Efficacy and Safety of Hair Removal with a Long-Pulsed Diode Laser Depending on the Spot Size: A Randomized, Evaluators-Blinded, Left-Right Study
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background: The efficacy of the long-pulsed diode laser (LPDL) in hair removal is determined with various physical parameters. Recently, LPDLs with a larger spot size are commercially available; however, the independent effect of spot size on hair removal has not been studied. Objective:This study aimed to compare the efficacy of the LPDL in hair removal depending on the spot size. Methods: A randomized, evaluators-blind, intrapatient comparison (left vs. right) trial was designed. Ten healthy Korean women received three hair removal treatment sessions on both armpits with the 805-nm LPDL and followed for 3 months. A 10×10 mm handpiece (D1) or a 10×30 mm handpiece (D3) was randomly assigned to the right or left axilla. The fluence, pulse duration, and epidermal cooling temperature were identical for both armpits. Hair clearance was quantified with highresolution photos taken at each visit. Postprocedural pain was quantified on a visual analogue scale. Adverse events were evaluated by physical examination and the patients’ self-report. Results: The mean hair clearance at 3 months after three treatment sessions was 38.7% and 50.1% on the armpits treated with D1 and D3, respectively (p=0.028). Procedural pain was significantly greater in the side treated with D3 (p=0.009). Serious adverse events were not observed. Conclusion: Given that the pulse duration, fluence, and epidermal cooling were identical, the 805-nm LPDL at the three times larger spot size showed an efficacy improvement of 29.5% in axillary hair removal without serious adverse events.
Abstract
Background: The efficacy of the long-pulsed diode laser (LPDL) in hair removal is determined with various physical parameters. Recently, LPDLs with a larger spot size are commercially available; however, the independent effect of spot size on hair removal has not been studied. Objective:This study aimed to compare the efficacy of the LPDL in hair removal depending on the spot size. Methods: A randomized, evaluators-blind, intrapatient comparison (left vs. right) trial was designed. Ten healthy Korean women received three hair removal treatment sessions on both armpits with the 805-nm LPDL and followed for 3 months. A 10×10 mm handpiece (D1) or a 10×30 mm handpiece (D3) was randomly assigned to the right or left axilla. The fluence, pulse duration, and epidermal cooling temperature were identical for both armpits. Hair clearance was quantified with highresolution photos taken at each visit. Postprocedural pain was quantified on a visual analogue scale. Adverse events were evaluated by physical examination and the patients’ self-report. Results: The mean hair clearance at 3 months after three treatment sessions was 38.7% and 50.1% on the armpits treated with D1 and D3, respectively (p=0.028). Procedural pain was significantly greater in the side treated with D3 (p=0.009). Serious adverse events were not observed. Conclusion: Given that the pulse duration, fluence, and epidermal cooling were identical, the 805-nm LPDL at the three times larger spot size showed an efficacy improvement of 29.5% in axillary hair removal without serious adverse events.
참고문헌 (22)
- Sung Hyub Han, "Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Result of a Prospective, Multicenter Study", Annals of Dermatology, 24(3), pp.311~318 (2012), 대한피부과학회[DOI]
- Grossman MC, "Damage to hair follicles by normal-mode ruby laser pulses", J Am Acad Dermatol, 35, pp.889~894 (1996)
- Gan SD, "Laser hair removal: a review", Dermatol Surg, 39, pp.823~838 (2013)
- Baugh WP, "Hair reduction using a scanning 800 nm diode laser", Dermatol Surg, 27, pp.358~364 (2001)
- Campos VB, "Hair removal with an 800-nm pulsed diode laser", J Am Acad Dermatol, 43, pp.442~447 (2000)
- Royo J, "Six-month follow-up multicenter prospective study of 368 patients, phototypes III to V, on epilation efficacy using an 810-nm diode laser at low fluence", Lasers Med Sci, 26, pp.247~255 (2011)
- Ilknur T, "Effects of the 810-nm diode laser on hair and on the biophysical properties of skin", J Cosmet Laser Ther, 12, pp.269~275 (2010)
- Chan HH, "An in vivo study comparing the efficacy and complications of diode laser and long-pulsed Nd:YAG laser in hair removal in Chinese patients", Dermatol Surg, 27, pp.950~954 (2001)
- Ibrahimi OA, "Long-term clinical evaluation of a 800-nm long-pulsed diode laser with a large spot size and vacuum-assisted suction for hair removal", Dermatol Surg, 38, pp.912~917 (2012)
- Pai GS, "Safety and efficacy of low-fluence, high-repetition rate versus high-fluence, lowrepetition rate 810-nm diode laser for permanent hair removal--a split-face comparison study", J Cosmet Laser Ther, 13, pp.134~137 (2011)
- Galadari I, "Comparative evaluation of different hair removal lasers in skin types IV, V, and VI", Int J Dermatol, 42, pp.68~70 (2003)
- Rogachefsky AS, "Evaluation of a new super-long-pulsed 810 nm diode laser for the removal of unwanted hair: the concept of thermal damage time", Dermatol Surg, 28, pp.410~414 (2002)
- Altshuler GB, "Extended theory of selective photothermolysis", Lasers Surg Med, 29, pp.416~432 (2001)
- Lou WW, "Prospective study of hair reduction by diode laser (800 nm)with long-term follow-up", Dermatol Surg, 26, pp.428~432 (2000)
- Bäumler W, "The effect of different spot sizes on the efficacy of hair removal using a long-pulsed diode laser", Dermatol Surg, 28, pp.118~121 (2002)
- Anderson RR, "Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation", Science, 220, pp.524~527 (1983)
- Eremia S, "Topical anesthesia for laser hair removal:comparison of spot sizes and 755 nm versus 800 nm wavelengths", Dermatol Surg, 26, pp.667~669 (2000)
- Ross EV, "Theoretical considerations in laser hair removal", Dermatol Clin, 17, pp.333~355 (1999)
- Littler CM, "Hair removal using an Nd:YAG laser system", Dermatol Clin, 17, pp.401~430 (1999)
- Nouri K, "Comparing 18-versus 12-mm spot size in hair removal using a gentlease 755-nm alexandrite laser", Dermatol Surg, 30, pp.494~497 (2004)
- Klein A, "Photoepilation with a diode laser vs. intense pulsed light: a randomized, intrapatient left-to-right trial", Br J Dermatol, 168, pp.1287~1293 (2013)
- Handrick C, "Comparison of long-pulsed diode and long-pulsed alexandrite lasers for hair removal: a longterm clinical and histologic study", Dermatol Surg, 27, pp.622~626 (2001)
