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Study on Anti-allergic Effects of Electroacupuncture in Allergic Mouse Model

Ji Won Yoon|Kyoung Ah Jeong|Zang Hee Cho|Kang Keyng Sung
한의병리학회 (The Society of Pathology in Korean Medicine)|2006.02|동의생리병리학회지 (Journal of Physiology & Pathology in Korean Medicine)|제20권 제1호|pp. 196-201

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주제분류한의학

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Abstract

Electroacupuncture(EA) is commonly used in various diseases. In the present study, the effect of EA in the allergic mouse model was examined. Allergy is generated via immunological mechanism and non-immunological mechanism. Mast cells activated by those mechanisms get to release various substances such as histamine, leukotrienes, prostaglandin, TNF-α, IL-4, IL-6, etc. which induce allergic reactions and the following inflammatory responses. To evaluate the anti-allergic effects of EA, mortality, ear swelling response, vascular permeability and cytokine secretion were investigated in EA group and non-EA group of which mice were compound 48/80-induced allergy model or PCA model. Compound 48/80 induces allergic reaction via non-immunological mechanism and PCA model is generated through the same mechanism with immediate-type(Type1) allergic reaction, one of immunological allergic reactions. EA inhibited compound 48/80-induced ear swelling response but did not inhibit the systemic anaphylaxis. EA also inhibited passive cutaneous anaphylaxis(PCA) activated by anti-dinitrophenol IgE. In addition, EA inhibited IL-6 and TNF-α secretion from 48 h PCA in mice. These results indicate that EA may be used for the treatment of mast cell-mediated allergic diseases, especially immediate-type(Type 1) allergy and non-immunologically mediated allergy.

참고문헌 (40)

  1. "The effect of acupuncture on β-endorphin ACTH and Cortisol level in serum of chronic LBP patient The Journal of Korean Acupuncture & Moxibustion 20", pp.117~1303 (2003)
  2. "The inflammatory reflex", pp.853~859
  3. "Neural Substrates and Functional Hypothesis of Acupuncture Mechanisms", pp.172~186 (2003)
  4. "Review of complementary and alternative medicine in treatment of ocular allergies", pp.395~399 (2003)
  5. "Study on cytokines IL-2 IL-10 in patients of chronic allergic rhinitis treated with acupuncture", pp.104~6 111 (2002)
  6. "Suppressive effect of acupuncture on delayed-type hypersensitivity to trinitrochlorobenzene and involvement of opiate receptors International Journal of Immunopharmacology 14", pp.661~665 (1992)
  7. "Non-opioid-dependent anti-inflammatory effects of low frequency electroacupuncture", pp.327~334 (2004)
  8. "Involvement of central opioidergic and nonopiodergic neuroendocrine systems in the suppressive effect of acupuncture on delayed type allergy in mice International Journal of Immunopharmachology 15", pp.501~508 (1993)
  9. "A new method for extraction of extravasated dye in the skin and the influence of fasting stress on passive cutaneous allergy in guinea pigs and rats", shio(ya), pp.89~101 (1978)
  10. "Raised serum levels of tumor necrosis factor in parasitic infections", pp.~2 1365 (1986)
  11. "Prevention and correction of stress-induced immunodeficiency by atrial electroacupuncture", pp.21~24 (1989)
  12. "Acupuncture for immune-mediated disorders", pp.162~193 (1992)
  13. "Effect of acupuncture on interleukin-2 level and NK cell immunoactivity of peripheral blood of malignant tumor patients", pp.537~539 (1994)
  14. "Role of TGF-β1 on the IgE-dependent anaphylaxis reaction Journal of Immunology 162", pp.4960~4965 (1994)
  15. "Functional compartments in rat mast cells for cAMP and calcium on histamin release", pp.343~350 (2000)
  16. "Antiallergy drugs from Oriental medicines", 1, pp.1~7 (2000)
  17. "Ocular anaphylaxis induced in the rat bytopical application of compound 48", 80, 1989, 192 145~153
  18. "Suppression of L-histidine decarboxylase mRNA expression by methyleugenol" (1989)
  19. "Lavender oil inhibits immediate-type allergic reaction in mice and rats", pp.221~226 (1999)
  20. "flos inhibits mast celldependent immediate-type allergic reactions.", pp.107~111 (1999)
  21. "Mast cells in the murine oral mucosa are of the connective tissue-type", regional immu(logy 3), pp.35~41 (1990)
  22. "cells to acquire responsiveness to compound 48", 80 Journal of Immunology 150, 1993, 617~624
  23. "Direct activation of GTP-binding regulatory proteins", pp.260~262 (1990)
  24. "Interaction of substance P compound 48", 80 and mastoparan with α-subunit C-terminal of G protein, 1990, 355~358
  25. "The receptor with high affinity for immunoglobulin E Annual Review of Immunology 4", pp.419~470 (1986)
  26. "Structure-function relationships in the mast cell high affinity receptor for IgE Role of the cytoplasmic domains and of the beta subunit Journal of Biological Chemistry 266", pp.22613~22620 (1991)
  27. "Tongkyutang inhibits mast cell-dependent allergic reactions and inflammatory cytokine secretion", pp.35~41 (2002), Clinica Chimica Acta 319
  28. "Suppression of immunoglobulin E-mediated anaphylactic reaction by Alpinia oxyphylla in rats Immunopharmacology and Immunotoxicology 22", pp.267~277 (2000)
  29. "Autocrine regulation of cord blood-derived human mast cell activation by IL-10", pp.80~86 (2001)
  30. "IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide NF-kappa B is decisively involved in the expression of IL-9 Journal of Immunology 166", pp.4391~4398 (2001)
  31. "Inhibition of IgE-induced activation of human mast cells by IL-10", pp.694~704 (2001)
  32. "Pulmonary expression of interleukin-13 causes inflammation Journal of Clinical Investigation 103", pp.779~788 (1999)
  33. "Theoharides", di gioacchi, pp.331~335 (2002)
  34. "IL-6 enhances IgE-dependent histaminrelease from human peripheral blood-derived cultured mast cells", pp.~20 (2002)
  35. "TNF-alpha contributes to the development of allergic rhinitis in mice", pp.134~140 (2003)
  36. "Mast cell-derived TNF-alpha primes sensory nerve endings in a pulmonary hypersensitivity reaction", pp.5297~5302 (2002)
  37. "Interleukin 6 plays a key role in the development of antigen-induced arthritis Proceedings of The National Academy of Sciences of The United States of America 95", pp.~8222 (1998)
  38. "IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis roles of IL-6 in the activation and differentiation of autoreactive T cells Journal of Immunology 161" (1998)
  39. "Secretion of TNF-a from a rat mast cell line is a brefeldin A-sensitive and a calcium", protein kinase C-regulated process Journal of Immunology 153, 1994, 2609~2617
  40. "Secretion of TNF-a from a rat mast cell line is a brefeldin A-sensitive and a calcium", protein kinase C-regulated process Journal of Immunology 153, 1994, 2609~2617

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