전안부 빛간섭단층촬영기와 이중샤임플러그 전안부사진기로 측정한 전안부 계측치의 비교
Comparison of Anterior Segment Parameters Obtained by Anterior Segment Optical Coherence Tomography and Dual Rotating Scheimpflug Camera
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목적: Galilei® dual-Scheimpflug analyzer와 Anterior segment optical coherence tomography (Cirrus OCT®)로 측정한 전안부 계측치의 비교 및 반복성에 대해서 알아보고자 하였다. 대상과 방법: 정상인 24명의 48안을 대상으로 Galilei®와 Cirrus OCT®로 중심각막두께, 최소각막두께, 앞방깊이, 전방각을 동일한 검사자가 2회 측정하여 검사자 내 반복성을 평가하고 두 기계 간의 측정값을 비교하였다. 결과: 두 검사기구로 측정한 중심각막두께, 앞방깊이, 전방각은 모두 높은 반복성을 보였으며(급내상관계수≥0.90) 최소각막두께의 반복성은 다소 낮았다(급내상관계수≥0.69). Galilei®로 측정한 중심각막두께는 Cirrus OCT®로 측정한 값보다 평균 0.26 ± 7.11 μm 만큼 얇았고, 최소 각막두께는 평균 0.37 ± 7.35 μm 더 두껍게 측정하였으나 통계적 유의성은 없었다. 앞방깊이는 Cirrus OCT®로 측정한 값보다 평균 0.22 ± 0.08 mm 깊었고(p<0.007), 전방각은 7.87°± 1.32°더 큰 소견을 보였다(p=0.04). 두 검사기구의 중심각막두께, 앞방깊이, 전방각의 95% 일치도 범위는 각각 85.30 μm, 1.43 mm, 27.90°였으며 최소각막두께의 일치도의 범위는 다소 컸다(109.58 μm). 결론: 정상안에서 서로 다른 원리의 전안부 계측장비로 측정한 결과가 비교적 상응하는 결과를 보였고 두 장비 모두 재현성이 우수함을 알 수 있으나 계측치의 일치도 범위가 다소 커 장비 간 수치의 상호교환은 어려움을 확인하였다.
Abstract
Purpose: To compare the anterior segment measurements with a Galilei® dual Scheimpflug analyzer and anterior segment optical coherence tomography (Cirrus OCT®). Methods: Forty-eight eyes of 24 normal young adults were assessed for repeatability with two identical measurements of the central corneal thickness, minimum corneal thickness, anterior chamber depth, and anterior chamber angle using the Galilei® dual- Scheimpflug analyzer and Cirrus OCT®. Results: The central corneal thickness, anterior chamber depth, and anterior chamber angle were highly reproducible and repeatable (intraclass correlation coefficient ≥ 0.90). Repeatability of the minimum corneal thickness was slightly lower (intraclass correlation coefficient ≥ 0.69). The mean corneal thickness measured using the Galilei® dual Scheimpflug analyzer was 0.26 ± 7.11 μm thinner than that measured using the Cirrus OCT®, and the mean corneal thickness was 0.37 ± 7.35 μm thicker, but was not statistically significant. The anterior chamber depth was 0.22 ± 0.08 mm deeper than the Cirrus OCT® (p < 0.007), and the anterior chamber angle was 7.87° ± 1.32° larger than the Cirrus OCT® (p = 0.04). The 95% agreements of the central corneal thickness, anterior chamber depth, and anterior chamber angle between instruments were 85.30 μm, 1.43 mm, and 27.90°, respectively, and showed a high correlation (r ≥ 0.90; p < 0.001). The repeatability of the minimum corneal thickness was slightly low (r = 0.69; p <0.001), and the range of agreement was larger (109.58 μm). Conclusions: The anterior segment measurements obtained with the dual rotating Scheimpflug camera and new anterior segment OCT in normal eyes was comparable and reproducible. However, the agreement ranges of the measured values were relatively large, so it was difficult to exchange values between instruments.
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