파장가변 빛간섭단층촬영계와 샤임플러그 부분결합간섭계의 전안부 계측치 비교
Comparison of Anterior Segment Measurements Between Swept-source Optical Coherence Tomography and Schiempflug Coherence Interferometer
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목적: 파장가변 빛간섭단층촬영계(Anterion®, Heidelberg Engineering Inc., Heidelberg, Germany)와 샤임플러그 부분결합간섭계(Pentacam HR®, OCULUS, Wetzlar, Germany)의 전안부 계측치를 비교하고 측정값 간 일치도를 평가하고자 하였다. 대상과 방법: 총 43명, 65안에 대하여 파장가변 빛간섭단층촬영계와 샤임플러그 부분결합간섭계로 측정한 각막 전면 및 후면 곡률값, 카티지언 난시 및 경사난시, 전방깊이, 중심각막두께를 비교하고 측정값 간 일치도를 분석하였다. 결과: Anterion®과 Pentacam HR®으로 측정한 전안부 계측치의 기기 간 평균 차이는 각막 전면의 편평 각막곡률, 가파른 각막곡률및 평균 각막곡률은 -0.13 ± 0.34, -0.02 ± 0.33, -0.05 ± 0.31, 각막 전면 J0 및 J45는 -0.03 ± 0.39, -0.06 ± 0.35, 각막후면의 편평 각막곡률, 가파른 각막곡률 및 평균 각막곡률은 0.12 ± 0.09, 0.07 ± 0.08, 0.10 ± 0.06, 각막 후면 J0 및 J45는 -0.02 ± 0.14, 0.01 ± 0.16, 전방깊이 및 중심각막두께는 0.04 ± 0.06, -3.51 ± 7.42로 확인되었다. 각막 후면 난시 제외한 계측치에서급내상관계수는 0.75 이상이었다. 결론: Anterion®과 Pentacam HR®으로 측정한 전안부 계측치 간 평균 차이 및 95% 일치도 한계는 선행 연구와 비슷한 정도로 확인되며 비교적 높은 일치도를 보였으나, 통계적으로 유의한 차이를 보인 지표들이 있으며 일치도 범위를 고려하였을 때 인공수정체 도수계산 시 오차 가능성이 있어 측정값을 상호 교환적으로 사용하기는 어렵다.
Abstract
Purpose: To assess the agreement between anterior segment measurements obtained using swept-source optical coherence tomography (Anterion®, Heidelberg Engineering Inc., Heidelberg, Germany) and Scheimpflug partial coherence interferometry (Pentacam HR®, OCULUS, Wetzlar, Germany). Methods: We analyzed the anterior and posterior corneal keratometry, Cartesian astigmatism (J0), oblique astigmatism (J45), anterior chamber depth (ACD), and central corneal thickness (CCT) measurements obtained using the two devices in 65 eyes of 43 subjects. Results: The mean differences between the anterior flat K, anterior steep K, anterior mean K, anterior J0, anterior J45, posterior flat K, posterior steep K, posterior mean K, posterior J0, posterior J45, ACD, and CCT measurements were -0.13 ± 0.34, -0.02 ± 0.33, -0.05 ± 0.31, -0.03 ± 0.39, -0.06 ± 0.35, 0.12 ± 0.09, 0.07 ± 0.08, 0.10 ± 0.06, -0.02 ± 0.14, 0.01 ± 0.16, 0.04 ± 0.06, and -3.51 ± 7.42, respectively. All measurements except posterior J0 and J45 had interclass correlation coefficients greater than 0.75. Conclusions: The mean differences and 95% limits of agreement in this study are consistent with previously reported values. There was a high level of agreement between Anterion® and Pentacam HR®. However, considering the statistically significant differences and limits of agreement for certain measurements, caution should be exercised when assuming interchangeability between these devices.
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