식물자원의 항산화활성 탐색
Investigation on Antioxidant Activity in Plant Resources
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참고문헌
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초록
This study was conducted for screening on antioxidant activity of 429 plants and selecting new potential antioxidant candidates. In vitro test models such as scavenging activity on DPPH radical and inhibitory activity on linoleic acid oxidation were used in the preliminary study. Flower of Sanguisorba officinalis, flower of Sedum kamtschaticum, flower of Rumex obtusifolius, and root of Sedum kamtschaticum showed very effective antioxidant activity on DPPH radical and linoleic acid oxidation. Those plants showed 8.1, 9.4, 9.9, 11㎍/㎖ in DPPH radical scavenging activity as SC50 and did 80.4, 80.1, 84.5, 88.0% in inhibition activity on linoleic acid oxidation, respectively. Root of Sedum middendorfianum M. showed positive effects in superoxide radical scavenging activity (38.4㎍/㎖) and inhibitory effect on CuSO4-induced LDL oxidation (53.8% at final concentration of 1㎍/㎖). Gleditsia japonica Mig. showed high antioxidant activity on LDL oxidation as 71.6% at final concentration of 1㎍/㎖ and total phenol content of 958.5 ㎎% as tannic acid equivalent. In conclusion, we think that these plants having potent antioxidant activity might be studied further and could be used as new resources for many purposes including healthy food, functional cosmetics and drug development etc.
Abstract
This study was conducted for screening on antioxidant activity of 429 plants and selecting new potential antioxidant candidates. In vitro test models such as scavenging activity on DPPH radical and inhibitory activity on linoleic acid oxidation were used in the preliminary study. Flower of Sanguisorba officinalis, flower of Sedum kamtschaticum, flower of Rumex obtusifolius, and root of Sedum kamtschaticum showed very effective antioxidant activity on DPPH radical and linoleic acid oxidation. Those plants showed 8.1, 9.4, 9.9, 11㎍/㎖ in DPPH radical scavenging activity as SC50 and did 80.4, 80.1, 84.5, 88.0% in inhibition activity on linoleic acid oxidation, respectively. Root of Sedum middendorfianum M. showed positive effects in superoxide radical scavenging activity (38.4㎍/㎖) and inhibitory effect on CuSO4-induced LDL oxidation (53.8% at final concentration of 1㎍/㎖). Gleditsia japonica Mig. showed high antioxidant activity on LDL oxidation as 71.6% at final concentration of 1㎍/㎖ and total phenol content of 958.5 ㎎% as tannic acid equivalent. In conclusion, we think that these plants having potent antioxidant activity might be studied further and could be used as new resources for many purposes including healthy food, functional cosmetics and drug development etc.
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