본문 바로가기
KERD
논문KCI 등재

Survey of Antimicrobial Resistance of Pharyngeal α-Hemolytic Streptococci among School Children

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

알파용혈성 연쇄구균은 내성 유전자를 폐렴구균에 전달할 수 있다. 건강한 초등학생의 인두에서 분리된 333균주의 알파 용혈성 연쇄구균에 대해 디스크 확산법으로 항생제 감수성 검사를 시행하였다. Erythromycin에 22.2%, clindamycin에 12.0%, cefotaxime에 3.0%의 내성률을 보였다. 한국에서 폐렴구균의 erythromycin 내성률이 70% 이상임을 감안하면, 인두 알파용혈성 연쇄구균은 낮은 내성률을 보였다.

Abstract

α-hemolytic streptococci (AHS) are common normal oropharyngeal flora that can transfer antibiotic-resistance genes to Streptococcus pneumoniae. Reports on antibiotic resistance in AHS from throats are rare in Korea. A total of 333 healthy school children were subjected to recovery of AHS from the throat, and antibiotic susceptibility tests were screened with the disk diffusion method. The rate of resistance to erythromycin was 22.2%, to clindamycin 12.0%, and to cefotaxime 3.0%. Whereas the resistance rate of S. pneumoniae to erythromycin exceeds 70% in Korea, pharyngeal AHS showed low resistance rates.

참고문헌 (11)

  1. Bryskier A, "Vridians group streptococci: a reservoir of resistant bacteria in oral cavities", Clin Microbiol Infect, 8, pp.65~69 (2002)
  2. Cerdá Zolezzi P, "Molecular basis of resistance to macrolides and other antibiotics in commensal viridans group streptococci and Gemella spp. and transfer of resistance genes to Streptococcus pneumoniae", Antimicrob Agents Chemother, 48, pp.3462~3467 (2004)
  3. "Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; seventeenth informational supplement", Wayne, PA; CLSI,, ~, pp.CLSI Document M100-S17 (2007)
  4. Ioannidou S, "Antibiotic resistance rates and macrolide resistance phenotypes of viridans group streptococci from the oropharynx of healthy Greek children", Int J Antimicrob Agents, 17, pp.195~201 (2001)
  5. Aracil B, "Miñambres M, Oteo J, Torres C, Gómez-Garcés JL, Alós JI. High prevalence of erythromycin-resistant and clindamycinsusceptible (M phenotype) viridans group streptococci from pharyngeal samples: a reservoir of mef genes in commensal bacteria", J Antimicrob Chemother, 48, pp.592~594 (2001)
  6. Seppälä H, "Antimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from normal flora", J Antimicrob Chemother, 52, pp.636~644 (2003)
  7. Koh EH, "A decrease in erythromycin resistance rate of Streptococcus pyogenes in 2004 in Jinju", Korean J Clin Microbiol, 9, pp.51~57 (2006)
  8. Doren GV, "Emergence of high rates of antimicrobial resistance among viridans group streptococci in the United States", Antimicrob Agents Chemother, 40, pp.891~894 (1996)
  9. Uh Y, "Antimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from blood culture in Korea", J Antimicrob Chemother, 53, pp.1095~1097 (2004)
  10. Lee NY, "Carriage of antibiotic-resistant pneumococci among Asian children: a multinational surveillance by the Asian Network for Surveillance of Resistant Pathogens (ANSORP)", Clin Infect Dis, 32, pp.1463~1469 (2001)
  11. Waites KB, "Dissemination of macrolide-resistant Streptococcus pneumoniae isolates containing both erm(B) and mef(A) in South Korea", J Clin Microbiol, 41, pp.5787~5791 (2003)

관련 논문AI추천

이 간행물의 다른 논문 (12건)