Comparative study on the immunological functionality of HongJam produced from Baegokjam and Dodam-silkworm varieties
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To develop a robust and productive white cocoon silkworm variety suitable for HongJam production, we investigated the functionality of HongJam derived from Dodam-silkworms (DD HJ), a recently developed variety characterized by strong robustness, large body size, and easy sex differentiation. Among the extraction methods tested, hot-water extraction showed the highest yield and was therefore selected for functional evaluation. Comparative analysis revealed no significant difference in extraction efficiency between Baegokjam-HongJam hot water extract and DD-HJ-HWE. Using macrophage and natural killer cell assays, both extracts significantly enhanced immune activity by promoting immune cell proliferation and increasing phagocytic and pinocytotic functions. These findings indicate that Dodam-silkworms can serve as a promising alternative to Baegokjam for HongJam production, providing comparable immune-enhancing properties with superior rearing stability and productivity.
Abstract
To develop a robust and productive white cocoon silkworm variety suitable for HongJam production, we investigated the functionality of HongJam derived from Dodam-silkworms (DD HJ), a recently developed variety characterized by strong robustness, large body size, and easy sex differentiation. Among the extraction methods tested, hot-water extraction showed the highest yield and was therefore selected for functional evaluation. Comparative analysis revealed no significant difference in extraction efficiency between Baegokjam-HongJam hot water extract and DD-HJ-HWE. Using macrophage and natural killer cell assays, both extracts significantly enhanced immune activity by promoting immune cell proliferation and increasing phagocytic and pinocytotic functions. These findings indicate that Dodam-silkworms can serve as a promising alternative to Baegokjam for HongJam production, providing comparable immune-enhancing properties with superior rearing stability and productivity.
