285~290 (2010)
- Oster SF, "Disruption of the photoreceptor inner segment", outer segment layer on spectral domain-optical coherence tomography is a predictor of poor visual acuity in patients with epiretinal membranes, 2010, pp.30, 713~718
- 이지은, "황반원공 수술 후 빛간섭단층촬영에서 시수용체층 및 중심와두께와 시력의 상관관계", 대한안과학회지, 47(12), pp.1966~1971 (2006), 대한안과학회
- Oh J, "Photoreceptor inner", outer segment defect imaging by spectral domain OCT and visual prognosis after macular hole surgery, 2010, pp.51, 1651~1658
- Chang LK, "Disruption of the photoreceptor inner segment-outer segment junction in eyes with macular holes", Retina, 28, pp.969~975 (2008)
- Chung H, "Correlation of microperimetry with fundus autofluorescence and spectral-domain optical coherence tomography in repaired macular holes", Am J Ophthalmol, 151, pp.128~136 (2011)
- Ooto S, "Photoreceptor damage and foveal sensitivity in surgically closed macular holes: an adaptive optics scanning laser ophthalmoscopy study", Am J Ophthalmol, 154, pp.174~186 (2012)
- Kim YG, "Analysis of spectral domain optical coherence tomography findings in occult macular dystrophy", Acta Ophthalmol, 89, pp.e52~e56 (2011)
- Lim JW, "Assessment of macular function by multifocal electroretinography following epiretinal membrane surgery with internal limiting membrane peeling", Clin Ophthalmol, 4, pp.689~694 (2010)
- 강재훈, "특발성 망막전막 제거술 전후의 다국소 망막전위도 비교에 대한 연구", 대한안과학회지, 49(1), pp.104~110 (2008), 대한안과학회
- Okada K, "Correlation of retinal sensitivity measured with fundus-related microperimetry to visual acuity and retinal thickness in eyes with diabetic macular edema", Eye (Lond), 20, pp.805~809 (2006)
- Springer C, "Central serous chorioretinopathy-- retinal function and morphology: microperimetry and optical coherence tomography", Ophthalmologe, 103, pp.791~797 (2006)
- Amari F, "Predicting visual outcome after macular hole surgery using scanning laser ophthalmoscope microperimetry", Br J Ophthalmol, 85, pp.96~98 (2001)
- Klein R, "The epidemiology of epiretinal membranes", Trans Am Ophthalmol Soc, 92, pp.403~425 (1994)
- Gastaud P, "Ultrastructural findings of epimacular membrane and detached posterior hyaloid in vitreomacular traction syndrome", J Fr Ophtalmol, 23, pp.587~593 (2000)
- Michels RG, "Vitreous surgery for macular pucker", Am J Ophthalmol, 92, pp.628~639 (1981)
- Inoue M, "Preoperative inner segment", outer segment junction in spectral-domain optical coherence tomography as a prognostic factor in epiretinal membrane surgery, 2011, pp.31, 1366~1372
- Frisén L, "Micropsia and visual acuity in macular edema. A study of the neuro-retinal basis of visual acuity", Albrecht Von Graefes Arch Klin Exp Ophthalmol, 210, pp.69~77 (1979)
- Ehrlich R, "Visual function following photodynamic therapy for central serous chorioretinopathy: a comparison of automated macular microperimetry versus best-corrected visual acuity", Clin Experiment Ophthalmol, 40, pp.e32~e39 (2012)
- Suh MH, "Associations between macular findings by optical coherence tomography and visual outcomes after epiretinal membrane removal", Am J Ophthalmol, 147, pp.473~480 (2009)
- Tso MO, "Animal modeling of cystoid macular edema", Surv Ophthalmol, 28(Suppl), pp.512~519 (1984)
- Pesin SR, "Vitrectomy for premacular fibroplasia. Prognostic factors, long-term follow-up, and time course of visual improvement", Ophthalmology, 98, pp.1109~1114 (1991)
- Inoue M, "Inner segment", outer segment junction assessed by spectral-domain optical coherence tomography in patients with idiopathic epiretinal membrane, 2010, pp.150, 834~839
- Mitamura Y, "Correlation of visual recovery with presence of photoreceptor inner", outer segment junction in optical coherence images after epiretinal membrane surgery, 2009, pp.93, 171~175
- Rohrschneider K, "Use of fundus perimetry (microperimetry) to quantify macular sensitivity", Prog Retin Eye Res, 27, pp.536~548 (2008)
- Sunness JS, "Landmark-driven fundus perimetry using the scanning laser ophthalmoscope", Invest Ophthalmol Vis Sci, 36, pp.1863~1874 (1995)
- Michalewski J, "Morphologically functional correlations of macular pathology connected with epiretinal membrane formation in spectral optical coherence tomography (SOCT)", Graefes Arch Clin Exp Ophthalmol, 245, pp.1623~1631 (2007)
- Kinoshita T, "Morphologic differences in epiretinal membranes on ocular coherence tomography as a predictive factor for surgical outcome", Retina, 31, pp.1692~1698 (2011)
