복강 내 다발성 림프절 전이를 동반한 원발성 식도 소세포암 1예
A Case of Primary Esophageal Small Cell Carcinoma with Intraperitoneal Multiple Lymph Node Metastasis
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초록
원발성 식도 소세포암은 1952년에 처음으로 보고한 이후 세계적으로 300예 미만이 보고된 드문 질환으로 국내에는 19예가 보고되었다. 식도 소세포암은 폐에 발생한 소세포암과 마찬가지로 병의 진행속도가 빠르고 조기에 전이를 잘하는 것으로 알려져 있으나, 전이방식이나 치료법은 뚜렷이 정립되어 있지 않다. 저자 등은 연하곤란과 심와부 통증으로 내원한 58세 남자에서 복강 내에 다발성 림프절 전이를 동반한 원발성 식도 소세포암을 진단하고, irinotecan과 cisplatin으로 항암화학요법 시행한 후 종양의 크기가 감소하였고, 증상이 호전된 예를 경험하였기에 국내외의 문헌고찰과 함께 보고한다.
Abstract
Two cases of esophageal small cell carcinoma were reported on for the first time in 1952. There have been only a few published series on the patients with esophageal small cell carcinoma, and only 19 cases have been reported in Korea. As in the case of small cell carcinoma of the lung, the esophageal small cell carcinoma is known to show rapid progression and early metastasis. Yet much remains to be uncovered about the clinical features, optimal treatment and natural history of this disease. We report here on a case of primary esophageal small cell carcinoma with intraperitoneal multiple lymph node metastasis. The size of the tumor was markedly decreased by combination chemotherapy.
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