황금추출물의 항산화와 멜라닌생성 저해 효과
Effect of Antioxidation and Inhibition of Melanogenesis from Scutellaria Baicalensis Extract
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초록
Melanigenesis with basic cosmetic ingredients was investigated. skin lightening is one of the most importanteffect of functinal cosmetics, especially for the asian women. In this work, the extract of Scutellaria baicalensisand its key flavonoids such as baicalin, baicalein and wogonin were studied to characterize as a cosmeticingredient. Anitoxidant activity of Scutellaria baicalensis extract was not very high but was high enough to beemployed in cosmetics. When the Scutellaria baicalensis extract and the flavonoids were added to the culturemedia of B16F10 melanoma, the melanin production was inhibited concentration dependently and this effectwas enough to be used as whitening material of cosmetics. Scutellaria baicalensis extract and the flavonoidswere melaninmeasurement α-MSH inhibited concentration dependently. Baiclain, baicalein, wogonin 1 μM whencompared with the control group there was significant.(p <0.01). The results of this flavonoid know that excellentwhitening effect, and the next natural whitening ingredients that can be used in navigation could confirm that.
Abstract
Melanigenesis with basic cosmetic ingredients was investigated. skin lightening is one of the most importanteffect of functinal cosmetics, especially for the asian women. In this work, the extract of Scutellaria baicalensisand its key flavonoids such as baicalin, baicalein and wogonin were studied to characterize as a cosmeticingredient. Anitoxidant activity of Scutellaria baicalensis extract was not very high but was high enough to beemployed in cosmetics. When the Scutellaria baicalensis extract and the flavonoids were added to the culturemedia of B16F10 melanoma, the melanin production was inhibited concentration dependently and this effectwas enough to be used as whitening material of cosmetics. Scutellaria baicalensis extract and the flavonoidswere melaninmeasurement α-MSH inhibited concentration dependently. Baiclain, baicalein, wogonin 1 μM whencompared with the control group there was significant.(p <0.01). The results of this flavonoid know that excellentwhitening effect, and the next natural whitening ingredients that can be used in navigation could confirm that.
참고문헌 (30)
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