Differences between Non-arteritic Anterior Ischemic Optic Neuropathy and Open Angle Glaucoma with Altitudinal Visual Field Defect
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Purpose: To investigate the differences in retinal nerve fiber layer (RNFL) change and optic nerve head parametersbetween non-arteritic anterior ischemic optic neuropathy (NAION) and open angle glaucoma (OAG) withaltitudinal visual field defect. Methods: Seventeen NAION patients and 26 OAG patients were enrolled prospectively. The standard visualfield indices (mean deviation, pattern standard deviation) were obtained from the Humphrey visual field testand differences between the two groups were analyzed. Cirrus HD-OCT parameters were used, including opticdisc head analysis, average RNFL thickness, and RNFL thickness of each quadrant. Results: The mean deviation and pattern standard deviation were not significantly different between the groups. In the affected eye, although the disc area was similar between the two groups (2.00 ± 0.32 and 1.99 ± 0.33mm2, p = 0.586), the rim area of the OAG group was smaller than that of the NAION group (1.26 ± 0.56 and 0.61± 0.15 mm2, respectively, p < 0.001). RNFL asymmetry was not different between the two groups (p = 0.265),but the inferior RNFL thickness of both the affected and unaffected eyes were less in the OAG group than inthe NAION group. In the analysis of optic disc morphology, both affected and unaffected eyes showed significantdifferences between two groups. Conclusions: To differentiate NAION from OAG in eyes with altitudinal visual field defects, optic disc headanalysis of not only the affected eye, but also the unaffected eye, by using spectral domain optical coherencetomography may be helpful.
Abstract
Purpose: To investigate the differences in retinal nerve fiber layer (RNFL) change and optic nerve head parametersbetween non-arteritic anterior ischemic optic neuropathy (NAION) and open angle glaucoma (OAG) withaltitudinal visual field defect. Methods: Seventeen NAION patients and 26 OAG patients were enrolled prospectively. The standard visualfield indices (mean deviation, pattern standard deviation) were obtained from the Humphrey visual field testand differences between the two groups were analyzed. Cirrus HD-OCT parameters were used, including opticdisc head analysis, average RNFL thickness, and RNFL thickness of each quadrant. Results: The mean deviation and pattern standard deviation were not significantly different between the groups. In the affected eye, although the disc area was similar between the two groups (2.00 ± 0.32 and 1.99 ± 0.33mm2, p = 0.586), the rim area of the OAG group was smaller than that of the NAION group (1.26 ± 0.56 and 0.61± 0.15 mm2, respectively, p < 0.001). RNFL asymmetry was not different between the two groups (p = 0.265),but the inferior RNFL thickness of both the affected and unaffected eyes were less in the OAG group than inthe NAION group. In the analysis of optic disc morphology, both affected and unaffected eyes showed significantdifferences between two groups. Conclusions: To differentiate NAION from OAG in eyes with altitudinal visual field defects, optic disc headanalysis of not only the affected eye, but also the unaffected eye, by using spectral domain optical coherencetomography may be helpful.
참고문헌 (15)
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