Atypical bone change of spine caused by epidural venous thrombosis in systemic lupus erythematosus with antiphospholipid syndrome

Abstract

The exact pathophysiological relationship between epidural venous thrombosis and fatty deposition in the vertebral body is not clear. But we suggest that the prolonged gradual disturbance of the microvascular circulation due to partial epidural venous thrombosis caused by the antiphospholipid antibody, together with the long-term use of steroid, may have led to fatty deposition in the vertebral body rather than the typical avascular necrosis caused by sudden vascular insufficiency.