PET/CT에서 Phantom을 이용한 Fluorine-18, Gallium-68 방사성 핵종의 PET 영상 평가
Evaluation of PET Image for Fluorine-18 and Gallium-68 using Phantom in PET/CT
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초록
The purpose of this study is to compare PET imaging performance with Fluorine-18 (18F) and Gallium-68 (68Ga) for influence of physical properties of PET tracer. Measurement were performed on a Siemens Biograph mCT64 PET/CT scanner using NEMA IEC body phantom and Flangeless Esser PET phantom containing filled with 18F and 68Ga. Emission scan duration(ESD) was set to 1, 2, 3, 4 and 5min/bed for 68Ga and 1min/bed for 18F. The PET image were evaluated in terms of contrast, spatial resolution. Under same condition, The percentage of contrast recovery measured in the phantom ranged from 16.88% to 72.56% for 68Ga and from 27.51% to 74.43% for 18F and The FWHM value to evaluate spatial resolution was 10.96 ㎜ for 68Ga and 9.19 ㎜ for 18F. For this study, 18F produces better image contrast and spatial resolution than 68Ga due to higher positron yield and lower positron energy (18F: 96.86%, 633.5 keV, 68Ga: 88.9%, 1899 keV), The physical properties of PET tracer effect on the PET image. 68Ga image applying ESD of 3, 4, 5min/bed were showed similar to 18F image with ESD of 1min/bed. This study suggests that increasing ESD for acquiring 68Ga PET image seem to be similar to 18F image.
Abstract
The purpose of this study is to compare PET imaging performance with Fluorine-18 (18F) and Gallium-68 (68Ga) for influence of physical properties of PET tracer. Measurement were performed on a Siemens Biograph mCT64 PET/CT scanner using NEMA IEC body phantom and Flangeless Esser PET phantom containing filled with 18F and 68Ga. Emission scan duration(ESD) was set to 1, 2, 3, 4 and 5min/bed for 68Ga and 1min/bed for 18F. The PET image were evaluated in terms of contrast, spatial resolution. Under same condition, The percentage of contrast recovery measured in the phantom ranged from 16.88% to 72.56% for 68Ga and from 27.51% to 74.43% for 18F and The FWHM value to evaluate spatial resolution was 10.96 ㎜ for 68Ga and 9.19 ㎜ for 18F. For this study, 18F produces better image contrast and spatial resolution than 68Ga due to higher positron yield and lower positron energy (18F: 96.86%, 633.5 keV, 68Ga: 88.9%, 1899 keV), The physical properties of PET tracer effect on the PET image. 68Ga image applying ESD of 3, 4, 5min/bed were showed similar to 18F image with ESD of 1min/bed. This study suggests that increasing ESD for acquiring 68Ga PET image seem to be similar to 18F image.
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