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Ortho-phenylphenol을 주성분으로 하는 훈증소독제의 돼지열병바이러스와 돼지생식기호흡기증후군바이러스에 대한 살바이러스 효과

Virucidal efficacy of a fumigant containing orth-phenylphenol against classical swine fever virus and porcine reproductive and respiratory syndrome virus

이후장|정지윤|김석|박은기|차춘남|유창열
한국동물위생학회 (THE KOREAN SOCIETY OF VETERINARY SERVICE)|2016.06|한국동물위생학회지|제39권 제2호|pp. 117-124

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키워드

FumigationOrtho-phenylphenolClassical swine fever virusVirucidal efficacy
주제분류수의학

초록

In this study, the virucidal efficacy of a fumigant containing 20% ortho-phenylphenol against classical swine fever virus (CSFV) and porcine reproductive and respiratory syndrome virus (PRRSV) was examined. After each carrier deposited with CSFV and PRRSV suspensions was exposed to the fumi-gant in a 25-m3 test room for 15 h, all carriers were neutralized and diluted, and each diluted suspension was inoculated into each proper cell line. After incubation, CSFV and PRRSV viability in each cell line was examined and 50% tissue culture infectious dose (TCID50)/mL was calculated. In the results, the concentration of viable virus in all of pathogen control-carriers was more than 2×105 TCID50/mL, and there were no cytotoxicity in all of toxicity control-carriers. In addition, the fumigant inactivated ≥4.8 log10(TCID50/mL) of both CSFV and PRRSV. These findings will be useful for preventing the spread of CSFV and PRRSV infection.

Abstract

In this study, the virucidal efficacy of a fumigant containing 20% ortho-phenylphenol against classical swine fever virus (CSFV) and porcine reproductive and respiratory syndrome virus (PRRSV) was examined. After each carrier deposited with CSFV and PRRSV suspensions was exposed to the fumi-gant in a 25-m3 test room for 15 h, all carriers were neutralized and diluted, and each diluted suspension was inoculated into each proper cell line. After incubation, CSFV and PRRSV viability in each cell line was examined and 50% tissue culture infectious dose (TCID50)/mL was calculated. In the results, the concentration of viable virus in all of pathogen control-carriers was more than 2×105 TCID50/mL, and there were no cytotoxicity in all of toxicity control-carriers. In addition, the fumigant inactivated ≥4.8 log10(TCID50/mL) of both CSFV and PRRSV. These findings will be useful for preventing the spread of CSFV and PRRSV infection.

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