천궁(Cnidium officinale Makino) 지상부 추출물의 항산화 활성 평가
Evaluation of Antioxidant Activity of the Extracts from the Aerial parts of Cnidium officinale Makino
2
조회
0
다운로드
48
인용
0
참고문헌
키워드
초록
In order to obtain basic data for utilization of the aerial parts of Cnidium officinale Makino (APCO), the antioxidant properties of the aerial parts and rhizomes of C. officinale were measured using DPPH and ABTS radicals, and nitrite scavenging assays. The ethyl acetate (EA) fraction prepared from the aerial parts of APCO showed the strongest antioxidant activities, and contained high level of total phenolic compounds (325.81 ㎎TE/g) and flavonoids (259.16 ㎎RE/g). The concentrations for 50% reductions (RC50) values of the DPPH and ABTS radicals, and nitrite by the EA fraction of APCO were 11.27 ㎍/㎖, 14.34 ㎍/㎖, and 10.26 ㎍/㎖, respectively. APCO exhibited approximately 3-9 times higher antioxidant activity than rhizomes of C. officinale. The antioxidant capacities of APCO were positively correlated with its total phenolic contents. Therefore, it was concluded that the aerial parts of C. officinale can be a useful and cost-effective source of natural antioxidant for food or cosmetics.
Abstract
In order to obtain basic data for utilization of the aerial parts of Cnidium officinale Makino (APCO), the antioxidant properties of the aerial parts and rhizomes of C. officinale were measured using DPPH and ABTS radicals, and nitrite scavenging assays. The ethyl acetate (EA) fraction prepared from the aerial parts of APCO showed the strongest antioxidant activities, and contained high level of total phenolic compounds (325.81 ㎎TE/g) and flavonoids (259.16 ㎎RE/g). The concentrations for 50% reductions (RC50) values of the DPPH and ABTS radicals, and nitrite by the EA fraction of APCO were 11.27 ㎍/㎖, 14.34 ㎍/㎖, and 10.26 ㎍/㎖, respectively. APCO exhibited approximately 3-9 times higher antioxidant activity than rhizomes of C. officinale. The antioxidant capacities of APCO were positively correlated with its total phenolic contents. Therefore, it was concluded that the aerial parts of C. officinale can be a useful and cost-effective source of natural antioxidant for food or cosmetics.
참고문헌 (24)
- Blios MS, "Antioxidant determination by the use of a stable free radical", Nature, 26, pp.1199~1203 (1958)
- Hae-Yeon Choi, "Antioxidant Activity of the Various Extracts from Different Parts of Lotus (Nelumbo nucifera Gaertner)", Food Science and Biotechnology, 18(4), pp.1051~1054 (2009), 한국식품과학회
- Choi HS, "Constituents of the essential oil of Cnidium officinale Makino,a Korean medicinal plant", Flavour and Fragrance Journal, 17, pp.49~53 (2002)
- 최소라, "이용부위 및 채취시기에 따른 꾸지뽕나무 메탄올 추출물의 항산화성", 한국약용작물학회지, 17(2), pp.115~120 (2009), 한국약용작물학회
- Gray JI, "Inhibition of N-nitrosamine formation in model food system", Journal of Food Science, 40, pp.981~982 (1975)
- 허진선, "참당귀 잎, 줄기혼합물과 뿌리 추출물의 생리활성물질 및 그 활성작용", 생명과학회지, 20(5), pp.750~759 (2010), 한국생명과학회
- 장상훈, "수확시기별, 부위별 선학초의 폴리페놀함량 및 DPPH 라디컬 소거능의 변화", 한국약용작물학회지, 16(6), pp.397~401 (2008), 한국약용작물학회
- Jeong JB, "Protective effect of the extracts from Cnidium officinale against oxidative damage induced by hydrogen peroxide via antioxidant effect", Food and Chemical Toxicology, 47, pp.525~529 (2009)
- 정동선, "천궁(Cnidium officinale Makino) 지상부(잎과 줄기) 추출물의 항균활성", 한국미생물·생명공학회지, 35(1), pp.30~35 (2007), 한국미생물·생명공학회
- Kim SK, "Essential oil content and composition of aromatic constituents in leaf of Saururus chinensis,Angelica dahurica and Cnidium officinale", Korean Journal of Medicinal Crop Science, 6, pp.299~304 (1998)
- Kim JM, "Ethyl acetate soluble fraction of Cnidium officinale Makino inhibits neuronal cell death by reduction of excessive nitric oxide production in lipopolysaccharide-treated rat hippocampal slice cultures and microglia cells", Journal of Pharmacological Science, 92, pp.74~78 (2003)
- Kobayashi M, "Components of Cnidium officinale Makino; occurrence of pregnenolone,coniferylferulate,ferulate and hydroxylphthalides", Chemical and Pharmaceutical Bulletin, 32, pp.3770~3773 (1984)
- Kwak DH, "Antiangiogenic activities of Cnidium officinale Makino and Tabanus bovinus", Journal of Ethnopharmacology, 81, pp.373~379 (2002)
- Kwon JH, "Acaricidal activity of butylidenephthalide identified in Cnidium officinale rhizome against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae)", Journal of Agricultural and Food Chemistry, 50, pp.4479~4483 (2002)
- 권지웅, "약용식물 추출물로부터 항상화활성 탐색", 생약학회지, 39(2), pp.155~163 (2008), 한국생약학회
- Lee CB, "Encyclopedia of Korean plants", pp.583~ (1985), HyangMunSa
- 이지혜, "천궁(Cnidium officinale)의 휘발성 향기성분 및 유리기 소거활성", 한국식품과학회지, 34(2), pp.330~338 (2002), 한국식품과학회
- Lee SY, "Phthalide content of Cnidium rhizome", Korean Journal of Pharmacognosy, 21, pp.69~73 (1990)
- Nam KS, "Effect of Cnidii rhizoma on proliferation of breast cancer cell, nitric oxide production and ornithine decarboxylase activity", Korean Journal of Pharmacology, 35, pp.283~287 (2004)
- NFRI, "Manuals of quality characteristic analysis for food quality evaluation (2)", pp.61~ (1990), National Food Research Institute
- Re R, "Antioxidant activity applying and improved ABTS radical cation decolorization assay", Free Radical Biology and Medicine, 26, pp.1231~1237 (1999)
- Tsukamoto T, "Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila meanogaster", Journal of Agricultural and Food Chemistry, 53, pp.5549~5553 (2005)
- 우정향, "구절초와 남구절초의 항산화 효과에 미치는 수확시기의 영향", 한국자원식물학회지, 21(2), pp.128~133 (2008), 한국자원식물학회
- Yi EJ, "Control of citrus blue mold and chili pepper anthracnose by ligustilide, and antifungal compound from Cnidium officinale Makino", 석사, pp.2004
