갈릴레이와 세극등 빛간섭단층촬영기로 측정한 전안부계측치의 반복성 및 비교
Comparison and Repeatability of Anterior Segment Parameters Obtained by Galilei and Slit-lamp Optical Coherence Tomography
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목적: Galilei dual-Scheimpflug analyzer와 slit-lamp optical coherence tomography (SL-OCT)로 측정한 전방깊이와 중심각막두께 의 반복성과 차이에 대해서 알아보고자 하였다. 대상과 방법: 젊은 정상인 68명의 68안을 대상으로 Galilei와 SL-OCT로 전방깊이와 중심각막두께를 동일한 검사자가 3회 측정하여 검사자내 반복성을 평가하고 두 기계간의 측정값을 비교하였다. 결과: 두 검사기구로 측정한 전방깊이와 중심각막두께는 모두 높은 반복성을 보였으며(급내상관계수≥0.994), Galilei로 측정한 전방깊 이는 SL-OCT로 측정한 값보다 평균 0.11 ± 0.09 mm, 중심각막두께는 평균 14.01 ± 7.38 μm 더 높은 소견을 보였다(p＜0.001). 두 검사기구의 전방깊이와 중심각막두께의 95% 일치도 범위는 각각 0.36 mm, 27.66 μm이었으며 높은 상관관계를 보였다(상관계수≥ 0.89, p＜0.001). 결론: Galilei와 SL-OCT를 이용하여 측정한 전방깊이와 중심각막두께는 높은 검사자내 반복성을 보였으나 두 검사기계 사이에 유의한 차이를 보여 결과 해석 시 이에 대한 고려가 필요할 것으로 생각한다.
Abstract
Purpose: To evaluate the repeatability and comparability of anterior chamber depth (ACD) and central corneal thickness (CCT) measurements obtained by Galilei dual Scheimpflug analyzer (Ziemer, Port, Switzerland) and slit-lamp optical coherence tomography (SL-OCT; Heidelberg Engineering, Dossenheim, Germany). Methods: ACD and CCT were measured by Galilei and SL-OCT in 68 eyes of 68 healthy young subjects. Each measurement was performed 3 times by a single examiner, and the repeatability of 3 consecutive measurements was analyzed. ACD and CCT measurements were compared between the 2 devices. Results: Both Galilei and SL-OCT showed high repeatability (ICCs ≥ 0.994) for ACD and CCT measurements. The mean ACD and CCT measured by Galilei were greater than SL-OCT measurements by 0.11 ± 0.09 mm and 14.01 ± 7.38 μm, respectively. The 95% limit of agreement values for ACD and CCT measurements were 0.36 mm, 27.66 μm, respectively, and were highly correlated (correlation coefficients ≥ 0.89, p < 0.001). Conclusions: Although the repeatability of each device was high, ACD and CCT obtained by Galilei and SL-OCT were significantly different. These differences should be considered when interpreting ACD and CCT measurements obtained by the 2 devices.
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