영유아 아토피피부염 환자 69명의 한의학적 치료효과에 대한 후향적 연구
Retrospective Study about the Effectiveness of a Korean Medicine Treatment on 69 Infant and Young Child Atopic Dermatitis Patients
0
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
ObjectivesThe purpose of this study is to report the effectiveness of Korean medicine treatment on 69 infant and youngchild atopic dermatitis patients. Methods69 infants and young child atopic dermatitis patients who had visited oriental medical clinics from 2011.1.9 to2012.1.31 were studied. All of them were continually treated for 3 to 9 months, and were analyzed by ObjectiveSCORAD Index (OSI). A detailed analysis of OSI was done according to gender, age, using of topical steroidointment, family history of atopic disease, treatment period, and intensity. Results1. Male and female percentage of the study group was 56.5%: 43.5%. The average period of treatment was 6.09months. 71.0% used topical steroid ointment, and 65.2% had family history of atopic disease. 2. The average period of treatment was significantly longer in patients who used topical steroid ointment, or whohad family history of atopic disease. 3. 95.7% of total patients reported decrease in OSI score at the final visit. OSI was significantly lowered after3, 6, and 9 months of treatment. The longer period of treatment, the lower average post-treatment OSI. 4. 85.5% of the study group had severe dermatitis, and 14.5% was moderate case based on the OSI intensityassessment at initial visit. These percentages got changed at the final visit as 34.8% of severe, 58.0% ofmoderate, and 7.2% of mild cases. The average treatment period of patients who were diagnosed as severe atthe initial visit was 6.18 months, and their final OSI improvement rate was 39.58%. 58% of them wereimproved to be mild or moderate at the final visit. ConclusionThe Korean medicine treatment is effective in treating infant and young child atopic dermatitis patients. Therewas significant decrease in OSI score after 3, 6, and 9 months of treatment. The difference increase with thetreatment period.
Abstract
ObjectivesThe purpose of this study is to report the effectiveness of Korean medicine treatment on 69 infant and youngchild atopic dermatitis patients. Methods69 infants and young child atopic dermatitis patients who had visited oriental medical clinics from 2011.1.9 to2012.1.31 were studied. All of them were continually treated for 3 to 9 months, and were analyzed by ObjectiveSCORAD Index (OSI). A detailed analysis of OSI was done according to gender, age, using of topical steroidointment, family history of atopic disease, treatment period, and intensity. Results1. Male and female percentage of the study group was 56.5%: 43.5%. The average period of treatment was 6.09months. 71.0% used topical steroid ointment, and 65.2% had family history of atopic disease. 2. The average period of treatment was significantly longer in patients who used topical steroid ointment, or whohad family history of atopic disease. 3. 95.7% of total patients reported decrease in OSI score at the final visit. OSI was significantly lowered after3, 6, and 9 months of treatment. The longer period of treatment, the lower average post-treatment OSI. 4. 85.5% of the study group had severe dermatitis, and 14.5% was moderate case based on the OSI intensityassessment at initial visit. These percentages got changed at the final visit as 34.8% of severe, 58.0% ofmoderate, and 7.2% of mild cases. The average treatment period of patients who were diagnosed as severe atthe initial visit was 6.18 months, and their final OSI improvement rate was 39.58%. 58% of them wereimproved to be mild or moderate at the final visit. ConclusionThe Korean medicine treatment is effective in treating infant and young child atopic dermatitis patients. Therewas significant decrease in OSI score after 3, 6, and 9 months of treatment. The difference increase with thetreatment period.
참고문헌 (57)
- Bohme M, "Clinical features of atopic dermatitis at two years of age : a prospective, population-based case-control study", Acta Derm Venereol, 81(3), pp.193~197 (2001)
- 편복양, "영유아 아토피피부염의 위험 인자", Allergy Asthma & Respiratory Diseases, 15(3), pp.235~237 (2005), 대한 소아알레르기 호흡기학회
- Clark RA, "Atopic dermatitis. In: Sams WM, Lynch PJ, eds. Principles and practice of dermatology", pp.403~418 (1996), Churchill Linvingston
- Korea National Health and Nutrition Examination Survey (KNHANES Ⅳ-3), "Ministry of Health and Welfare & Korea Center for Disease Control and Prevention", ~ (2010)
- American Academy of Pediatrics, "Developmental surveillance and screening of infants and young children", Pediatrics, 108(1), pp.192~196 (2001)
- 조여원, "아토피피부염 영아에서 유아식 유형에 따른 임상증상, 영양상태 및 면역 지표의 변화", 천식 및 알레르기, 27(1), pp.33~42 (2007), 대한천식알레르기학회
- Daud LR, "Psychosocial adjustment in preschool children with atopic eczema", Arch Dis Child, 69(6), pp.670~676 (1993)
- 박창근, "유?소아기 아토피피부염이 환아의 삶의 질과 가족에 미치는 영향", 대한피부과학회지, 45(5), pp.429~438 (2007), 대한피부과학회
- Watson W, "Atopic dermatitis", Allergy Asthma Clin Immunol, 7(suppl 1), pp.S4~ (2011)
- Gallant C, "Oral glucocorticoids and their complications. A review", J Am Acad Dermatol, 14(2pt 1), pp.161~177 (1986)
- Sowden JM, "Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis", Lancet, 338(8760), pp.137~140 (1991)
- 김태윤, "아토피피부염 치료의 최신 경향", Allergy Asthma & Respiratory Diseases, 19(3), pp.209~219 (2009), 대한 소아알레르기 호흡기학회
- 서민수, "대한안이비인후피부과학회지에 게재된 아토피 피부염 관련논문에 관한 고찰", 한방안이비인후피부과학회지, 22(3), pp.108~121 (2009), 대한한방안이비인후피부과학회
- Korean Dermatological Association Textbook Compilation Committee, "Dermatology", pp.170~ (2008), Ryomoongak P Co
- 신미란, "캠프 형식의 입원 치료를 받은 소아 아토피피부염 환자 6례", 대한한방소아과학회지, 28(2), pp.40~55 (2014), 대한한방소아과학회
- 고민정, "黃連解毒湯이 아토피 피부염에 미치는 영향에 대한 임상적 연구", 대한한방소아과학회지, 26(4), pp.51~60 (2012), 대한한방소아과학회[DOI]
- 조민서, "한방 병원 소아과를 내원한 소아 아토피 피부염 환자 실태에 관한 조사", 대한한방소아과학회지, 25(2), pp.8~14 (2011), 대한한방소아과학회
- 유현영, "生血潤膚飮을 이용한 아토피 피부염 치험례 보고", 대한한방소아과학회지, 22(1), pp.35~48 (2008), 대한한방소아과학회
- 송현지, "加味淸心蓮子湯의 아토피 피부염 치료에 대한 임상고찰", 대한한방소아과학회지, 21(3), pp.21~31 (2007), 대한한방소아과학회
- 박영립, "아토피피부염 학회보고서: 한국인 아토피피부염의 진단기준에 대한 연구", 대한피부과학회지, 44(6), pp.659~663 (2006), 대한피부과학회
- Stalder JF, "Severity scoring of atopic dermatitis:the SCORAD index. consensus report of the european task force on atopic dermatitis", Dermatol, 186(1), pp.23~31 (1993)
- Kim KB, "Hanbangsoacheongsonyeonuihak", pp.185~751 (2010), Ui Sung Dang Publishing Co
- Wu Q., "Yi Zong Jin Jian, Vol 3", pp.443~452 (1982), Ren Min Wei Sheng Publishing Co
- Chao YF, "Chao Shi Zhu Bing Yuan Hou Lun", pp.505~ (1965), Jiwenshuju
- Xuekai, "Baoyingquanshu", pp.252~256 (1979), Xinwenfengchubangongsi
- Lewis-Jones MS, "The children's dermatology life quality index(CDLQI) : initial validation and practical use", Br J Dermatol, 132(6), pp.942~949 (1995)
- Howlett S., "Emotional dysfunction, child-family relation ships and childhood atopic dermatitis", Br J Dermatol, 140(3), pp.381~384 (1999)
- Lapidus CS, "Social impact of atopic dermatitis", Med Health R I, 84(9), pp.294~295 (2001)
- 김혜성, "아토피피부염의 치료", 대한의사협회지, 57(3), pp.226~233 (2014), 대한의사협회[DOI]
- Krakowski AC, "Management of atopic dermatitis in the pediatric population", Pediatrics, 122(4), pp.812~824 (2008)
- Nicol NH, "Successful strategies in atopic dermatitis management", Dermatol Nurs, (Suppl), pp.3~18 (2008)
- 강경화, "일개 대학병원 아토피피부염 환아의 병원 치료 및 대체보완요법 이용 양상과 치료비용", Allergy Asthma & Respiratory Diseases, 22(1), pp.27~36 (2012), 대한 소아알레르기 호흡기학회[DOI]
- Wang T, "Wai Tai Mi Yao", pp.72~ (1996), Ren Min Wei Sheng Publishing Co
- Yoon KY, "Dongyui-imsangbangjehak", pp.228~229 (1985), Myungbo Publishing Co
- Park HS, "Imsangcheobang-gangjwa", pp.167~171 (2000), Daesung Publishing Co
- Jeong JM, "Zhongyuicheobanghaesul·imsang·eungyong", pp.354~357 (1992), Gyechuk Munwhasa
- Yun YG, "Dohaejeungbo Dongyuibangjewachubanghaesul", pp.730~746 (2007), Ui Sung Dang Publishing Co
- Shin MG, "Imsangbonchohak", pp.252~791 (2002), Yeong Rim Sa Publishing Co
- 진영아, "영유아 아토피피부염에서 항원감작 및 가족력, 섭식력에 대한 연구", Allergy Asthma & Respiratory Diseases, 13(3), pp.180~188 (2003), 대한 소아알레르기 호흡기학회
- 안소현, "생후 6개월 이하의 중등증 및 중증아토피피부염 환자에서 위험요인 분석", Allergy Asthma & Respiratory Diseases, 15(3), pp.242~249 (2005), 대한 소아알레르기 호흡기학회
- 김방실, "아토피 피부염 환자에서 12 주간의 심층 영양관리에 따른 식사의 질과 혈중 지방산조성 및 면역지표에 관한연구", 대한지역사회영양학회지, 13(1), pp.80~90 (2008), 대한지역사회영양학회
- Mailhol C, "Prevalence and risk factors for allergic contact dermatitis to topical treatment in atopic dermatitis : a study in 641 children", Allergy, 64(5), pp.801~806 (2009)
- 김혜영, "알레르기 가족력이 영아기 아토피피부염 발생에 미치는 영향", Allergy Asthma & Respiratory Diseases, 19(2), pp.106~114 (2009), 대한 소아알레르기 호흡기학회
- 김정희, "아토피피부염의 최신지견", Allergy Asthma & Respiratory Diseases, 14(1), pp.12~23 (2004), 대한 소아알레르기 호흡기학회
- Yun HJ, "Clinical study of atopic dermatitis;the classification of oriental medical clinical type and treatment", J Korean Orient Med, 22(2), pp.10~21 (2001)
- Rapaport MJ, "Corticosteroid addiction and withdrawal in the atopic : the red burning skin syndrome", Clin Dermatol, 21(3), pp.201~214 (2003)
- Park G., "The revolution of atopy (The second volume)", pp.19~189 (2011), Freehug Publisher
- Hill CJ, "Adverse effects from topical steroids", Cutis, 21(5), pp.624~628 (1978)
- Ruiz-Maldonado R, "Cushing's syndrome after topical application of corticosteroids", Am J Dis Child, 136(3), pp.274~275 (1982)
- McLean CJ, "Cataracts glaucoma and femoral avascular necrosis caused by topical corticosteroid ointment", Lancet, 345(8945), pp.330~ (1995)
- Bode HH, "Dwarfism following long-term topical corticosteroid therapy", JAMA, 244(8), pp.813~814 (1980)
- Queille C, "Efficacy versus systemic effects of six topical steroids in the treatment of atopic dermatitis of childhood", Pediatr Dermatol, 1(3), pp.246~253 (1984)
- 김동희, "소아의 아토피피부염 관리 실태", Allergy Asthma & Respiratory Diseases, 18(2), pp.39~48 (2008), 대한 소아알레르기 호흡기학회
- Kunz B, "Clinical validation and guidelines for the SCORAD index : consensus report of the european task force on atopic dermatitis", Dermatology, 195(1), pp.10~19 (1997)
- 김동하, "아토피피부염에 대한 환자의 인식도 설문조사 연구", 대한피부과학회지, 50(3), pp.201~211 (2012), 대한피부과학회
- Cho SH, "Atopic dermatitis in korean", J Korean Med Assoc, 57(3), pp.205~207 (2014)
- 이지현, "아토피피부염학회 보고서: 한국 아토피피부염의 치료지침", 대한피부과학회지, 44(8), pp.907~913 (2006), 대한피부과학회
