임상검체에서 분리한 ATB32C를 이용한 Trichosporon 균속의 새로운 species 동정

Abstract

Trichosporon species are a medically important genus that includes the causative agents of both deep-seated and superficial infections. In the past investigators had considered Trichosporon beigelii to be the asexual state white piedra. They placed Trichosporon cutaneum as a later synonym of T. beigelii and listed T. beigelii as the type species of the genus Trichosporon. The caustive agent of trichosporonosis was belived to be T. cutaneum (same as T. beigelii), but recent taxonomic research has indicated that six species, T. asahii, I asteroides, T. cutaneum, T. inkin, T. mucoides, and T. ovoides, are associated with the infection. A few reports have proposed that T. beigelii is a pathogen of onychomycosis in Korea. In the present study, we describe a yeast biochemical test of ID 32C(bioMérieux, France) approach for detection of all species in the genus Trichopsoron including the causative agent of onychomycosis. The strains used in this study are 58 strains isolated from patients of tertiary Hospital in Seoul. T. asahii, T. mucoides, and T. inkin are 82.8%, 13.8%, and 3.4% respectively. The correct name for the main agent of onychomycosis is T. asahii. The name T. beigelii is considered as of doubtful identity. We suggest that T. asahii might be a coomon pathogen of onychomycosis in Korea. We contructed a readily used and accurate identification system for all of the species in the genus Trichosporon, including the six medically relevant species, based on additional analysis of biochemical test and slide culture.