혈청 Creatine Kinase효소분석 표준화에 관한 연구

Abstract

In European contrues or Japan they made an attempt for the standardization of assays in AST, ALT, ALP, CK, LD and GGT 10 years ago. For the actualization of the trial, they managed to succeeded in development of cretified reference material and enzyme reference material. And they are now forecasting the unification of test results produced differently under the respective situatons. Then, though the highly developed communication system, someone can access any test results whenever of whereever only if they want to. It means that we can expect much greater improvements in medical services through the information exchanges. In this study the authors tried to ascertain the nterchangeability comparing the pbtained results of the CK tests between two general hospitals. Fortunately, the data got in the internal QC programs came to fall within the norma tolerances. The reference intervals for the CK test were differint according to the chosen reagents and the results from the pooled sear were also shown differently each other. Howere, from the two hospitals, we could get glucose K factors, upon which the measurements were obtained and compared. Using K factors we measured the CKs, then we mulply the CK values by corretion cefficients. We could found the the two results were showing good coincidedne in the comparison. The main purpose of the standardization o f edzyme assays is the creation of a new unified value which can be expressed differently otherwise. Using the standardized values we can exploit the data everywhere, reduce the medical costs from repeated or duplicated tests, save the foreign exchanges preventing the diversification of import connections.