Safety evaluation of Moringa oleifera Ethanol Extract as a Cosmeceutical Material
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As the quality of life has recently increased by the improvement of the standard of living, the desire for beautiful appearance has increased and it brings a huge growth of cosmetic industry. As this result, an interest of consumers about cosmetics which had proven efficacy and safety of the skin has been increased. The objective of this study was to determine the bioactive characteristics of Moringa oleifera ethanol extracts (MOEE) as a cosmeceutical material. To estimate the antioxidant activity of MOEE, the antioxidant activity of MOEE were tested with ABTS+ radical scavenging activity. And the safety of MOEE as a functional cosmetic material were confirmed and its suitability as a cosmetic material was evaluated. The antioxidant activity of MOEE, as determined by ABTS+ radical scavenging activity was confirmed to be slightly weaker than ascorbic acid used as a positive control but MOEE has a significant antioxidant activity. MOEE was judged to be a non-irritant substance in the evaluation of skin irritation using Labcyte EPI-MODEL24 and in the evaluation of ocular mucous membrane irritation using BCOP assay. In conclusion, MOEE has antioxidant activity and it is safe in any circumstance. It is considered that this study provided a practicability of basic data as a functional cosmetic material of MOEE.
Abstract
As the quality of life has recently increased by the improvement of the standard of living, the desire for beautiful appearance has increased and it brings a huge growth of cosmetic industry. As this result, an interest of consumers about cosmetics which had proven efficacy and safety of the skin has been increased. The objective of this study was to determine the bioactive characteristics of Moringa oleifera ethanol extracts (MOEE) as a cosmeceutical material. To estimate the antioxidant activity of MOEE, the antioxidant activity of MOEE were tested with ABTS+ radical scavenging activity. And the safety of MOEE as a functional cosmetic material were confirmed and its suitability as a cosmetic material was evaluated. The antioxidant activity of MOEE, as determined by ABTS+ radical scavenging activity was confirmed to be slightly weaker than ascorbic acid used as a positive control but MOEE has a significant antioxidant activity. MOEE was judged to be a non-irritant substance in the evaluation of skin irritation using Labcyte EPI-MODEL24 and in the evaluation of ocular mucous membrane irritation using BCOP assay. In conclusion, MOEE has antioxidant activity and it is safe in any circumstance. It is considered that this study provided a practicability of basic data as a functional cosmetic material of MOEE.
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