본문 바로가기
KERD
논문KCI 등재

Effects of Hand Training During the Aftereffect Period of Low-Frequency rTMS in Subacute Stroke Patients

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류재활의학

초록

Objective To investigate the effects of hand training using low-frequency repetitive transcranial magnetic stimulation (rTMS) within the aftereffect period on hand function in patients with subacute stroke. Methods The subacute stroke patients with hand weaknesses were divided randomly into two groups. Patients in the intervention group underwent hand training within the aftereffect period, that is, immediately after receiving low-frequency rTMS treatment. Patients in the control group underwent hand training 2 hours after the low-frequency rTMS treatment. A manual function test (MFT) for ‘grasp and pinch’ and ‘hand activities’; a manual muscle test (MMT) for ‘grasp’, ‘release’, and ‘abductor pollicis brevis (APB)’; and the Modified Ashworth Scale for finger flexion were performed and measured before and immediately after combined therapy as well as 2 weeks after combined therapy. Conclusion Hand training immediately after low-frequency rTMS showed more rapid improvement in the motor power of hands than hand training conducted 2 hours after low-frequency rTMS. Our results suggest that conducting hand training immediately after low-frequency rTMS could be an improved useful therapeutic option in subacute stroke patients.

Abstract

Objective To investigate the effects of hand training using low-frequency repetitive transcranial magnetic stimulation (rTMS) within the aftereffect period on hand function in patients with subacute stroke. Methods The subacute stroke patients with hand weaknesses were divided randomly into two groups. Patients in the intervention group underwent hand training within the aftereffect period, that is, immediately after receiving low-frequency rTMS treatment. Patients in the control group underwent hand training 2 hours after the low-frequency rTMS treatment. A manual function test (MFT) for ‘grasp and pinch’ and ‘hand activities’; a manual muscle test (MMT) for ‘grasp’, ‘release’, and ‘abductor pollicis brevis (APB)’; and the Modified Ashworth Scale for finger flexion were performed and measured before and immediately after combined therapy as well as 2 weeks after combined therapy. Conclusion Hand training immediately after low-frequency rTMS showed more rapid improvement in the motor power of hands than hand training conducted 2 hours after low-frequency rTMS. Our results suggest that conducting hand training immediately after low-frequency rTMS could be an improved useful therapeutic option in subacute stroke patients.

참고문헌 (32)

  1. Chen R, "Nervous system reorganization following injury", Neuroscience, 111, pp.761~773 (2002)[DOI]
  2. Pascual-Leone A, "The plastic human brain cortex", Annu Rev Neurosci, 28, pp.377~401 (2005)[DOI]
  3. Hummel FC, "Drivers of brain plasticity", Curr Opin Neurol, 18, pp.667~674 (2005)[DOI]
  4. Rijntjes M, "Mechanisms of recovery in stroke patients with hemiparesis or aphasia: new insights, old questions and the meaning of therapies", Curr Opin Neurol, 19, pp.76~83 (2006)[DOI]
  5. Ward NS, "Mechanisms underlying recovery of motor function after stroke", Arch Neurol, 61, pp.1844~1848 (2004)
  6. Barker AT, "Non-invasive magnetic stimulation of human motor cortex", Lancet, 1, pp.1106~1107 (1985)
  7. Amassian VE, "Focal stimulation of human cerebral cortex with the magnetic coil: a comparison with electrical stimulation", Electroencephalogr Clin Neurophysiol, 74, pp.401~416 (1989)[DOI]
  8. Pascual-Leone A, "Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex", Brain, 117, pp.847~858 (1994)[DOI]
  9. Sebastianelli L, "Low-frequency rTMS of the unaffected hemisphere in stroke patients: a systematic review", Acta Neurol Scand, 136, pp.585~605 (2017)[DOI]
  10. Takeuchi N, "Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke", Stroke, 36, pp.2681~2686 (2005)[DOI]
  11. Fregni F, "A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the unaffected hemisphere in stroke patients", Stroke, 37, pp.2115~2122 (2006)[DOI]
  12. Lefaucheur JP, "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)", Clin Neurophysiol, 125, pp.2150~2206 (2014)[DOI]
  13. Khedr EM, "Therapeutic role of rTMS on recovery of dysphagia in patients with lateral medullary syndrome and brainstem infarction", J Neurol Neurosurg Psychiatry, 81, pp.495~499 (2010)[DOI]
  14. Mansur CG, "A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients", Neurology, 64, pp.1802~1804 (2005)[DOI]
  15. Thut G, "A review of combined TMSEEG studies to characterize lasting effects of repetitive TMS and assess their usefulness in cognitive and clinical neuroscience", Brain Topogr, 22, pp.219~232 (2010)[DOI]
  16. Motamed Vaziri P, "Low frequency repetitive transcranial magnetic stimulation to improve motor function and grip force of upper limbs of patients with hemiplegia", Iran Red Crescent Med J, 16, pp.e13579~ (2014)
  17. Avenanti A, "Low-frequency rTMS promotes use-dependent motor plasticity in chronic stroke: a randomized trial", Neurology, 78, pp.256~264 (2012)[DOI]
  18. Conforto AB, "Transcranial magnetic stimulation in mild to severe hemiparesis early after stroke: a proof of principle and novel approach to improve motor function", J Neurol, 259, pp.1399~1405 (2012)[DOI]
  19. Kakuda W, "A multi-center study on low-frequency rTMS combined with intensive occupational therapy for upper limb hemiparesis in post-stroke patients", J Neuroeng Rehabil, 9, pp.4~ (2012)[DOI]
  20. Leesuk Kim, "Effect of Repetitive Transcranial Magnetic Stimulation on Patients with Brain Injury and Dysphagia", Annals of Rehabilitation Medicine, 35(6), pp.765~771 (2011), 대한재활의학회
  21. Miyamoto S, "Reliability and validity of the Manual Function Test in patients with stroke", Am J Phys Med Rehabil, 88, pp.247~255 (2009)[DOI]
  22. Sloan RL, "Inter-rater reliability of the modified Ashworth Scale for spasticity in hemiplegic patients", Int J Rehabil Res, 15, pp.158~161 (1992)[DOI]
  23. Hosomi K, "Daily repetitive transcranial magnetic stimulation for poststroke upper limb paresis in the subacute period", J Stroke Cerebrovasc Dis, 25, pp.1655~1664 (2016)[DOI]
  24. Baumer T, "Repeated premotor rTMS leads to cumulative plastic changes of motor cortex excitability in humans", Neuroimage, 20, pp.550~560 (2003)[DOI]
  25. Grefkes C, "Modulating cortical connectivity in stroke patients by rTMS assessed with fMRI and dynamic causal modeling", Neuroimage, 50, pp.233~242 (2010)[DOI]
  26. Cramer SC, "Repairing the human brain after stroke. I. Mechanisms of spontaneous recovery", Ann Neurol, 63, pp.272~287 (2008)[DOI]
  27. Johansson BB, "Brain plasticity and stroke rehabilitation: the Willis lecture", Stroke, 31, pp.223~230 (2000)[DOI]
  28. Indredavik B, "Treatment in a combined acute and rehabilitation stroke unit: which aspects are most important?", Stroke, 30, pp.917~923 (1999)[DOI]
  29. Dafotakis M, "The effects of 1 Hz rTMS over the hand area of M1 on movement kinematics of the ipsilateral hand", J Neural Transm (Vienna), 115, pp.1269~1274 (2008)[DOI]
  30. Nowak DA, "Effects of low-frequency repetitive transcranial magnetic stimulation of the contralesional primary motor cortex on movement kinematics and neural activity in subcortical stroke", Arch Neurol, 65, pp.741~747 (2008)
  31. Khedr EM, "Long-term effect of repetitive transcranial magnetic stimulation on motor function recovery after acute ischemic stroke", Acta Neurol Scand, 121, pp.30~37 (2010)[DOI]
  32. Malcolm MP, "Repetitive transcranial magnetic stimulation as an adjunct to constraint-induced therapy: an exploratory randomized controlled trial", Am J Phys Med Rehabil, 86, pp.707~715 (2007)[DOI]

관련 논문AI추천

Comparison of the Effects of 1 Hz and 20 Hz rTMS on Motor Recovery in Subacute Stroke Patients김철, 이병주, 최희은, Hee Jin Jung, Ki Hoon Lee, Young-Joon Lim대한재활의학회 · Annals of Rehabilitation Medicine2014 · 제38권 제5호The Persisted Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation to Augment Task-Specific Induced Hand Recovery Following Subacute Stroke: Extended StudyChutima Jalayondeja, Jarugool Tretriluxana, Jenjira Thanakamchokchai, Narawut Pakaprot, Suradej Tretriluxana대한재활의학회 · Annals of Rehabilitation Medicine2018 · 제42권 제6호Effect of Repetitive Transcranial Magnetic Stimulation in Post-stroke Patients with Severe Upper-Limb Motor Impairment김덕용, 김주선, 정강재, 홍준택, Hyunjung Kim, Kim Dae Hyun대한뇌신경재활학회 · 뇌신경재활2020 · 제13권 제1호Factors Associated With Upper Extremity Functional Recovery Following Low-Frequency Repetitive Transcranial Magnetic Stimulation in Stroke Patients김서영, 김태욱, 신성봉, 이성재, 현정근대한재활의학회 · Annals of Rehabilitation Medicine2016 · 제40권 제3호Factors Associated With Upper Extremity Motor Recovery After Repetitive Transcranial Magnetic Stimulation in Stroke Patients김민아, 김상범, 이경우, 이숙정, 이종화, 최수진대한재활의학회 · Annals of Rehabilitation Medicine2015 · 제39권 제2호반복 경두개 자기자극 후 상지운동이 편마비 상지 기능 회복에 미치는 영향강성진, 류병주, 박시운, 이지연, 최경인, 최은석대한근전도전기진단의학회 · 대한근전도 전기진단의학회지2010 · 제12권 제1호

이 간행물의 다른 논문 (20건)