영유아 아토피피부염 환자의 스테로이드 외용제 사용유무에 따른 한의학적 치료효과에 대한 후향적 연구
Retrospective Study of the Effectiveness of Korean Medical Treatment on Infant and Young Child Atopic Dermatitis Patients with or without Topical Co-administration of Steroid.
0
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Objectives: The purpose of this study is to examine whether there is a significant efficacy difference on infant and young child atopic dermatitis patients treated with Korean Medicine Treatment through 6 months between topical steroid used group and non-steroid group. Methods: The degree of atopic dermatitis was measured by the Objective SCORAD Index (OSI) with photographs of patients. Detailed analysis of the OSI score was compared based on the use of topical steroid. Results: 1. There was not a significant difference between the topical steroid group and the non-steroid group in regards of gender, age and initial OSI score. 2. The non-steroid group’s OSI score decreased significantly from 50.17 to 29.20. 3. The topical steroid group’s OSI score decreased significantly from 54.21 to 34.95. 76.19% of the patients in the topical steroid group discontinued steroid use within the 6-month period. The average time of discontinuation since the beginning of treatment was 3.36 months. 4. The OSI Improvement rate comparison of topical steroid group with non-steroid group did not show a significant difference over a 3-month and 6-month period. 5. Distribution of severe cases decreased in Both topical steroid and non-steroid group after 6 month treatment. Conclusions: The OSI score of infant and young child atopic dermatitis patients in both topical steroid and non-steroid group was decreased significantly with Korean medicine treatment through 6 months. There was no significant difference between topical steroid group and non-steroid group in OSI improvements over a 3-month period and 6-month period.
Abstract
Objectives: The purpose of this study is to examine whether there is a significant efficacy difference on infant and young child atopic dermatitis patients treated with Korean Medicine Treatment through 6 months between topical steroid used group and non-steroid group. Methods: The degree of atopic dermatitis was measured by the Objective SCORAD Index (OSI) with photographs of patients. Detailed analysis of the OSI score was compared based on the use of topical steroid. Results: 1. There was not a significant difference between the topical steroid group and the non-steroid group in regards of gender, age and initial OSI score. 2. The non-steroid group’s OSI score decreased significantly from 50.17 to 29.20. 3. The topical steroid group’s OSI score decreased significantly from 54.21 to 34.95. 76.19% of the patients in the topical steroid group discontinued steroid use within the 6-month period. The average time of discontinuation since the beginning of treatment was 3.36 months. 4. The OSI Improvement rate comparison of topical steroid group with non-steroid group did not show a significant difference over a 3-month and 6-month period. 5. Distribution of severe cases decreased in Both topical steroid and non-steroid group after 6 month treatment. Conclusions: The OSI score of infant and young child atopic dermatitis patients in both topical steroid and non-steroid group was decreased significantly with Korean medicine treatment through 6 months. There was no significant difference between topical steroid group and non-steroid group in OSI improvements over a 3-month period and 6-month period.
참고문헌 (31)
- Pyun BY, "Relationship between Atopic Dermatitis, Wheezing during Infancy and Asthma Development", J Korean Med Assoc, 50(6), pp.533~538 (2007)
- The Korean Academy of Family Medicine, "Textbook Of Family Medicine(The second volume)", pp.1265~1267 (2010), Hankookbook Publishing, Inc
- 유일영, "아토피 피부염 환아 어머니의 양육 스트레스와 간호 요구", Child Health Nursing Research, 10(4), pp.423~430 (2004), 한국아동간호학회
- 박승주, "아토피피부염 유병여부에 따른 영유아의 영양섭취와 성장 비교 연구", 대한지역사회영양학회지, 17(3), pp.271~279 (2012), 대한지역사회영양학회[DOI]
- 김혜성, "아토피피부염의 치료", 대한의사협회지, 57(3), pp.226~233 (2014), 대한의사협회[DOI]
- Kalavala M, "Calcineurin inhibitors in pediatric atopic dermatitis : a review of current evidence", Am J Clin Dermatol, 12(1), pp.15~24 (2011)
- Cho SH, "Atopic dermatitis in Korean", J Korean Med Assoc, 57(3), pp.205~207 (2014)
- 손창규, "아토피 환자의 치료선택 경향에 대한 설문연구", 한방안이비인후피부과학회지, 27(1), pp.37~44 (2014), 대한한방안이비인후피부과학회
- 조민서, "한방 병원 소아과를 내원한 소아 아토피 피부염 환자 실태에 관한 조사", 대한한방소아과학회지, 25(2), pp.8~14 (2011), 대한한방소아과학회
- 박영립, "아토피피부염 학회보고서: 한국인 아토피피부염의 진단기준에 대한 연구", 대한피부과학회지, 44(6), pp.659~663 (2006), 대한피부과학회
- 김정은, "Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): General Management and Topical Treatment", Annals of Dermatology, 27(5), pp.563~577 (2015), 대한피부과학회
- European Task Force on Atopic Dermatitis, "Severity Scoring of Atopic Dermatitis : The SCORAD Index, consensus report of the European Task Force on Atopic Dermatitis", Dermatology, 186(1), pp.23~31 (1993)
- 이동훈, "아토피피부염 치료 실태에 관한 다기관 설문조사", Allergy Asthma & Respiratory Diseases, 4(4), pp.271~275 (2016), 대한 소아알레르기 호흡기학회[DOI]
- Akdis CA, "Diagnosis and treatment of atopic dermatitis in children and adults : European Academy of Allergology and Clinical Immunology", American Academy of Allergy, Asthma and Immunology, J Allergy Clin Immunol, pp.2006, 118(1)[DOI]
- Krakowski AC, "Management of atopic dermatitis in the pediatric population", Pediatrics, 122(4), pp.812~824 (2008)
- Nicol NH, "Successful strategies in atopic dermatitis management", Dermatol Nurs, (Suppl:3), pp.3~18 (2008)
- Reitamo S, "An update on current pharmacotherapy options in atopic dermatitis", Expert Opin Pharmacother, 15(11), pp.1517~1524 (2014)
- Darsow U, "Difficult to control atopic dermatitis", World Allergy Organ J, 6(1), pp.6~ (2013)
- Furue M, "Current status of atopic dermatitis in Japan", Asia Pac Allergy, 1(2), pp.64~72 (2011)
- Kojima R, "Factors associated with steroid phobia in caregivers of children with atopic dermatitis", Pediatr Dermatol, 30(1), pp.29~35 (2013)
- 서민수, "대한안이비인후피부과학회지에 게재된 아토피 피부염 관련논문에 관한 고찰", 한방안이비인후피부과학회지, 22(3), pp.108~121 (2009), 대한한방안이비인후피부과학회
- 김세연, "국소 스테로이드 제제 사용에 관한 대학 병원 피부과외래 환자의 인식도 및 행태 설문 조사", 대한피부과학회지, 46(4), pp.473~479 (2008), 대한피부과학회
- Aschoff R, "Evaluation of the atrophogenic potential of hydrocortisone 1%cream and pimecrolimus 1% cream in uninvolved forehead skin patients with atopic dermatitis using optical coherence tomography", Exp Dermatol, 20(10), pp.832~836 (2011)
- Rapaport MJ, "Corticosteroid addiction and withdrawal in the atopic : the red burning skin syndrome", Clin Dermatol, 21(3), pp.201~214 (2003)
- Ben-Gashir MA, "Quality of life and disease severity are correlated in children with atopic dermatitis", Br J Dermatol, 150(2), pp.284~290 (2004)
- Gupta MA, "Depression modulates pruritus perception : a study of pruritus in psoriasis, atopic dermatitis, and chronic idiopathic urticaria", Psychosom Med, 56(1), pp.36~40 (1994)
- 김동희, "소아의 아토피피부염 관리 실태", Allergy Asthma & Respiratory Diseases, 18(2), pp.39~48 (2008), 대한 소아알레르기 호흡기학회
- Park G, "The revolution of atopy(2nd vol)", pp.19~22 (2011), Freehug Publisher
- Park HS, "Five Cases of Atopic Dermatitis", J Korean Orient Med Ophtahlmol Otolaryngol Dermatol, 16(2), pp.255~260 (2003)
- Jung JY, "Three Cases of Atopic Dermatitis", J Korean Orient Med Ophtahlmol Otolaryngol Dermatol, 17(2), pp.131~139 (2004)
- 송현지, "加味淸心蓮子湯의 아토피 피부염 치료에 대한 임상고찰", 대한한방소아과학회지, 21(3), pp.21~31 (2007), 대한한방소아과학회