혈액에서 분리된 Clostridium symbiosum
Clostridium symbiosum Isolated from Blood
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Clostridium symbiosum은 장내 상재균 중의 하나로 면역 저하 등의 위험 인자가 있는 경우 인체에 드물게 감염을 유발한다. 저자들은 혈액에서 C. symbiosum이 분리된 1예를 경험하여 보고하고자 한다. 원격전이가 있는 난소암 환자의 말초삽입형 중심정맥관 혈액의 혐기성 배양 병에서 바늘 끝 크기의 반투명한 집락을 형성하는 아포 무형성 그람 음성 막대균이검출되었다. 이 균은 Vitek II (bioMérieux, France)에 의해 unidentified organism으로 동정이 되지 않았고, 16S rRNA 염기서열 분석 결과 C. symbiosum과 99.4%의 일치율을 보였다. 본 증례는 국내에서 C. symbiosum을 동정한 첫 증례보고이다. [대한임상미생물학회지 2010;13:90-92
Abstract
Clostridium symbiosum was isolated from the blood of a 61-year-old immunocompromised woman who had diagnosed ovarian cancer with multiple metastases and who had developed persistent tachycardia. A blood culture was drawn from the peripherally inserted central catheter, and non-spore-forming gram-negative rods were detected in an anaerobic vial. The organism showed tiny and pinpoint colonies and was unidentified by Vitek II (bioMérieux,France). The 16S rRNA gene sequence showed a 99.4% identity with C. symbiosum. To our knowledge,this represents the first report of C. symbiosum isolation in Korea. (Korean J Clin Microbiol 2010;13:90-92)
참고문헌 (10)
- Blairon L, "A 62-month retrospective epidemiological survey of anaerobic bacteraemia in a university hospital", Clin Microbiol Infect, 12, pp.527~532 (2006)
- Diekema DJ, "Epidemiology and outcome of nosocomial and community-onset bloodstream infection", J Clin Microbiol, 41, pp.3655~4660 (2003)
- 박용정, "최근 임상검체에서의 혐기성 세균 분리 현황 및 혐기성 균혈증의 임상적 특징", Infection and Chemotherapy, 41(4), pp.216~223 (2009), 대한감염학회
- Zahar JR, "Incidence and clinical significance of anaerobic bacteraemia in cancer patients: a 6-year retrospective study", Clin Microbiol Infect, 11, pp.724~729 (2005)
- Wilson JR, "Risk factors for mortality in patients with anaerobic bacteremia", Eur J Clin Microbiol Infect Dis, 23, pp.310~316 (2004)
- Decousser JW, "Clostridium symbiosum as a cause of bloodstream infection in an immunocompetent patient", Anaerobe, 13, pp.166~169 (2007)
- Elsayed S, "Bacteremia caused by Clostridium symbiosum", J Clin Microbiol, 42, pp.4390~4392 (2004)
- The Korean Society for Laboratory Medicine, "Diagnostic Laboratory Medicine. 4th ed", 497~ (2009)
- Johnson MJ, "Techniques for controlling variability in gram staining of obligate anaerobes", J Clin Microbiol, 33, pp.755~758 (1995)
- Woo PC, "Clostridium bacteraemia characterised by 16S ribosomal RNA gene sequencing", J Clin Pathol, 58, pp.301~307 (2005)