Effect of drying temperature on the level of pharmacological compounds in the rhizome of Cnidium officinale Makino
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The rhizome of Cnidium officinale Makino (COM) is known for its medicinal properties due to its pharmacological activity. Typically, it is thermally dried after harvesting before being processed into suitable final products. However, because thermal drying affects the levels of thermolabile compounds in COM rhizomes, suitable drying conditions are necessary to ensure the quality of the final product. In this study, we evaluated the effects of drying temperatures (30-70℃) on the levels of pharmacological and antioxidant compounds in COM rhizomes. The highest concentrations of key pharmacological compounds, such as chlorogenic acid, ferulic acid, and ligustilide, were observed at 40℃. While relatively higher levels of total phenolics and flavonoids were also detected at 40℃ compared to other drying temperatures, the highest antioxidant activity was observed at room temperature, though it was not significantly different from that at 40℃. These findings suggest that drying COM rhizomes at 40℃ is optimal for preserving the levels of pharmacological compounds.
Abstract
The rhizome of Cnidium officinale Makino (COM) is known for its medicinal properties due to its pharmacological activity. Typically, it is thermally dried after harvesting before being processed into suitable final products. However, because thermal drying affects the levels of thermolabile compounds in COM rhizomes, suitable drying conditions are necessary to ensure the quality of the final product. In this study, we evaluated the effects of drying temperatures (30-70℃) on the levels of pharmacological and antioxidant compounds in COM rhizomes. The highest concentrations of key pharmacological compounds, such as chlorogenic acid, ferulic acid, and ligustilide, were observed at 40℃. While relatively higher levels of total phenolics and flavonoids were also detected at 40℃ compared to other drying temperatures, the highest antioxidant activity was observed at room temperature, though it was not significantly different from that at 40℃. These findings suggest that drying COM rhizomes at 40℃ is optimal for preserving the levels of pharmacological compounds.