자궁근종이 있는 한국여성에서 자기공명영상 유도하 고집적 초음파수술: 초기 임상경험
Magnetic resonance imaging-guided focused ultrasound surgery for uterine fibroids: Initial experience in Korea
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목적: 본 연구는 자궁근종에 대한 완전한 비침습적 치료인 자기공명영상 유도하 고집적 초음파수술 (MRgFUS)에 대한 안전성 과 효과에 대해 알아보고자 시행되었다. 방법: 증상이 있는 29명의 자궁근종 환자 (평균나이 39.1±5.8세)에서 자기공명영상 유도하 고집적 초음파수술을 시행하였다. 환자들의 증상은 치료 당일, 치료 후 3개월, 6개월 추적검사 시 자궁근종 증상 설문지를 통해 기록하였다. 치료 당일과 추적 검사 시 이상반응에 대해서도 기록하였다. 결과: 치료 후 3개월에 83% 그리고 6개월에 90%의 환자에서 증상의 호전이 있었다. 치료 중이나 치료 후 추적검사 시 환자에 게 심각한 이상반응은 발생하지 않았다. 결론: 본 연구에서 자기공명영상 유도하 고집적 초음파수술은 증상이 있는 자궁근종환자에 있어 증상의 호전을 유도하는 안전 하고도 효과적인 치료법으로 사료된다.
Abstract
Objective: The purpose of this report is to review the safety and short-term efficacy of non-invasive magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) on uterine myomas in Korean women. Methods: A total of 29 outpatient Korean women, whose mean age was 39.1±5.8 years, were treated using the MRgFUS system for their symptomatic uterine myomas. Patients’ symptoms were recorded using a validated symptom-specific questionnaire on treatment day, and at follow-up visits, 3 and 6 months post treatment. Data on adverse events was recorded on each follow up period. Results: Symptom improvement was experienced by 83% of the patients at the three months follow-up, and 90% of the patients reported on improved quality of life by the six months follow-up. There were no serious adverse events during the treatments or the follow-up period. Conclusion: MRgFUS appears to be a safe and effective treatment for symptoms relief of uterine fibroids. Additional reports on longer follow up should verify long-term durability.
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