Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma
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Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltrationof a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenaselevel. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy wasperformed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings andelevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration ofmalignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identifyon imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered asdifferential diagnosis. Early liver biopsy can help to clarify the diagnosis.
Abstract
Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltrationof a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenaselevel. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy wasperformed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings andelevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration ofmalignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identifyon imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered asdifferential diagnosis. Early liver biopsy can help to clarify the diagnosis.
참고문헌 (7)
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