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2004년 진주 지역 초등학생 인두배양의 베타 용혈성 연쇄구균의 분포

Distribution of Beta-Hemolytic Streptococci of Throat Culture of Elementary School Children in Jinju Area, 2004

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배경:세균성 인두염의 가장 흔한 원인 균인 A군 연쇄구균(group A streptococci, GAS)의 보균자 조사는 그 지역의 GAS 세균의 역학적 특성을 살펴보는데 중요하다. 저자들은 진주 지역의 네 개 초등학교의 학생들을 대상으로 인두배양을 시행하여 세균학적 특성을 살펴보았다. 방법:2004년 10월에서 12월까지 경남 진주 지역 읍면지역에 위치한 두 개의 초등학교와 시내에 위치 한 두 개 초등학교를 방문하여 상기도 감염 증상이 없는 2,351명(남 1,311명, 여 1,040명)에 대하여 인두배양을 시행하였다. Bacitracin 디스크(0.04 U)와 라텍스응집법(Seroiden Strepto Kit, Eiken)으로 베타용혈성 연쇄구균(beta-hemolytic streptococci, BHS)을 동정하였다. 결과:총 2,351명의 초등학생 인두배양에서 443명(18.8%)으로부터 BHS가 분리되었다. 라텍스 응집시험으로 동정한 결과 443개의 BHS 중 A군 84.9%, C군 5.9%, B군 4.7%, G군 3.6% 및 비A,B,C,G군 0.9% 순으로 동정 되었다. 각 학교별 GAS 분리율은 읍면지역의 초등학교가 18.6-21.9%로서 시내 초등학교의 12.5%-15.0%보다 유의하게 높았다. 결론:2004년 진주 지역 초등학생의 인두배양에서 BHS 분리율은 18.8%이었으며 그 중 A군이 84.9% 이었고, 비A군 중에서는 C군이 가장 많았다. 연령이나 성별에 따라 GAS 분리율에 차이는 없었지만, 시내보다 읍면에 위치한 초등학교에서 GAS 분리율이 유의하게 높았다.

Abstract

Background: The carrier study of group A streptococci (GAS), the most common cause of bacterial pharyngitis, is important to understand the epidemiology of GAS in the region. The authors performed throat cultures from the children of four elementary schools in Jinju area to investigate current microbiological characteristics in this area. Methods: Throat cultures were taken from 2,351 healthy elementary school children (male 1,311 and female 1,040) from October through December, 2004. Two schools are located in rural areas, while the other two schools are in Jinju city. Beta-hemolytic streptococci (BHS) were identified with bacitracin disk (0.04 U) and latex agglutination test (Seroiden Strepto Kit, Eiken). Results: Four-hundred forty-three (18.8%) yielded BHS from 2,351 school children. Serogrouping revealed 84.9% of group A, 5.9% of group C, 4.7% of group B, 3.6% of group G, and 0.9% of nongroup A, B, C, G in a decreasing order. Isolation rate of GAS was similar between girls and boys. Children of elementary schools in rural areas showed significantly higher isolation rates (18.6-21.7%) compared to those (12.5-12.7%) in urban areas. Conclusion: The isolation rate of BHS was 18.8% in Jinju area, 2004. Group A was 84.9% and group C was next common. Although the isolation rate of GAS was similar by age or sex, it showed a significant difference by the location of the schools.

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