빛간섭단층촬영으로 측정한 정상 소아청소년의 시신경유두 지표
Optic Nerve Head Parameters of Healthy Children as Measured by Optical Coherence Tomography
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목적: 빛간섭단층촬영으로 측정한 정상 소아청소년의 시신경유두 지표를 알아보고자 한다. 대상과 방법: 5세에서 17세의 소아청소년을 대상으로 스텍트럼영역 빛간섭단층촬영을 이용하여 시신경유두 주위 영역을 스캔하였다. 빛단섭단층촬영 장비가 자동으로 산출하는 시신경유두 지표인 시신경테 면적, 시신경유두 면적, 시신경유두 함몰비, 시신경유두패임부피의 분포를 알아보고, 굴절값 및 나이가 측정치에 미치는 영향을 분석하였다. 결과: 총 352명의 352안이 포함되었고, 평균 나이는 9.7 ± 3.6세였다. 평균 시신경테 면적, 시신경유두 면적, 시신경유두 함몰비, 시신경유두패임 부피는 1.51 ± 0.27 mm2, 2.07 ± 0.39 mm2, 0.47 ± 0.16, 0.163 ± 0.148 mm3였다. 평균 시신경테 면적, 시신경유두면적, 시신경유두 함몰비를 나이에 따라 세부 구분하였을 때, 5-8세는 1.58 ± 0.29 mm2, 2.18 ± 0.35 mm2, 0.48 ± 0.17, 9-12세는1.46 ± 0.24 mm2, 2.04 ± 0.43 mm2, 0.49 ± 0.15, 13-17세는 1.46 ± 0.22 mm2, 1.94 ± 0.35 mm2, 0.44 ± 0.18이었다. 시신경테면적은 근시가 심할수록, 나이가 많을수록 더 작았다(p<0.05). 결론: 건강한 소아청소년에서 빛간섭단층촬영으로 측정한 평균 시신경테 면적은 1.51 mm2, 시신경유두 면적은 2.07 mm2, 시신경유두함몰비는 0.47이었고 나이와 굴절값에 따라 다른 분포를 보였다.
Abstract
Purpose: To investigate optic nerve head (ONH) parameters as measured using optical coherence tomography (OCT) in healthy children. Methods: Peripapillary areas were scanned by spectral-domain OCT in healthy eyes of children aged 5–17 years. ONH parameters were automatically determined by OCT, including the rim area, disc area, cup-to-disc ratio, and cup volume. The effects of age and refractive error on ONH parameters were evaluated. Results: A total of 352 eyes of 352 subjects (mean age: 9.7 ± 3.6 years) were enrolled. The mean rim area, disc area, cup-to-disc ratio, and cup volume was 1.51 ± 0.27 mm2, 2.07 ± 0.39 mm2, 0.47 ± 0.16, and 0.163 ± 0.148 mm3, respectively. The mean rim area, disc area, cup-to-disc ratio by age was 1.58 ± 0.29 mm2, 2.18 ± 0.35 mm2, and 0.48 ± 0.17 in 5- to 8-year-olds; 1.46 ± 0.24 mm2, 2.04 ± 0.43 mm2, and 0.49 ± 0.15 for 9- to 12-year-olds; and 1.46 ± 0.22 mm2, 1.94 ± 0.35 mm2, and 0.44 ± 0.18 for 13- to 17-year-old. Higher myopia and older age were associated with a smaller rim area (p < 0.05). Conclusions: The mean rim area, disc area, and cup-to-disc ratio as measured using OCT in healthy children were 1.51 mm2, 2.07 mm2, and 0.47, respectively. ONH parameters were significantly affected by age and refractive error.
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