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The Effect of Pulsatile Flow on Ultrafiltration: In-Vitro Study and Comparison with Roller Pump

J. H. Jeong|K. Lee|C. H. Mun|J. C. Lee|B. G. Min
대한의용생체공학회 (The Korea Society Of Medical & Biological Engineering)|2005.10|의공학회지 (Journal of biomedical Engineering Research)|제26권 제5호|pp. 337-341

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Abstract

Blood pulsation has been reported to have an advantageous effect on extracorporeal blood circulation. However, the study of pulsatile blood flow in renal replacement therapy is very limited. The in-vitro experimental results of pulsatile blood flow on ultrafiltration, when compared with the conventional roller pump, are described in this paper. Methods: Blood flow rate (QB) and transmembrane pressure (TMP) were considered as regulating factors that have an influence on ultrafiltration. Experiments were performed under the condition of equal TMP and QB in both pulsatile and roller pump groups. Several kinds of hollow fiber dialyzers were tested using distilled water containing chemicals as a blood substitute. Mean TMP (mTMP) varied from 10 to 90 mmHg while the QB was 200 ml/min. Results: Ultrafiltration rate (QUF) was found to be linearly proportional to TMP, whereas QB had little influence on QUF. In addition, QUF was higher in the pulsatile group than the roller pump group at the identical TMP. Conclusion: In the controlled test, QUF increased solely as a consequence of blood pulsation, which implies that the pulse frequency represents an additional and important clinical variable during renal replacement therapy.

참고문헌 (25)

  1. "Comparative studies of pulsatile and nonpulsatile flow during cardiopulmonary bypass. II. The effects on adrenal secretion of cortisol", 75, pp.574~8 (1978)
  2. "Pulsatile flow during routine cardiopulmonary bypass", 25, pp.530~6 (1984)
  3. "Results of open heart surgery in patients with impaired renal function as creatinine clearance below 30 ml", min. The effects of pulsatile perfusion, 1986., pp.27, 595~9
  4. "Effects of pulsatile and nonpulsatile perfusion mode during extracorporeal circulation--a comparative clinical study", 40, pp.345~51 (1992)
  5. "The effects of pulsatile versus nonpulsatile perfusion on blood viscoelasticity before and after deep hypothermic circulatory arrest in a neonatal piglet model", 23, pp.717~721 (1999)
  6. "Effect of pulsatile and nonpulsatile assist on heart and kidney microcirculation with cardiogenic shock", 20, pp.681~684 (1996)
  7. "Renal circulation and cellular metabolism during left ventricular assisted circulation comparison study of pulsatile and nonpulsatile assists", 21, pp.830~835 (1997)
  8. "Microcirculation of kidney and skin during left ventricular assisted circulation--comparative studies of pulsatile and nonpulsatile assists", 46, pp.1239~1246 (1998)
  9. "Cytokine and endothelial damage in pulsatile and nonpulsatile cardiopulmonary bypass", 23, pp.508~512 (1999)
  10. "Physiologic principles and urea kinetic modeling. In: Daugirdas JT, Blake PG, Ing TS, eds. Handbook of dialysis", pp.15~45 (2000), Lippincott Williams & Wilkins
  11. "Biophysics of ultrafiltration and hemofiltration. In eds. Replacement of Renal Function By Dialysis", pp.113~145 (1996), Boston Kluwer Academic Publishers
  12. "Solute clearances during continuous venovenous haemofiltration at various ultrafiltration flow rates using Multiflow-100 and HF1000 filters", 18, pp.961~966 (2003)
  13. "On-line mixed hemodiafiltration with a feedback for ultrafiltration control:effect on middle-molecule removal", 64, pp.1505~1513 (2003)
  14. "evidence of enhanced molecular clearance and ultrafiltration volume by using pulsatile flow", 16, pp.645~52 (1993)
  15. "Continuous venovenous renal replacement therapy using a pulsatile blood pump", 18, pp.29~32 (2003)
  16. "Applications of the pulsatile flow versatile ECLS", 26, pp.428~435 (2003)
  17. "Defining pulsatile perfusion:quantification in terms of energy equivalent pressure", 24, pp.712~716 (1999)
  18. "Pulsatile perfusion improves regional myocardial blood flow during and after hypothermic cardiopulmonary bypass in a neonatal piglet model", 48, pp.90~95 (2002)
  19. "Pulsatile and nonpulsatile flows can be quantified in terms of energy equivalent pressure during cardiopulmonary bypass for direct comparisons", 45, pp.610~614 (1999)
  20. "Influence of pulsatile and nonpulsatile left heart bypass on the hormonal circadian rhythm", 47, pp.305~307 (2001)
  21. "The alphabet of research on pulsatile and nonpulsatile perfusion during chronic support", 26, pp.812~813 (2002)
  22. "Fundamentals of pulsatile versus nonpulsatile flow during chronic support", 49, pp.139~140 (2003)
  23. "Energy equivalent pressure formula is for precise quantification of different perfusion modes", 76, pp.1777~1778 (2003)
  24. "Controversy over the benefits of pulsatile perfusion", 27, pp.509~510 (2004)
  25. "Polymetric Membranes for Medical applications", 75, pp.1725~1732 (2003)

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