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식이와 비만

Diet and Obesity

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초록

지난 수십 년 동안 식이와 생활 환경 등이 변하여 전 세계적으로 비만의 발생이 증가하고 있다. 최근 우리나라 사람들에서도 비만의 유병률은 증가하고 있으며 지방섭취의 증가도 여러 요인 중의 하나일 수 있다. 비만의 발생은 위 배출능과 위 용적 등의 변화에 기인할 수 있다. 반복적인 고지방식은 위의 기능에 적응성 변화를 초래하여 음식 섭취를 증가시켜 비만을 유발할 수 있다. 향후 특이 영양소 섭취 후 발생하는 위장관의 적응성 변화에 대한 체계적이고 대규모의 연구가 시행되어 비만의 발생 원인을 규명하는 계기가 마련되기를 기대한다.

Abstract

Obesity can be defined as a state of excess body fat or body energy stores in excess of physiological needs. The prevalence of obesity has increased dramatically throughout the world. Despite the greater understanding of the physiologic mechanisms regulating body weight and energy balance, the causes of human obesity poorly understood. Much of human obesity is multifactorial and usually involves relative over-consumption of food. And, consumption of high-fat diets is implicated in the etiology of obesity. Fat-derived energy intake has increased in Korea. Changes in gastric motor and sensory functions can be associated with development of obesity. A High-fat diet may facilitate adaptive changes that contribute to the development of obesity through reduced postprandial satiation in persons with a high baseline maximum tolerated volume. A high fat intake may influences the central control of appetite and behavioral choices in food intake. Further well-controlled large studies with a longer preload duration in Koreans to elucidate the presence and extent of gastrointestinal sensory, motor, absorptive, and behavioral adaptations to diets enriched with specific macronutrients. (Korean J Med 2012;82:291-297)

참고문헌 (66)

  1. Kopelman PG, "Obesity as a medical problem", Nature, 404, pp.635~643 (2000)
  2. Lee JS, "Rapidly increasing prevalence of obesity and their confident determinants in Korea", Korean J Health Educ Promot, 23, pp.1~11 (2006)
  3. "The statistics of life table2008" (2009)[URL]
  4. Larsson B, "Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913", Br Med J (Clin Res Ed), 288, pp.1401~1404 (1984)
  5. Jee SH, "Body mass index and cancer risk in Korean men and women", Int J Cancer, 123, pp.1892~1896 (2008)
  6. Oh SW, "Effects of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea National Health Insurance Corporation Study", J Clin Oncol, 23, pp.4742~4754 (2005)
  7. Jee SH, "Body-mass index and mortality in Korean men and women", N Engl J Med, 355, pp.779~787 (2006)
  8. 이정숙, "과체중 및 비만 여성에서 의학영양치료에 의한 체격지수의 변화 양상 및식사 섭취와 혈액학적 지표의 변화", Journal of Nutrition and Health, 38(6), pp.432~444 (2005), 한국영양학회
  9. Lee K, "Iron nutritional status of female students in Kangnung National University", Korean J Community Nutr, 2, pp.23~32 (1997)
  10. Kleiman S, "Drinking to our health: can beverage companies cut calories while maintaining profits?", Obes Rev (2011)
  11. Monteiro CA, "The snack attack", Am J Public Health, 100, pp.975~981 (2010)
  12. Monteiro C., "The big issue is ultra-processing", World Nutrition, 1, pp.237~259 (2010)
  13. Popkin BM, "The World is Fat-the Fads, Trends, Policies, and Products That are Fattening the Human Race" (2008), Avery-Penguin Group
  14. Mourao DM, "Effects of food form on appetite and energy intake in lean and obese young adults", Int J Obes (Lond), 31, pp.1688~1695 (2007)
  15. Mattes RD, "Dietary compensation by humans for supplemental energy provided as ethanol or carbohydrate in fluids", Physiol Behav, 59, pp.179~187 (1996)
  16. Drewnowski A., "Sweetness and obesity", pp.177~192 (1987), Springer-Verlag
  17. Blundell JE, "Paradoxical effects of an intense sweetener (aspartame) on appetite", Lancet, 1, pp.1092~1093 (1986)
  18. Drewnowski A, "Sensory preferences for fat and sugar in adolescence and adult life", Ann N Y Acad Sci, 561, pp.243~250 (1989)
  19. Malik VS, "Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk", Circulation, 121, pp.1356~1364 (2010)
  20. Kim S, "The nutrition transition in South Korea", Am J Clin Nutr, 71, pp.44~53 (2000)
  21. Moran TH, "Cholecystokinin and satiety: current perspectives", Nutrition, 16, pp.858~865 (2000)
  22. Friedman MI, "Fatty acid oxidation affects food intake by altering hepatic energy status", Am J Physiol, 276(4 Pt 2), pp.1046~1053 (1999)
  23. Park MI, "Gastric motor and sensory functions in obesity", Obes Res, 13, pp.491~500 (2005)
  24. Stadaas J, "Intragastric pressure-volume relationship before and after vagotomy", Acta Chir Scand, 136, pp.611~615 (1970)
  25. Wilbur BG, "Gastrin pentapeptide decreases canine gastric transmural pressure", Gastroenterology, 67, pp.1139~1142 (1974)
  26. Wright RA, "Gastric emptying and obesity", Gastroenterology, 84, pp.747~751 (1983)
  27. Zahorska-Markiewicz B, "Gastric emptying in obesity", Hum Nutr Clin Nutr, 40, pp.309~313 (1986)
  28. Tosetti C, "Gastric emptying of solids in morbid obesity", Int J Obes Relat Metab Disord, 20, pp.200~205 (1996)
  29. Horowitz M, "Abnormalities of gastric emptying in obese patients", Int J Obes, 7, pp.415~421 (1983)
  30. Horowitz M, "Effect of increasing the caloric", osmotic content of the liquid component of a mixed solid and liquid meal on gastric emptying in obese subjects, 1986, pp.40, 51~56
  31. Maddox A, "Gastric and oesophageal emptying in obesity", Scand J Gastroenterol, 24, pp.593~598 (1989)
  32. Jackson SJ, "Delayed gastric emptying in the obese: an assessment using the non-invasive (13) C-octanoic acid breath test", Diabetes Obes Metab, 6, pp.264~270 (2004)
  33. Sasaki H, "Hypergastrinemia in obese noninsulin-dependent diabetes: a possible reflection of high prevalence of vagal dysfunction", J Clin Endocrinol Metab, 56, pp.744~750 (1983)
  34. Barkin JS, "The effects of morbid obesity and the Garren-Edwards gastric bubble on solid phase gastric emptying", Am J Gastroenterol, 83, pp.1364~1367 (1988)
  35. French SJ, "Preliminary studies on the gastrointestinal responses to fatty meals in obese people", Int J Obes Relat Metab Disord, 17, pp.295~300 (1993)
  36. Verdich C, "Effect of obesity and major weight reduction on gastric emptying", Int J Obes Relat Metab Disord, 24, pp.899~905 (2000)
  37. Anand BK, "Activity of single neurones in the hypothalamic feeding centres: effect of gastric distension", J Physiol, 192, pp.63~77 (1967)
  38. Grötzinger U, "Effect of atropine and proximal gastric vagotomy on the acid response to fundic distension in man", Gut, 18, pp.303~310 (1977)
  39. Naeye RL, "The sizes and numbers of cells in visceral organs in human obesity", Am J Clin Pathol, 54, pp.251~253 (1970)
  40. Cox AJ., "Stomach size and its relation to chronic peptic ulcer", AMA Arch Pathol, 54, pp.407~422 (1952)
  41. Granström L, "Stomach distension in extremely obese and in normal subjects", Acta Chir Scand, 151, pp.367~370 (1985)
  42. Geliebter A, "Gastric capacity in normal, obese, and bulimic women", Physiol Behav, 74, pp.743~746 (2001)
  43. Geliebter A, "Effects of strength or aerobic training on body composition, resting metabolic rate, and peak oxygen consumption in obese dieting subjects", Am J Clin Nutr, 66, pp.557~563 (1997)
  44. Klatt S, "Proximal gastric motility functions are normal in severe obesity", Digestion, 58, pp.115~119 (1997)
  45. Chiloiro M, "Gastric emptying in normal weight and obese children: an ultrasound study", Int J Obes Relat Metab Disord, 23, pp.1303~1306 (1999)
  46. Kim DY, "Is there a role for gastric accommodation and satiety in asymptomatic obese people?", Obes Res, 9, pp.655~661 (2001)
  47. Delgado-Aros S, "Independent influences of body mass and gastric volumes on satiation in humans", Gastroenterology, 126, pp.432~440 (2004)
  48. Andrews JM, "Effect of glucose supplementation on appetite and the pyloric motor response to intraduodenal glucose and lipid", Am J Physiol, 274(4 Pt 1), pp.645~652 (1998)
  49. Beckoff K, "Effects of glucose supplementation on gastric emptying, blood glucose homeostasis, and appetite in the elderly", Am J Physiol Regul Integr Comp Physiol, 280, pp.570~576 (2001)
  50. Covasa M, "Adaptation to high-fat diet reduces inhibition of gastric emptying by CCK and intestinal oleate", Am J Physiol Regul Integr Comp Physiol, 278, pp.166~170 (2000)
  51. Covasa M, "Rats maintained on high-fat diets exhibit reduced satiety in response to CCK and bombesin", Peptides, 19, pp.1407~1415 (1998)
  52. Covasa M, "Reduced sensitivity to the satiation effect of intestinal oleate in rats adapted to high-fat diet", Am J Physiol, 277, pp.279~285 (1999)
  53. Cunningham KM, "Gastrointestinal adaptation to diets of differing fat composition in human volunteers", Gut, 32, pp.483~486 (1991)
  54. Cunningham KM, "The effect of short-term dietary supplementation with glucose on gastric emptying in humans", Br J Nutr, 65, pp.15~19 (1991)
  55. Horowitz M, "The effect of short-term dietary supplementation with glucose on gastric emptying of glucose and fructose and oral glucose tolerance in normal subjects", Diabetologia, 39, pp.481~486 (1996)
  56. Sabb JE, "Adaptive response of rat pancreatic lipase to dietary fat: effects of amount and type of fat", J Nutr, 116, pp.892~899 (1986)
  57. Sagher FA, "Rat small intestinal morphology and tissue regulatory peptides: effects of high dietary fat", Br J Nutr, 65, pp.21~28 (1991)
  58. Spannagel AW, "Adaptation to fat markedly increases pancreatic secretory response to intraduodenal fat in rats", Am J Physiol, 270, pp.128~135 (1996)
  59. Shi G, "Specific adaptation of gastric emptying to diets with differing protein content in the rat: is endogenous cholecystokinin implicated?", Gut, 41, pp.612~618 (1997)
  60. Castiglione KE, "Adaptation to high-fat diet accelerates emptying of fat but not carbohydrate test meals in humans", Am J Physiol Regul Integr Comp Physiol, 282, pp.366~371 (2002)
  61. French SJ, "Adaptation to high-fat diets: effects on eating behaviour and plasma cholecystokinin", Br J Nutr, 73, pp.179~189 (1995)
  62. Boyd KA, "High-fat diet effects on gut motility, hormone, and appetite responses to duodenal lipid in healthy men", Am J Physiol Gastrointest Liver Physiol, 284, pp.188~196 (2003)
  63. Park MI, "Effect of different macronutrients in excess on gastric sensory and motor functions and appetite in normal-weight, overweight, and obese humans", Am J Clin Nutr, 85, pp.411~418 (2007)
  64. Tack J, "Janssens J. Role of impaired gastric accommodation to a meal in functional dyspepsia", Gastroenterology, 115, pp.1346~1352 (1998)
  65. Chial HJ, "A nutrient drink test to assess maximum tolerated volume and postprandial symptoms: effects of gender, body mass index and age in health", Neurogastroenterol Motil, 14, pp.249~253 (2002)
  66. Delgado-Aros S, "Effect of gastric volume or emptying on meal-related symptoms after liquid nutrients in obesity: a pharmacologic study", Clin Gastroenterol Hepatol, 3, pp.997~1006 (2005)

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