본문 바로가기
KERD
논문

초고압 저온처리에 의한 매자나무의 면역 활성

Effect of Immune Activity on Berberis koreana Palibin by Ultra High Pressure Low Temperature Process

1

조회

0

다운로드

15

인용

0

참고문헌

키워드

초록

This study was performed to investigate a methodology of improving immune activities of Berberis koreana Palibin by ultra high pressure on low temperature extraction process. Extraction yield was enhanced up to more than 35% by above process, compare to the control and extraction average. The cytotoxicity on human kidney cell (HEK293) was showed below 20.4%, 21.6% in adding 1.0 ㎎/㎖ of the highest concentration. Generally, the extracts by ultra high pressure extraction process showed less toxicity about 5% than the other processes. It could tell that toxic materials that existing in the plant could be reduced or broken by ultra high pressure process due to can be broken bond such the hydrogen bond, the electrostatic bond, the van der Waals bond, and the hydrophobic bond, can be broken by high pressure. The result could be employed to develop a new type of functional food from B. koreana Palibin by low temperature high pressure process.

Abstract

This study was performed to investigate a methodology of improving immune activities of Berberis koreana Palibin by ultra high pressure on low temperature extraction process. Extraction yield was enhanced up to more than 35% by above process, compare to the control and extraction average. The cytotoxicity on human kidney cell (HEK293) was showed below 20.4%, 21.6% in adding 1.0 ㎎/㎖ of the highest concentration. Generally, the extracts by ultra high pressure extraction process showed less toxicity about 5% than the other processes. It could tell that toxic materials that existing in the plant could be reduced or broken by ultra high pressure process due to can be broken bond such the hydrogen bond, the electrostatic bond, the van der Waals bond, and the hydrophobic bond, can be broken by high pressure. The result could be employed to develop a new type of functional food from B. koreana Palibin by low temperature high pressure process.

참고문헌 (9)

  1. Doll R, "The causes of cancer : quantitative estimates of avoidable risks of cancer in the United States today", Journal of the National Cancer Institute, 66, pp.1191~1308 (1981)
  2. Han BH, "Effect of Ginsenosides from Panax ginseng on TNF-α production and T cell proliferation", Yakhak Hoeji, 42, pp.296~301 (1998)
  3. Hermans K, "Pressure and temperature induced phenomena in proteins. 3-8. In Winter R. (ed.) Advances in high pressure bioscience and biotechnology II" (2003), Springer-Verlag, Berlin, Germany
  4. 김철희, "초고압 추출 공정에 의한 당귀 추출물의 미백 및 자외선 차단 효과", 한국약용작물학회지, 16(4), pp.255~260 (2008), 한국약용작물학회
  5. 김철희, "초고압 공정에 의한 홍경천의 독성 감소 및 항암활성 증진", 한국약용작물학회지, 15(6), pp.411~416 (2007), 한국약용작물학회
  6. 이용규, "대식세포주 RAW264.7 세포에서 Curcumin의 Lipopolysaccharide 에 의한 Nitric Oxide 생성 억제 효과", 한국약용작물학회지, 15(6), pp.451~456 (2007), 한국약용작물학회
  7. 이현용, "초음파 병행 추출이 마황과 복분자 열수 추출물의 면역활성 증진에 미치는 효과", KSBB Journal, 19(2), pp.113~117 (2004), 한국생물공학회
  8. Yueran Z, "Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines", Biochemical and Biophysical Research Communications, 300, pp.247~252 (2003)
  9. Zhang S, "Novel high pressure extraction technology", Journal of Pharmaceutics, 278, pp.471~474 (2004)

관련 논문AI추천

이 간행물의 다른 논문 (10건)