대장내시경 후 발생한 급성 인산염 신병증
Sodium Phosphate-Induced Acute Phosphate Nephropathy after Colonoscopy: A Case Report
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Acute phosphate nephropathy is caused by exposure to excess sodium phosphate. Calcium phosphate is deposited in the renal tubular epithelial cells, leading to tubulointerstitial nephritis. We report the case of a 71-year-old female who developed acute kidney injury after undergoing a colonoscopy. She had taken 28 sodium phosphate tablets, equivalent to 42 g of sodium phosphate, as bowel purgatives prior to the colonoscopy. A biopsy of the native kidney revealed acute tubular injury with calcium phosphate deposits. This case report suggests that sodium phosphate tablets can induce acute phosphate nephropathy, particularly in patients with predisposing factors. Therefore, physicians should be vigilant of kidney injury when choosing sodium phosphate as a pre-colonoscopy bowel purgative.
Abstract
Acute phosphate nephropathy is caused by exposure to excess sodium phosphate. Calcium phosphate is deposited in the renal tubular epithelial cells, leading to tubulointerstitial nephritis. We report the case of a 71-year-old female who developed acute kidney injury after undergoing a colonoscopy. She had taken 28 sodium phosphate tablets, equivalent to 42 g of sodium phosphate, as bowel purgatives prior to the colonoscopy. A biopsy of the native kidney revealed acute tubular injury with calcium phosphate deposits. This case report suggests that sodium phosphate tablets can induce acute phosphate nephropathy, particularly in patients with predisposing factors. Therefore, physicians should be vigilant of kidney injury when choosing sodium phosphate as a pre-colonoscopy bowel purgative.