본문 바로가기
KERD
논문KCI 등재

교뇌외수초용해증에서 발현한 동결보행

Freezing of Gait in Extrapontine Myelinolysis

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류신경과학

초록

A 65-year-old female visited us due to gait disturbance. A neurological examination showed cognitive impairment, dystonia, myoclonus, bradykinesia, postural instability, and freezing of gait (FOG). She was diagnosed with extrapontine myelinolysis based on her history of hyponatremia and high signal intensities (HSIs) in both striata on T2-weighted images. Her neurological problems including FOG improved over 25 days. In a follow-up MRI 50 days after the onset, HSIs disappeared in the striata but new ones appeared in the pons. FOG may have been related to striatal dysfunction in this patient.

Abstract

A 65-year-old female visited us due to gait disturbance. A neurological examination showed cognitive impairment, dystonia, myoclonus, bradykinesia, postural instability, and freezing of gait (FOG). She was diagnosed with extrapontine myelinolysis based on her history of hyponatremia and high signal intensities (HSIs) in both striata on T2-weighted images. Her neurological problems including FOG improved over 25 days. In a follow-up MRI 50 days after the onset, HSIs disappeared in the striata but new ones appeared in the pons. FOG may have been related to striatal dysfunction in this patient.

참고문헌 (10)

  1. Kallakatta RN, "Clinical and functional outcome and factors predicting prognosis in osmotic demyelination syndrome (central pontine and", or extrapontine myelinolysis) in 25 patients, 2011, pp.82, 326~331
  2. Wu YC, "(99m)tc-TRODAT-1 and (123)I-IBZM SPECT studies in a patient with extrapontine myelinolysis with parkinsonian features", Ann Nucl Med, 23, pp.409~412 (2009)
  3. Nobili F, "Brain perfusion correlates of cognitive and nigrostriatal functions in de novo Parkinson's disease", Eur J Nucl Med Mol Imaging, 38, pp.2209~2218 (2011)
  4. dopa positron-emission tomography study, "Mov Disord", 1997, 1035~1038
  5. Förster A, "Value of diffusion-weighted imaging in central pontine and extrapontine myelinolysis", Neuroradiology, 55, pp.49~56 (2013)
  6. Krystkowiak P, "Gait abnormalities induced by acquired bilateral pallidal lesions: a motion analysis study", J Neurol, 253, pp.594~600 (2006)
  7. Schrader C, "GPi-DBS may induce a hypokinetic gait disorder with freezing of gait in patients with dystonia", Neurology, 77, pp.483~488 (2011)
  8. Chang CC, "Clinical significance of the pallidoreticular pathway in patients with carbon monoxide intoxication", Brain, 134, pp.3632~3646 (2011)
  9. Golestanirad L, "Efficacy and safety of pedunculopontine nuclei (PPN) deep brain stimulation in the treatment of gait disorders: A meta-analysis of clinical studies", Can J Neurol Sci, 43, pp.120~126 (2016)
  10. Bartels AL, "Striatal dopa and glucose metabolism in PD patients with freezing of gait", Mov Disord, 21, pp.1326~1332 (2006)

관련 논문AI추천

이 간행물의 다른 논문 (30건)