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Antifungal Activity of Bioactive Fractions on the Dermatophytic Fungus

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Cytotoxic and antifungal activities were strongly shown by Fr. 4 (218 mg, P388 IC50 652 ng/mL at 75 μg/disc, IC50 834 ng/mL at 30 μg/disc and HM 8). The subfraction 4 - 3 that showed the most activity was cytotoxic to murine leukaemia cells ATCC CCL 46 P388D1, (44.0 mg, P388 IC50 302 ng/mL at 30 μg/disc).

Abstract

Cytotoxic and antifungal activities were strongly shown by Fr. 4 (218 mg, P388 IC50 652 ng/mL at 75 μg/disc, IC50 834 ng/mL at 30 μg/disc and HM 8). The subfraction 4 - 3 that showed the most activity was cytotoxic to murine leukaemia cells ATCC CCL 46 P388D1, (44.0 mg, P388 IC50 302 ng/mL at 30 μg/disc).

참고문헌 (8)

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  4. "Screening for biological activity of crude extract and fractions from Brachyglottis monroi", 17(3), pp.826~828 (2003)
  5. "Antitumor evaluation of cannabidiol and its derivatives by colorimetric methods", 16, pp.101~107 (2000)
  6. "Isolation of cytotoxic component from Trichocolea hatcheri Orien", 1, pp.49~56 (2001)
  7. "Geranyl phenyl ethers from the New Zealand liverwort Trichocolea hatcheri", 61, pp.126~129 (1998)
  8. "A method for the rapid partitioning of natural product extracts", pp.290~292 (1987)

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