음주량이 혈중 중성지방 농도에 미치는 영향에 있어서 흡연량과 신체질량지수의 매개 역할: 국민건강영양조사 7기 자료
The Mediating Role of Smoking and Body Mass Index on the Relationship between Alcohol Consumption and Blood Triglyceride Levels among Korean Adults: The 7th Korean National Health and Nutrition Examination Survey
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연구배경: 음주량이 혈중 중성지방 농도에 미치는 직접 효과에 대한 국내 연구들은 많이 있지만 음주량이 다른 매개변수를 경유하여 혈중 중성지방 농도에 미치는 간접 효과에대한 연구는 부족하다. 따라서 본 연구에서는 연속형 변수를 이용하여 음주량이 혈중 중성지방 농도에 미치는 직접적인 영향을 분석하고 흡연량과 신체질량지수를 매개변수로하는 간접 효과를 알아보고자 하였다. 방법: 제7기 국민건강영양조사 중 3차년도(2018년) 자료를 이용하였으며 조사에 참여한 20세 이상 성인 5,867명을연구 대상으로 선정하였다. 음주량이 혈중 중성지방 농도에미치는 직접적인 영향 및 흡연량, 신체질량지수를 통한 간접 효과를 분석하기 위해 다중회귀분석과 SPSS PROCESS macro를 이용한 매개분석을 실시하였다. 결과: 음주량, 흡연량, 신체질량지수는 혈중 중성지방 농도에 양(+)의 유의적인(P<0.01) 영향을 미치는 것으로 나타났다. 이러한 결과는 음주량의 증가, 흡연량의 증가, 신체질량지수의 증가는 혈중 중성지방 농도를 증가시킨다는 것을나타낸다. 또한 음주량은 흡연량과 신체질량지수를 통하여혈중 중성지방 농도에 유의한 영향을 미치는 간접 효과가나타났다. 결론: 본 연구에서 음주량은 혈중 중성지방 농도의 증가에 직접적인 영향을 미치고 흡연량과 신체질량지수를 통해혈중 중성지방 농도의 증가에 간접적으로도 영향을 미친다는 것을 확인하였다. 혈중 중성지방 농도를 낮추기 위해 음주량, 흡연량, 신체질량지수를 관리하여야 할 뿐만 아니라음주가 흡연량 증가 및 신체질량지수 증가로 연결되지 않도록 하는 노력이 필요할 것으로 보인다.
Abstract
Background: Although there are many studies of association between alcohol consumption and hypertriglyceridemia with categorized variables, it is insufficient to study association between quantity of alcohol consumption and triglyceride levels as continuous variables. Therefore, this study investigates direct effect of alcohol consumption on triglyceride levels. Additionally, this study examines indirect effects through smoking and body mass index (BMI). Methods: This study uses data from the 7th Korean National Health and Nutrition Examination Survey. Among the participants, 5,867 adults ≥20 years of age are enrolled. To test the association between quantity of alcohol consumption and triglyceride levels and indirect effects through smoking and BMI, this study conducts multi-regression analysis by SPSS PROCESS macro. Results: The results are as follows. First, alcohol consumption has positive(+) effects on smoking, BMI, and triglyceride levels significantly. Second, smoking and BMI have a positive(+) effect on triglyceride levels significantly. Third, alcohol consumption has positive(+) effects on triglyceride levels through smoking and BMI indirectly. Conclusions: Alcohol consumption has a direct effect on triglyceride levels, also has indirect effects through smoking and BMI positively
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