Comparison of Serum Cortisol and Testosterone Levels in Acute and Chronic Central Serous Chorioretinopathy
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Purpose: To compare the levels of serum cortisol and testosterone in acute and chronic central serous chorioretinopathy(CSC). Methods: Serum cortisol and testosterone levels in 30 patients with either acute or chronic CSC were evaluatedusing chemiluminescent immunoassay. Results: The mean age was 42.43 ± 6.37 years (range, 32 to 56 years). The mean 8:00 to 9.00 a.m. serum cortisollevel was 12.61 ± 4.74 μg/dL (range, 6.58 to 27.42 μg/dL). The mean serum testosterone level was 5.88± 1.57 ng/dL (range, 2.81 to 9.94 ng/dL). The mean visual acuity was 20 / 65.07 ± 40.56 (range, 20 / 25 to 20/ 200). There was no statistically significant difference in the mean levels of serum cortisol and testosteronebetween the acute and chronic cases (p > 0.05), but there was a statistically significant difference in the meanpresenting visual acuity in the two groups (p < 0.05). Conclusions: All except one patient in the acute group had normal levels of serum cortisol. Testosterone levelswere within the normal range in both the acute and chronic cases of CSC. There is unlikely to be any statisticallysignificant difference in the mean levels of serum cortisol and testosterone between the acute and chroniccases, but there may be a statistically significant difference in the mean presenting visual acuity in thesegroups.
Abstract
Purpose: To compare the levels of serum cortisol and testosterone in acute and chronic central serous chorioretinopathy(CSC). Methods: Serum cortisol and testosterone levels in 30 patients with either acute or chronic CSC were evaluatedusing chemiluminescent immunoassay. Results: The mean age was 42.43 ± 6.37 years (range, 32 to 56 years). The mean 8:00 to 9.00 a.m. serum cortisollevel was 12.61 ± 4.74 μg/dL (range, 6.58 to 27.42 μg/dL). The mean serum testosterone level was 5.88± 1.57 ng/dL (range, 2.81 to 9.94 ng/dL). The mean visual acuity was 20 / 65.07 ± 40.56 (range, 20 / 25 to 20/ 200). There was no statistically significant difference in the mean levels of serum cortisol and testosteronebetween the acute and chronic cases (p > 0.05), but there was a statistically significant difference in the meanpresenting visual acuity in the two groups (p < 0.05). Conclusions: All except one patient in the acute group had normal levels of serum cortisol. Testosterone levelswere within the normal range in both the acute and chronic cases of CSC. There is unlikely to be any statisticallysignificant difference in the mean levels of serum cortisol and testosterone between the acute and chroniccases, but there may be a statistically significant difference in the mean presenting visual acuity in thesegroups.
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