Bacterial Reverse Mutation (Ames) Test with Potassium Nitrate and 2-Methylpentane
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We investigated the genotoxicities or mutagenicities of two chemicals (potassium nitrate and 2-methylpentane)that have limited toxicological data in spite of their common usage based on Ames reverse mutation test. In this test, treatment of two chemicals at each five dose did not induce mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA 1537, and in Escherichia coli WP2uvrA with and without metabolic activation. These results indicate that two chemicals do not have mutagenic potentials under the conditions of our study
Abstract
We investigated the genotoxicities or mutagenicities of two chemicals (potassium nitrate and 2-methylpentane)that have limited toxicological data in spite of their common usage based on Ames reverse mutation test. In this test, treatment of two chemicals at each five dose did not induce mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA 1537, and in Escherichia coli WP2uvrA with and without metabolic activation. These results indicate that two chemicals do not have mutagenic potentials under the conditions of our study
참고문헌 (21)
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