Microbiological Characteristics of Throat Cultures from School Children in Jinju, 2006
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배경: A군 연쇄구균(group A streptococci, GAS)는 소아에서 인두염의 중요 원인균이다. 진주 지역의 건강한 초등학생으로 부터 인두배양을 시행하여 세균학적 특성을 살펴보고, 과거의 결과와 비교하였다. 방법: 2006년 진주시내 3곳의 초등학교에서1,402명의 학생들을 대상으로 인두배양을 실시하였다. 베타용혈 연쇄구균은 bacitracin 디스크와 라텍스 응집법(Seroiden Strepto Kit, Eiken, Tokyo, Japan)으로 동정하였다. 결과: 베타용혈성 연쇄구균은 216명(15.4%)에서 양성이었고, GAS는 149명(10.6%)에서 양성이었다. GAS 양성률은 2004년의 16.0%와 2002년의 16.9%에 비해서 유의하게 감소하였다(P＜0.05). 베타용혈성 연쇄구균 중 A군이 차지하는 비율은 69.0%로서, 역시 2004년의 84.9%, 2002년의 83.8%에 비해서 유의하게 감소하였다(P＜0.05). 모든 1학년 학생들에서 베타 용혈성 연쇄구균과 GAS는 음성이었다. 남학생(10.4%)과 여학생(10.9%)의 GAS 분리율은 비슷하였다. 결론: 2006년에 시행한 인두배양에서 베타용혈성 연쇄구균이나 GAS 양성률은 과거에 비해서 유의하게 낮아졌다. 흔한 연쇄구균 혈청형에 대한 자연 면역이나 개인 위생 증진에 따른 결과인 것으로 추측할 수 있다.
Abstract
Background: Group A streptococci (GAS) are the most common cause of pharyngitis in children. The streptococci in throat cultures from healthy elementary school children in Jinju were compared with previous results. Methods: Throat cultures were taken from 1,402 healthy school children in 2006. β-hemolytic streptococci (BHS) were identified with a bacitracin disk (0.04 U) and latex agglutination test (Seroiden Strepto Kit, Eiken, Tokyo, Japan). Results: Two-hundred sixteen (15.4%) and 149 (10.6%) cultures grew BHS and GAS, respectively. The isolation rate of GAS was significantly lower than in 2004 (16.0%) or 2002 (16.9%) (P＜0.05). Among BHS, the prevalence of group A strains (69.0%) decreased significantly compared with 2004 (84.9%) and 2002 (83.8%) (P＜0.05). None of the 1st-grade children yielded BHS or GAS. Conclusion: The isolation rates of BHS and GAS from healthy school children were lower in 2006 than in previous years. Natural immunization against the common serotypes or improvement in individual hygiene might have played roles in the reduction of isolations of GAS.
참고문헌 (11)
- Bisno AL, "Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America", Clin Infect Dis, 35, pp.113~125 (2002)
- Bingol-Kologlu M, "Necrotizing fasciitis in children: diagnostic and therapeutic aspects", J Pediatr Surg, 42, pp.1892~1897 (2007)
- 김선주, "emm 유전자형을 이용한 초등학생에서 분리된 A군 연쇄구균의 역학조사", Annals of Laboratory Medicine, 22(6), pp.417~423 (2002), 대한진단검사의학회
- Koh EH, "Distribution of beta-hemolytic streptoccci of throat culture of elementary school children in Jinju area, 2004", Korean J Clin Microbiol, 8, pp.51~56 (2005)
- Lindbaek M, "Clinical symptoms and signs in sore throat patients with large colony variant beta-haemolytic streptococci groups C or G versus group A", Br J Gen Pract, 55, pp.615~619 (2005)
- Kim S, "Epidemiological usefulness of anti-opacity factor antibody screening in schoolchildren", J Clin Microbiol, 39, pp.1316~1318 (2001)
- Prakash K, "Streptococcal throat carriage in school children with special reference to seasonal incidence", Southeast Asian J Trop Med Public Health, 23, pp.705~710 (1992)
- Lee KY, "Seasonal incidence of streptococcal carriers in school children in Korea and its correlationship with streptococcal diseases", Yonsei J Med Sci, 7, pp.126~138 (1974)
- Wannamaker LW, "Perplexity and precision in the diagnosis of streptococcal pharyngitis", Am J Dis Child, 124, pp.352~358 (1972)
- Kim SJ, "Evaluation of streptococcus selective agar (ssA) for recovery of group A streptococci from throat cultures", J Lab Med Qual Assur, 19, pp.185~190 (1997)
- Kim SJ, "Bacteriologic characteristics and serotypings of Streptococcus pyogenes isolated from throats of school children", Yonsei Med J, 41, pp.56~60 (2000)