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아토피피부염 환자 511명의 장기간의 한의학적 치료효과에 대한 후향적 연구

Retrospective Study about the Effectiveness of a long-term Korean Medicine Treatment on 511 Atopic Dermatitis Patients

이정환|조재곤|박건|장진영|정창환|서산|한명화|고영협|한수련
대한한방안이비인후피부과학회 (The Korean Medicine Opthalmology&Otolaryngology&Dermatology Society)|2013.08|한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology&Otorhinolaryngology&Dermatology)|제26권 제3호|pp. 65-76

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키워드

Atopic dermatitisKorean Medicine TreatmentObjective SCORAD Index(OSI)Improvement rate
주제분류한의학

초록

Objective : The purpose of this study is to report the effectiveness of a long-term Korean Medicine Treatment on 511 atopic dermatitis patients. Methods : Total 511 atopic dermatitis patients, who has visited oriental medical clinics from 2011.1.9 to 2012.1.31and continued treatment 3 month to 9 month were analyzed by Objective SCORAD Index(OSI). Subanalysis of OSI were done according to gender, age, treatment period, and intensity. Results : 1. Male and female percent was 42.5:57.5. Age percent was 0 to 11:12 to 18:above 19=30:16.6:53 and 41.9% was steroid users. 2. OSI Improvement rate was significantly higher in women than men after 3 month of treatment, but not significant after 6, 9 month of treatment. 3. There was no improvement difference of OSI among the age. 4. OSI was significantly lower after 3, 6, 9 month of treatment. Average post-treatment score was lowest in 9 month treatment group. 5. 86.7% of total patients reported decrease in OSI score at the final visit. 6. 85.9% was severe, 13.5% was moderate, and 0.6% was mild by OSI intensity assessment at initial visit. The percent changed at final visit to 37% severe, 54.2% moderate, and 8.8% mild. 7. Patient diagnosed as OSI intensity severe at first visit, their average treatment period was 6.58 months and final improvement rate was 36.27%. Conclusion : A significant percent of Atopic dermatitis patients who were treated with Korean Medicine Treatment reported decrease in OSI. There was significant decrease in OSI before and after 3, 6, 9 month treatment. The difference increased with the treatment period.

Abstract

Objective : The purpose of this study is to report the effectiveness of a long-term Korean Medicine Treatment on 511 atopic dermatitis patients. Methods : Total 511 atopic dermatitis patients, who has visited oriental medical clinics from 2011.1.9 to 2012.1.31and continued treatment 3 month to 9 month were analyzed by Objective SCORAD Index(OSI). Subanalysis of OSI were done according to gender, age, treatment period, and intensity. Results : 1. Male and female percent was 42.5:57.5. Age percent was 0 to 11:12 to 18:above 19=30:16.6:53 and 41.9% was steroid users. 2. OSI Improvement rate was significantly higher in women than men after 3 month of treatment, but not significant after 6, 9 month of treatment. 3. There was no improvement difference of OSI among the age. 4. OSI was significantly lower after 3, 6, 9 month of treatment. Average post-treatment score was lowest in 9 month treatment group. 5. 86.7% of total patients reported decrease in OSI score at the final visit. 6. 85.9% was severe, 13.5% was moderate, and 0.6% was mild by OSI intensity assessment at initial visit. The percent changed at final visit to 37% severe, 54.2% moderate, and 8.8% mild. 7. Patient diagnosed as OSI intensity severe at first visit, their average treatment period was 6.58 months and final improvement rate was 36.27%. Conclusion : A significant percent of Atopic dermatitis patients who were treated with Korean Medicine Treatment reported decrease in OSI. There was significant decrease in OSI before and after 3, 6, 9 month treatment. The difference increased with the treatment period.

참고문헌 (29)

  1. Byung Eui Kim, "Epidermal Barrier in Atopic Dermatitis", Allergy, Asthma & Immunology Research, 4(1), pp.12~16 (2012), 대한천식알레르기학회
  2. 이혜영, "인천지역의 유치원 아동의 아토피피부염에 대한 역학적 특징", 대한피부과학회지, 47(2), pp.164~171 (2009), 대한피부과학회
  3. 손정민, "제천 지역 소재 초등학교 학생들의 아토피 피부염에 대한 설문조사 연구", 한방안이비인후피부과학회지, 22(2), pp.163~175 (2009), 대한한방안이비인후피부과학회
  4. Watson W, "Atopic dermatitis", Allergy Asthma Clin Immunol, 7(Suppl 1), pp.S4~ (2011)
  5. Boneberger S, "Complementary therapy for atopic dermatitis and other allergic skin diseases: facts and controversies", Clin Dermatol, 28(1), pp.57~61 (2010)
  6. 서민수, "대한안이비인후피부과학회지에 게재된 아토피 피부염 관련논문에 관한 고찰", 한방안이비인후피부과학회지, 22(3), pp.108~121 (2009), 대한한방안이비인후피부과학회
  7. 김윤희, "한약을 이용한 아토피 임상연구의 경향에 관한 연구", 대한한방소아과학회지, 26(2), pp.53~61 (2012), 대한한방소아과학회
  8. Kobayashi H, "Efficacy and safety of a traditional herbal medicine, Kochu-ekki-to in the Long-term management of Kikyo patients with atopic dermatitis: A 6-month, multicenter, double-blind, randomized, placebo-controlled study", eCAM, 7(3), pp.367~373 (2010)
  9. 최인화, "A Clinical Study of Shi Ho Cheong Gan-San on Blood Heat Pattern Atopic Dermatitis: a randomized, double-blind clinical trial", 한방안이비인후피부과학회지, 24(1), pp.96~110 (2011), 대한한방안이비인후피부과학회
  10. 윤대철, "아토피 피부염 환자에서 黃連解毒湯이 함유된 한방화장품에 대한 임상 연구", 동의생리병리학회지, 22(6), pp.1611~1620 (2008), 대한동의병리학회
  11. 신상호, "升葛湯을 사용한 아토피 피부염 환자에 대한 임상시험", 한방안이비인후피부과학회지, 20(2), pp.199~212 (2007), 대한한방안이비인후피부과학회
  12. Choi IH, "The effect of TJ-15 plus TJ-17 on atopic dermatitis: A pilot study based on the principle of pattern identification", J Altern Complement Med, 18(6), pp.576~582 (2012)
  13. Torrelo A, "Atopic dermatitis: impact on quality of life and patients’ attitudes toward its management", Eur J Dermatol, 22, pp.97~105 (2012)
  14. 박영립, "아토피피부염 학회보고서: 한국인 아토피피부염의 진단기준에 대한 연구", 대한피부과학회지, 44(6), pp.659~663 (2006), 대한피부과학회
  15. Kunz B, "Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis", Dermatol, 195, pp.10~19 (1997)
  16. Rees JL, "Pruritus: more scratch than itch", Clin Exp Dermatol, 24, pp.490~493 (1999)
  17. 권지애, "한국인 청장년기 아토피피부염 환자의 임상적 특징에 관한 연구", 대한피부과학회지, 42(8), pp.949~954 (2004), 대한피부과학회
  18. Chao YF, "Chao Shi Zhy bing Yuan Hou Lun", pp.505~ (1965), Jiwenshuju
  19. Xuekai., "Baoyingquanshu", pp.252~256 (1979), Xinwenfengchubangongsi
  20. Wuqian, "Yizongjinjian", pp.443~444 (1982), Ren Min Wei Sheng Publishing Co
  21. Yang JH, "Western and Traditional Korean approach in Atopic Dermatitis", J Jeahan Orienl Med Acad, 4(1), pp.416~427 (1999)
  22. Hanifin JM, "Diagnostic features of atopic dermatitis", Acta Derm Venereol, 92(Suppl), pp.44~47 (1980)
  23. Gallant C, "A review", J Am Acad Dermatol, 14, pp.161~177 (1986)
  24. Sowden J, "Double-blind, controlled, cross-over study of cyclosporin in adults with severe refractory atopic dermatitis", Lancet, 338, pp.137~140 (1991)
  25. Yun HJ, "A study on the severity scoring systes of atopic dermatitis; comparison, analysis and establishment", J Korean Oriental Med, 23(4), pp.15~26 (2002)
  26. 김효빈, "아토피피부염의 치료 및 관리 실태", 천식 및 알레르기, 32(1), pp.16~20 (2012), 대한천식알레르기학회
  27. 김정희, "아토피피부염의 최신지견", Allergy Asthma & Respiratory Diseases, 14(1), pp.12~23 (2004), 대한 소아알레르기 호흡기학회
  28. Yun HJ, "Clincial study of the classification of oriental medical type of atopic dermatitis", J Dong-Eui Orient Med, 5(1), pp.43~57 (2001)
  29. 고민정, "黃連解毒湯이 아토피 피부염에 미치는 영향에 대한 임상적 연구", 대한한방소아과학회지, 26(4), pp.51~60 (2012), 대한한방소아과학회[DOI]

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