림프종과 방선균증으로 의심되던 위장관 발생 IgG4 연관 질환 1례
A Case of IgG4-Related Disease of Gastrointestinal Origin Suspected to be Lymphoma and Actinomyces Infection
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Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by the tendency to form tumefactive lesions. However, the disease has highly variable clinical manifestations, as IgG4-RD can affect any organ. The biliary tree and major salivary glands are commonly affected; however, bowel mucosa is rarely affected. A 41-year-old man presented to our hospital complaining of abdominal pain. Computed tomography and endoscopy were performed at another hospital, and a biopsy was performed on a lesion suspected to be malignant. Biopsy revealed no remarkable findings other than lymphoid hyperplasia. Subsequently, IgG4-RD was confirmed via surgical biopsy. The disease and its symptoms were successfully treated with steroid therapy.
Abstract
Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by the tendency to form tumefactive lesions. However, the disease has highly variable clinical manifestations, as IgG4-RD can affect any organ. The biliary tree and major salivary glands are commonly affected; however, bowel mucosa is rarely affected. A 41-year-old man presented to our hospital complaining of abdominal pain. Computed tomography and endoscopy were performed at another hospital, and a biopsy was performed on a lesion suspected to be malignant. Biopsy revealed no remarkable findings other than lymphoid hyperplasia. Subsequently, IgG4-RD was confirmed via surgical biopsy. The disease and its symptoms were successfully treated with steroid therapy.