Physicochemical properties and antibacterial studies of hydroxyapatite scaffold extracted from indonesian limestone
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This research successfully fabricated scaffolds with hydroxyapatite (HA) from limestone and with HA coating using the gasfoaming method. HA coating uses the addition of cinnamon oil in HA from limestone and impacts the scaffold’s antibacterialproperties. Scaffold fabrication uses the gas foaming method with a drying time of 30 minutes and 0.9 grams of HA. Thefabricated scaffold is then characterized using an X-ray diffractometer (XRD), Fourier Transform Infra-Red (FTIR), andScanning Electron Microscopy (SEM). Then, the antibacterial analysis of scaffolds using the diffusion method. Scaffolds fromHA coating have smaller crystal sizes, fewer agglomerations, smaller particle sizes, and a more even distribution and size ofpores. Scaffolds with HA coating have higher porosity than scaffolds with HA only. HA coating shows that adding cinnamonoil as an antibacterial agent can inhibit strong bacteria for S. aureus bacteria with an inhibition zone size of 11 mm.
Abstract
This research successfully fabricated scaffolds with hydroxyapatite (HA) from limestone and with HA coating using the gasfoaming method. HA coating uses the addition of cinnamon oil in HA from limestone and impacts the scaffold’s antibacterialproperties. Scaffold fabrication uses the gas foaming method with a drying time of 30 minutes and 0.9 grams of HA. Thefabricated scaffold is then characterized using an X-ray diffractometer (XRD), Fourier Transform Infra-Red (FTIR), andScanning Electron Microscopy (SEM). Then, the antibacterial analysis of scaffolds using the diffusion method. Scaffolds fromHA coating have smaller crystal sizes, fewer agglomerations, smaller particle sizes, and a more even distribution and size ofpores. Scaffolds with HA coating have higher porosity than scaffolds with HA only. HA coating shows that adding cinnamonoil as an antibacterial agent can inhibit strong bacteria for S. aureus bacteria with an inhibition zone size of 11 mm.
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