얼굴아토피 피부염환자 45명의 한의학적 치료효과에 대한 후향적 연구
Retrospective Study about the Effectiveness of a Korean Medicine Treatment on 45 Facial Atopic Dermatitis Patients
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective : The purpose of this study is to report the effectiveness of a Korean Medicine Treatment on 45facial atopic dermatitis patients. Methods : Total 45 facial atopic dermatitis patients, who has visited korean medical clinic in year 2011 wereanalyzed by Objective SCORAD Index(OSI) and Investigator’s Global Assessment(IGA). Subanalysis of OSI andIGA were done according to topical ointment user/non-user, treatment period and change in IGA distribution. Results : 1. Male and female percent was 20%:80%. 17.8% were teens, 55.6% were twenties, 13.3% werethirties, 13.3% were above age forty. 64.4% were on topical ointment treatment of corticosteroidor calcineurin inhibitor, and 35.6% were not at the initial visit. Patients with family history were44.4% and 62.2% had atopic dermatitis past history. 2. OSI and IGA were significantly lower after 1~3, 3~6, 6~9 month of treatment. Averagepost-treatment score was lower in longer-treated group. 3. IGA distribution has changed from average 3.42 at the first visit to 1.76 at final visit. 91.1% oftotal patients reported decrease in IGA at the final visit. 4. OSI and IGA improvement rate were significantly higher in non-topical ointment user than theuser. Age, treatment period, initial OSI and IGA score difference were not significantly different. Conclusion : A significant percent of 45 facial atopic dermatitis patients who were treated with Korean Medicine Treatment reported decrease in OSI and IGA. The difference increased with the treatment period. Non-topical ointment users’ improvement was significantly higher than topical ointment user.
Abstract
Objective : The purpose of this study is to report the effectiveness of a Korean Medicine Treatment on 45facial atopic dermatitis patients. Methods : Total 45 facial atopic dermatitis patients, who has visited korean medical clinic in year 2011 wereanalyzed by Objective SCORAD Index(OSI) and Investigator’s Global Assessment(IGA). Subanalysis of OSI andIGA were done according to topical ointment user/non-user, treatment period and change in IGA distribution. Results : 1. Male and female percent was 20%:80%. 17.8% were teens, 55.6% were twenties, 13.3% werethirties, 13.3% were above age forty. 64.4% were on topical ointment treatment of corticosteroidor calcineurin inhibitor, and 35.6% were not at the initial visit. Patients with family history were44.4% and 62.2% had atopic dermatitis past history. 2. OSI and IGA were significantly lower after 1~3, 3~6, 6~9 month of treatment. Averagepost-treatment score was lower in longer-treated group. 3. IGA distribution has changed from average 3.42 at the first visit to 1.76 at final visit. 91.1% oftotal patients reported decrease in IGA at the final visit. 4. OSI and IGA improvement rate were significantly higher in non-topical ointment user than theuser. Age, treatment period, initial OSI and IGA score difference were not significantly different. Conclusion : A significant percent of 45 facial atopic dermatitis patients who were treated with Korean Medicine Treatment reported decrease in OSI and IGA. The difference increased with the treatment period. Non-topical ointment users’ improvement was significantly higher than topical ointment user.
참고문헌 (25)
- Laughter D, "The prevalence of atopic dermatitis in Oregon schoolchildren", J Am Acad Dermatol, 43, pp.649~655 (2000)
- Hong SJ, "Korean ISAAC Study Group of Korean Association of Allergy and Respiratory Diseases. Report of Korean ISAAC epidemiologic study for asthma and allergic diseases in children", Pediatr Allergy Respir Dis, 17(Suppl1), pp.S55~S66 (2007)
- Williams H, "International Study of Asthma and Allergies in Childhood(ISAAC)Phase One and Three Study Groups", Is eczema really on the increase worldwide? J Allergy Clin Immunol, 121, pp.947~954 (2008)
- Leung DY, "New insights into atopic dermatitis", J Clin Invest, 113, pp.651~657 (2004)
- 김희주, "아토피피부염 환자에서 치료 경과에 따른 피부습진 상세부위(습진지도)별 임상양상에 대한 평가", 대한피부과학회지, 50(10), pp.867~873 (2012), 대한피부과학회
- Hong J, "The psychosocial and occupational impact of chronic skin disease", Dermatol Ther, 21, pp.54~59 (2008)
- Zuberbier T, "Long-term management of facial atopic eczema with pimecrolimus cream 1% in paediatric patients with mild to moderate disease", J Eur Acad Dermatol Venereol, 22, pp.718~721 (2008)
- Miyachi Y, "Suplatast", tacrolimus combination therapy for refractory facial erythema in adult patients with atopic dermatitis : a meta-analysis study, 2007, pp.56, 269~275
- Rubel D, "Consensus guidelines for the management of atopic dermatitis : an Asia-Pacific perspective", J Dermatol, 40(3), pp.160~171 (2013)
- Boneberger S, "Complementary therapy for atopic dermatitis and other allergic skin diseases : facts and controversies", Clin Dermatol, 28(1), pp.57~61 (2010)
- 한수련, "아토피피부염 환자 511명의 장기간의 한의학적 치료효과에 대한 후향적 연구", 한방안이비인후피부과학회지, 26(3), pp.65~76 (2013), 대한한방안이비인후피부과학회
- 박영립, "아토피피부염 학회보고서: 한국인 아토피피부염의 진단기준에 대한 연구", 대한피부과학회지, 44(6), pp.659~663 (2006), 대한피부과학회
- Kunz B, "Clinical validation and guidelines for the SCORAD index : consensus report of the European Task Force on Atopic Dermatitis", Dermatol, 195, pp.10~19 (1997)
- 최선영, "아토피피부염의 중증도 평가 방법의 비교", 대한피부과학회지, 51(4), pp.243~248 (2013), 대한피부과학회
- Murrell DF, "A randomized controlled trial of pimecrolimus cream 1% in adolescents and adults with head and neck atopic dermatitis and intolerant of, or dependent on, topical corticosteroids", Br J Dermatol, 157(5), pp.954~959 (2007)
- Hoeger PH, "The treatment of facial atopic dermatitis in children who are intolerant of, or dependent on, topical corticosteroids : a randomized, controlled clinical trial", Br J Dermatol, 160(2), pp.415~422 (2009)
- Huh J, "Donguibogam", pp.470~477 (2005), Donguibogam publisher
- Fitzpatrick TB, "Fitzpatrick's dermatology in general medicine" (2008), McGraw-Hill
- Kim KJ, "A clinical investigation of patients with atopic dermatitis", Korean J Dermatol, 21, pp.171~178 (1983)
- Cooper SM, "Eyelid dermatitis : an evaluation of 232 patch test patients over 5years", Contact Dermatitis, 42, pp.291~293 (2000)
- Feser A, "Periorbital dermatitis : Causes, differential diagnoses and therapy", J Dtsch Dermatol Ges, 8(3), pp.159~166 (2010)
- Temesvari E, "Periocular dermatitis: a report of 401 patients", J Eur Acad Dermatol Venereol, 23(2), pp.124~128 (2009)
- Rapaport MJ, "Corticosteroid addiction and withdrawal in the atopic : the red burning skin syndrome", Clin Dermatol, 21(3), pp.201~214 (2003)
- Park G, "Atopic revolution", pp.172~189 (2011), Freehug publisher
- 서민수, "대한안이비인후피부과학회지에 게재된 아토피 피부염 관련논문에 관한 고찰", 한방안이비인후피부과학회지, 22(3), pp.108~121 (2009), 대한한방안이비인후피부과학회