본문 바로가기
KERD
논문KCI 등재

결핵성 흉막염의 진단과 치료

Diagnosis and Treatment of Tuberculous Pleuritis

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류내과학

초록

Tuberculous (TB) pleuritis is the second most common form of extrapulmonary tuberculosis. Because the yield of pleural fluid mycobacterial culture is as low as 20% and the pleural biopsy is rather invasive, the measurement of adenosine deaminase (ADA) has been a cornerstone of the diagnosis of TB pleuritis. If the ADA level of pleural fluid is higher than 70 IU/L, the diagnosis of TB pleuritis can be made safely. The treatment is based on a standard short course anti-TB treatment starting with isoniazid, rifampicin, ethambutol, and pyrazinamide. Although systemic steroids and drainage of pleural fluid have been tried to reduce the residual pleural thickening, the results are contradicting. (Korean J Med 2011;81:150-153)

Abstract

Tuberculous (TB) pleuritis is the second most common form of extrapulmonary tuberculosis. Because the yield of pleural fluid mycobacterial culture is as low as 20% and the pleural biopsy is rather invasive, the measurement of adenosine deaminase (ADA) has been a cornerstone of the diagnosis of TB pleuritis. If the ADA level of pleural fluid is higher than 70 IU/L, the diagnosis of TB pleuritis can be made safely. The treatment is based on a standard short course anti-TB treatment starting with isoniazid, rifampicin, ethambutol, and pyrazinamide. Although systemic steroids and drainage of pleural fluid have been tried to reduce the residual pleural thickening, the results are contradicting. (Korean J Med 2011;81:150-153)

참고문헌 (29)

  1. Global tuberculosis control: a short update to the 2009 report, "World Health Organization", World Health Organization, ~ (2009)
  2. Rieder HL, "Extrapulmonary tuberculosis in the United States", Am Rev Respir Dis, 141, pp.347~351 (1990)
  3. Cowie RL, "Extra-pulmonary tuberculosis: a high frequency in the absence of HIV infection", Int J Tuberc Lung Dis, 1, pp.159~162 (1997)
  4. Elder NC, "Extrapulmonary tuberculosis. A review", Arch Fam Med, 1, pp.91~98 (1992)
  5. Valdés L, "The etiology of pleural effusions in an area with high incidence of tuberculosis", Chest, 109, pp.158~162 (1996)
  6. Berger HW, "Tuberculous pleurisy", Chest, 63, pp.88~92 (1973)
  7. Light RW, "Tuberculous pleural effusions. In: Pleural Diseases", pp.182~119 (2001), Lippincott Williams & Wilkins
  8. Apicella MA, "A physiologic differentiation between delayed and immediate hypersensitivity", J Clin Invest, 48, pp.250~259 (1969)
  9. Leckie WJ, "Albumin turnover in pleural effusions", Clin Sci, 29, pp.339~352 (1965)
  10. Moudgil H, "Reactivation disease: the commonest form of tuberculous pleural effusion in Edinburgh, 1980-1991", Respir Med, 88, pp.301~304 (1994)
  11. Kim HJ, "The prevalence of pulmonary parenchymal tuberculosis in patients with tuberculous pleuritis", Chest, 129, pp.1253~1258 (2006)
  12. Seibert AF, "Tuberculous pleural effusion: twenty-year experience", Chest, 99, pp.883~886 (1991)
  13. Piras MA, "Adenosine deaminase activity in pleural effusions: an aid to differential diagnosis", Br Med J, 2, pp.1751~1752 (1978)
  14. Perez-Rodriguex E, "Effusions from tuberculosis. In Textbook of Pleural Diseases" (2003), Oxford University Press, Inc
  15. Ferrer JS, "Evolution of idiopathic pleural effusion: a prospective, long-term follow-up study", Chest, 109, pp.1508~1513 (1996)
  16. Barnes PF, "Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis", J Immunol, 142, pp.1114~1119 (1989)
  17. Valdés L, "Diagnosis of tuberculous pleurisy using the biologic parameters adenosine deaminase, lysozyme, and interferon gamma", Chest, 103, pp.458~465 (1993)
  18. Greco S, "Adenosine deaminase and interferon gamma measurements for the diagnosis of tuberculous pleurisy: a meta-analysis", Int J Tuberc Lung Dis, 7, pp.777~786 (2003)
  19. Blumberg HM, "American Thoracic Society", Centers for Disease Control and Prevention, Am J Respir Crit Care Med, pp.2003, 167[DOI]
  20. Cañete C, "Tuberculous pleural effusion: experience with six months of treatment with isoniazid and rifampicin", Thorax, 49, pp.1160~1161 (1994)
  21. Dutt AK, "Tuberculous pleural effusion: 6-month therapy with isoniazid and rifampin", Am Rev Respir Dis, 145, pp.1429~1432 (1992)
  22. Lee CH, "Corticosteroids in the treatment of tuberculous pleurisy: a double-blind, placebocontrolled, randomized study", Chest, 94, pp.1256~1259 (1988)
  23. Galarza I, "Randomized trial of corticosteroids in the treatment of tuberculous pleurisy", Thorax, 50, pp.1305~1307 (1995)
  24. Wyser C, "Corticosteroids in the treatment of tuberculous pleurisy: a double-blind, placebo-controlled, randomized study", Chest, 110, pp.333~338 (1996)
  25. Engel ME, "Corticosteroids for tuberculous pleurisy", Cochrane Database Syst Rev 2007:CD001876, ~ (2007)
  26. Lai YF, "Pigtail drainage in the treatment of tuberculous pleural effusions: a randomized study", Thorax, 58, pp.149~151 (2003)
  27. Chung CL, "Early effective drainage in the treatment of loculated tuberculous pleurisy", Eur Respir J, 31, pp.1261~1267 (2008)
  28. Cases Viedma E, "A study of loculated tuberculous pleural effusions treated with intrapleural urokinase", Respir Med, 100, pp.2037~2042 (2006)
  29. Mushegera CK, "Indications and results of pleuropulmonary decortications in the university hospital of Kinshasa", Acta Chir Belg, 96, pp.217~222 (1996)

관련 논문AI추천

심낭 삼출액 환자에서 Adenosine Deaminase를 근거로 한 항결핵 치료 결정의 적합성곽충환, 김나영, 민지현, 박용휘, 박정랑, 안종화, 이은주, 조상영, 황석재, 황진용대한내과학회 · 대한내과학회지2012 · 제82권 제4호소아 결핵성 흉막 유출의 감별진단에서 흉막액 Adenosine Deaminase의 유용성권경호, 김종석, 이균우, 임장훈, 정종수대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2002 · 제12권 제2호Laboratory and radiological discrimination between tuberculous and malignant pleural effusions with high adenosine deaminase levelsChang Ho Kim, Hyewon Seo, Jaehee Lee, Jae Kwang Lim, Jae Yong Park, Ji Eun Park, Sang Yub Lee, Seung Ick Cha, Seung Soo Yoo, Shin Yup Lee, Sun Ha Choi대한내과학회 · The Korean Journal of Internal Medicine2022 · 제37권 제1호결핵성 흉막염으로 오인된 악성중피종김용희, 박소정, 송민주, 양지영, 유정완, 천재경, 최창민영남대학교 의과대학 · Journal of Yeungnam Medical Science2015 · 제32권 제1호증례를 통한 결핵심장막염 진단에서 혈액 및 심장막액 인터페론감마 분비검사의 유용성의 고찰강은숙, 기창석, 박경선, 박형두, 이남용, 장성아대한진단검사의학회 · Laboratory Medicine Online2014 · 제4권 제2호소아에서 결핵에 의한 흉수와 마이코플라즈마 폐렴에 의한 흉수 감별을 위한 흉수 Adenosine Deaminase의 유용성백혜성, 오재원, 이하백, 최재형, 허원경대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2012 · 제22권 제4호

이 간행물의 다른 논문 (15건)