Clinical and Endoscopic Features of Metastatic Tumors in the Stomach Ga
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Background/Aims: Metastasis to the stomach is rare. The aim of this study was to describe and analyze the clinical outcomes of cancers that metastasized to the stomach. Methods: We reviewed the clinicopathological aspects of patients with gastric metastases from solid organ tumors. Thirty-seven cases were identified, and we evaluated the histology, initial presentation, imaging findings, lesion locations, treatment courses, and overall patient survival. Results: Endoscopic findings indicated that solitary lesions presented more frequently than multiple lesions and submucosal tumor-like tumors were the most common appearance. Malignant melanoma was the tumor that most frequently metastasized to the stomach. Twelve patients received treatments after the diagnosis of gastric metastasis. The median survival period from the diagnosis of gastric metastasis was 3.0 months (interquartile range, 1.0 to 11.0 months). Patients with solitary lesions and patients who received any treatments survived longer after the diagnosis of metastatic cancer than patients with multiple lesions and patients who did not any receive any treatments. Conclusions: Proper treatment with careful consideration of the primary tumor characteristics can increase the survival period in patients with tumors that metastasize to the stomach, especially in cases with solitary metastatic lesions in endoscopic findings.
Abstract
Background/Aims: Metastasis to the stomach is rare. The aim of this study was to describe and analyze the clinical outcomes of cancers that metastasized to the stomach. Methods: We reviewed the clinicopathological aspects of patients with gastric metastases from solid organ tumors. Thirty-seven cases were identified, and we evaluated the histology, initial presentation, imaging findings, lesion locations, treatment courses, and overall patient survival. Results: Endoscopic findings indicated that solitary lesions presented more frequently than multiple lesions and submucosal tumor-like tumors were the most common appearance. Malignant melanoma was the tumor that most frequently metastasized to the stomach. Twelve patients received treatments after the diagnosis of gastric metastasis. The median survival period from the diagnosis of gastric metastasis was 3.0 months (interquartile range, 1.0 to 11.0 months). Patients with solitary lesions and patients who received any treatments survived longer after the diagnosis of metastatic cancer than patients with multiple lesions and patients who did not any receive any treatments. Conclusions: Proper treatment with careful consideration of the primary tumor characteristics can increase the survival period in patients with tumors that metastasize to the stomach, especially in cases with solitary metastatic lesions in endoscopic findings.
참고문헌 (15)
- Menuck LS, "Metastatic disease involving the stomach", Am J Dig Dis, 20, pp.903~913 (1975)
- Kadakia SC, "Metastatic tumors to the upper gastrointestinal tract: endoscopic experience", Am J Gastroenterol, 87, pp.1418~1423 (1992)
- Oda, Kondo H, "Metastatic tumors to the stomach: analysis of 54 patients diagnosed at endoscopy and 347 autopsy cases", Endoscopy, 33, pp.507~510 (2001)
- Saito T, "Esophageal carcinoma metastatic to the stomach: a clinicopathologic study of 35 cases", Cancer, 56, pp.2235~2241 (1985)
- Namikawa T, "Clinicopathological features and treatment outcomes of metastatic tumors in the stomach", Surg Today, 44, pp.1392~1399 (2014)
- De Palma GD, "Metastatic tumors to the stomach: clinical and endoscopic features", World J Gastroenterol, 12, pp.7326~7328 (2006)
- Green LK, "Hematogenous metastases to the stomach: a review of 67 cases", Cancer, 65, pp.1596~1600 (1990)
- Taal BG, "The spectrum of gastrointestinal metastases of breast carcinoma: I. stomach", Gastrointest Endosc, 38, pp.130~135 (1992)
- Taal BG, "Clinical presentation, endoscopic features, and treatment of gastric metastases from breast carcinoma", Cancer, 89, pp.2214~2221 (2000)
- Siriwardana HP, "Endoscopic mucosal resection of a solitary metastatic tumor in the stomach: a case report", Surg Laparosc Endosc Percutan Tech, 22, pp.e132~e134 (2012)
- Mi-Young Kim, "Solitary Synchronous Metastatic Gastric Cancer Arising from T1b Renal Cell Carcinoma: A Case Report and Systematic Review", Gut and Liver, 6(3), pp.388~394 (2012), 거트앤리버 발행위원회[DOI]
- Kim YI, "Surgically resected gastric metastasis of pulmonary squamous cell carcinoma", World J Gastrointest Surg, 5, pp.278~281 (2013)
- Reiman T, "Upper gastrointestinal bleeding as a metastatic manifestation of breast cancer: a case report and review of the literature", Can J Gastroenterol, 15, pp.67~71 (2001)
- Hsu CC, "Endoscopic features of metastatic tumors in the upper gastrointestinal tract", Endoscopy, 28, pp.249~253 (1996)
- Campoli PM, "Metastatic cancer to the stomach", Gastric Cancer, 9, pp.19~25 (2006)